目的基于倾向性评分匹配(PSM),比较机器人与腹腔镜辅助下行结直肠癌根治术对患者围手术期各项结局指标的影响,探索机器人手术开展前、中期的最佳手术获益人群特点。方法回顾性分析2022年1月至2023年12月重庆医科大学附属第二医院行结直...目的基于倾向性评分匹配(PSM),比较机器人与腹腔镜辅助下行结直肠癌根治术对患者围手术期各项结局指标的影响,探索机器人手术开展前、中期的最佳手术获益人群特点。方法回顾性分析2022年1月至2023年12月重庆医科大学附属第二医院行结直肠癌根治术的患者资料,基于患者性别、年龄、身体质量指数(BMI)及手术部位进行PSM,主要结局是匹配后队列的术后短期结局(二次手术率、首次排气时间、首次进食流食时间、术后住院时间、总住院时间),次要结局是匹配后队列的术中情况(手术时间、估计失血量、术中输血率、中转开腹率、淋巴结清扫数目)和术后感染性并发症发生率。结果本研究共纳入1031例患者资料,将机器人组(n=147)与腹腔镜组(n=884)患者进行1∶1 PSM后,共保留142对研究对象。匹配后的队列中,腹腔镜组的手术时间短于机器人组[179.48(69.88)min vs 237.98(82.27)min,U=6.849,P<0.01],机器人组与腹腔镜组在估计失血量[50(20)mL vs 50(30)mL,U=2.746,P=0.006]、首次进食流食时间[(3.86±1.87)d vs(4.27±1.70)d,t=2.194,P=0.028]、首次排气时间[2.0(1.0)d vs 3.0(1.0)d,U=2.022,P=0.043]、术后住院时间[9.5(2.0)d vs 10.0(4.0)d,U=2.790,P=0.005]、总住院时间[14.0(4.0)d vs 15.0(6.0)d,U=2.574,P=0.010]和感染性并发症发生率(11.3%vs 23.2%,P=0.008)方面差异有统计学意义。两组的术中输血发生率、中转开腹率、淋巴结清扫数目、二次手术发生率差异无统计学意义(P>0.05)。亚组分析显示,年龄<65岁、女性、BMI为18.5~23.9 kg/m2、接受直肠癌根治术的患者是机器人手术的最佳获益人群。结论机器人手术在术后恢复方面和感染性并发症发生率方面优于腹腔镜手术,建议术者在开展机器人手术的前、中期,对年龄<65岁、女性、BMI为18.5~23.9 kg/m2患者可优先考虑行机器人手术。展开更多
The fungal communities in mushroom compost phase Ⅱ was assessed using a combination of PCR amplification and sequencing of 18S rDNA from fungal isolates and “nested” PCR TGGE analysis on the basis of DNA directly e...The fungal communities in mushroom compost phase Ⅱ was assessed using a combination of PCR amplification and sequencing of 18S rDNA from fungal isolates and “nested” PCR TGGE analysis on the basis of DNA directly extracted from compost samples. The diversity of cultivated fungi isolated from compost samples was low. A total of 11 isolates were related to only 2 different species. One species, Chaetomium elatum, was identified within 10 isolates, and the other, with high similarity belonged to Penicillium expansum. The fungal flora associated with mushroom compost was then monitored with “nested” PCR TGGE. The patterns obtained revealed the more complex existence of fungal communities from the original compost samples than from thoses enriched with food waste and cow slurry.展开更多
Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity be...Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity benefitting from structural diversity and design flexibility.However,the potential of MOFs for optoelectronics has been largely overlooked and their applications in optical logic have not been exploited.Here,through temporally manipulating the nonlinear optical absorption process in porphyrin-based MOFs,we have successfully developed AND and XOR logic gates with an ultrafast speed approaching 1 THz and an on–off ratio above 90%.On this basis,all-optical information encryption is further demonstrated using transmittance as primary codes,which shows vast prospects in avoiding the disclosure of security information.To the best of our knowledge,this is the first exploration of MOFs for applications in ultrafast optical logic devices and information encryption.展开更多
文摘目的基于倾向性评分匹配(PSM),比较机器人与腹腔镜辅助下行结直肠癌根治术对患者围手术期各项结局指标的影响,探索机器人手术开展前、中期的最佳手术获益人群特点。方法回顾性分析2022年1月至2023年12月重庆医科大学附属第二医院行结直肠癌根治术的患者资料,基于患者性别、年龄、身体质量指数(BMI)及手术部位进行PSM,主要结局是匹配后队列的术后短期结局(二次手术率、首次排气时间、首次进食流食时间、术后住院时间、总住院时间),次要结局是匹配后队列的术中情况(手术时间、估计失血量、术中输血率、中转开腹率、淋巴结清扫数目)和术后感染性并发症发生率。结果本研究共纳入1031例患者资料,将机器人组(n=147)与腹腔镜组(n=884)患者进行1∶1 PSM后,共保留142对研究对象。匹配后的队列中,腹腔镜组的手术时间短于机器人组[179.48(69.88)min vs 237.98(82.27)min,U=6.849,P<0.01],机器人组与腹腔镜组在估计失血量[50(20)mL vs 50(30)mL,U=2.746,P=0.006]、首次进食流食时间[(3.86±1.87)d vs(4.27±1.70)d,t=2.194,P=0.028]、首次排气时间[2.0(1.0)d vs 3.0(1.0)d,U=2.022,P=0.043]、术后住院时间[9.5(2.0)d vs 10.0(4.0)d,U=2.790,P=0.005]、总住院时间[14.0(4.0)d vs 15.0(6.0)d,U=2.574,P=0.010]和感染性并发症发生率(11.3%vs 23.2%,P=0.008)方面差异有统计学意义。两组的术中输血发生率、中转开腹率、淋巴结清扫数目、二次手术发生率差异无统计学意义(P>0.05)。亚组分析显示,年龄<65岁、女性、BMI为18.5~23.9 kg/m2、接受直肠癌根治术的患者是机器人手术的最佳获益人群。结论机器人手术在术后恢复方面和感染性并发症发生率方面优于腹腔镜手术,建议术者在开展机器人手术的前、中期,对年龄<65岁、女性、BMI为18.5~23.9 kg/m2患者可优先考虑行机器人手术。
文摘The fungal communities in mushroom compost phase Ⅱ was assessed using a combination of PCR amplification and sequencing of 18S rDNA from fungal isolates and “nested” PCR TGGE analysis on the basis of DNA directly extracted from compost samples. The diversity of cultivated fungi isolated from compost samples was low. A total of 11 isolates were related to only 2 different species. One species, Chaetomium elatum, was identified within 10 isolates, and the other, with high similarity belonged to Penicillium expansum. The fungal flora associated with mushroom compost was then monitored with “nested” PCR TGGE. The patterns obtained revealed the more complex existence of fungal communities from the original compost samples than from thoses enriched with food waste and cow slurry.
基金This work was subsidized by the Special Funds for Major State Basic Research Projects(G 1999064800)the National Natural Science Foundation (2973414150103012) and SKLEP (0062).
文摘Two novel iron-based catalysts have been synthesized with high catalytic activity (about 108g oligomers/molFe穐) for ethylene oligomerization.
基金supported by Science Challenge Project(no.TZ2018001)National Natural Science Foundation of China(nos.11872058 and 21802036)Project of State Key Laboratory of Environment-friendly Energy Materials,and Southwest University of Science and Technology(21fksy07).
文摘Optical logic gates call for materials with giant optical nonlinearity to break the current performance bottleneck.Metal–organic frameworks(MOFs)provide an intriguing route to achieve superior optical nonlinearity benefitting from structural diversity and design flexibility.However,the potential of MOFs for optoelectronics has been largely overlooked and their applications in optical logic have not been exploited.Here,through temporally manipulating the nonlinear optical absorption process in porphyrin-based MOFs,we have successfully developed AND and XOR logic gates with an ultrafast speed approaching 1 THz and an on–off ratio above 90%.On this basis,all-optical information encryption is further demonstrated using transmittance as primary codes,which shows vast prospects in avoiding the disclosure of security information.To the best of our knowledge,this is the first exploration of MOFs for applications in ultrafast optical logic devices and information encryption.
