Objective To explore the medication patterns of Professor Zulong Wang in treating sleep-related painful erection(SRPE)through data mining,aiming to discover new therapeutic strategies for traditional Chinese medicine ...Objective To explore the medication patterns of Professor Zulong Wang in treating sleep-related painful erection(SRPE)through data mining,aiming to discover new therapeutic strategies for traditional Chinese medicine in managing this condition.Methods Medical records of SRPE patients treated by Professor Zulong Wang at the First Affiliated Hospital of Henan University of Chinese Medicine from February 2021 to December 2024 were collected to establish a database.Frequency analysis,association rule analysis,and cluster analysis were employed to examine the frequency of herb use,four properties and five flavors,channel tropisms,and herb combinations.Results A total of 59 prescriptions meeting the criteria were included,involving 81 Chinese herbs,among which 27 herbs were used 10 or more times.The primary herb properties were cold,warm,and neutral,with bitter,sweet,and pungent flavors being most common.The herbs predominantly entered the liver,heart,spleen,and kidney channels.Forty-three commonly used herb combinations were identified,and cluster analysis revealed six core herb groups.Conclusion Professor Zulong Wang primarily treats SRPE with modified Huoluo Xiaoling Dan,focusing on unblocking collaterals and relieving pain,supplemented by soothing the liver and regulating qi,resolving stasis and phlegm,nourishing yin and reducing fire,and tonifying the kidney and activating blood circulation.展开更多
The use of H2SO4‐,HCl‐,H3PO4‐,and CH3COOH‐activated montmorillonite(Mt)and WOx/H3PO4‐activated Mt as catalysts for the gas‐phase dehydration of glycerol was investigated.The WOx/H3PO4‐activated Mt catalysts wer...The use of H2SO4‐,HCl‐,H3PO4‐,and CH3COOH‐activated montmorillonite(Mt)and WOx/H3PO4‐activated Mt as catalysts for the gas‐phase dehydration of glycerol was investigated.The WOx/H3PO4‐activated Mt catalysts were prepared by an impregnation method using H3PO4‐activated Mt(Mt‐P)as the support.The catalysts were characterized using powder X‐ray diffraction,Fourier‐transform infrared spectroscopy,N2adsorption‐desorption,diffuse reflectance ultraviolet‐visible spectroscopy,temperature‐programmed desorption of NH3,and thermogravimetric analysis.The acid activation of Mt and WOx loaded on Mt‐P affected the strength and number of acid sites arising from H+exchange,the leaching of octahedral Al3+cations from Mt octahedral sheets,and the types of WOx(2.7≤x≤3)species(i.e.,isolated WO4/WO6‐containing clusters,two‐dimensional[WO6]polytungstates,or three‐dimensional WO3crystals).The strong acid sites were weakened,and the weak and medium acid sites were strengthened when the W loading on Mt‐P was12wt%(12%W/Mt‐P).The12%W/Mt‐P catalyst showed the highest catalytic activity.It gave a glycerol conversion of89.6%and an acrolein selectivity of81.8%at320°C.Coke deposition on the surface of the catalyst led to deactivation.展开更多
基金supported by the National Natural Science Foundation of China General Program(82174377)National Traditional Chinese Medicine Advantageous Specialty Construction Project(GZY-ZY[2024]90).
文摘Objective To explore the medication patterns of Professor Zulong Wang in treating sleep-related painful erection(SRPE)through data mining,aiming to discover new therapeutic strategies for traditional Chinese medicine in managing this condition.Methods Medical records of SRPE patients treated by Professor Zulong Wang at the First Affiliated Hospital of Henan University of Chinese Medicine from February 2021 to December 2024 were collected to establish a database.Frequency analysis,association rule analysis,and cluster analysis were employed to examine the frequency of herb use,four properties and five flavors,channel tropisms,and herb combinations.Results A total of 59 prescriptions meeting the criteria were included,involving 81 Chinese herbs,among which 27 herbs were used 10 or more times.The primary herb properties were cold,warm,and neutral,with bitter,sweet,and pungent flavors being most common.The herbs predominantly entered the liver,heart,spleen,and kidney channels.Forty-three commonly used herb combinations were identified,and cluster analysis revealed six core herb groups.Conclusion Professor Zulong Wang primarily treats SRPE with modified Huoluo Xiaoling Dan,focusing on unblocking collaterals and relieving pain,supplemented by soothing the liver and regulating qi,resolving stasis and phlegm,nourishing yin and reducing fire,and tonifying the kidney and activating blood circulation.
基金supported by the National Natural Science Foundation of China(21373185,41672033,21506188,21404090)the Open Project Programs of Engineering Research Center of Non-metallic Minerals of Zhejiang Province(ZD2015k07)+2 种基金of State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology(GCTKF2014006)of Key Laboratory of High Efficient Processing of Bamboo of Zhejiang Province(2016)of State Key Laboratory of Chemical Resource Engineering,Beijing University of Chemical Technology(CRE-2016-C-303)~~
文摘The use of H2SO4‐,HCl‐,H3PO4‐,and CH3COOH‐activated montmorillonite(Mt)and WOx/H3PO4‐activated Mt as catalysts for the gas‐phase dehydration of glycerol was investigated.The WOx/H3PO4‐activated Mt catalysts were prepared by an impregnation method using H3PO4‐activated Mt(Mt‐P)as the support.The catalysts were characterized using powder X‐ray diffraction,Fourier‐transform infrared spectroscopy,N2adsorption‐desorption,diffuse reflectance ultraviolet‐visible spectroscopy,temperature‐programmed desorption of NH3,and thermogravimetric analysis.The acid activation of Mt and WOx loaded on Mt‐P affected the strength and number of acid sites arising from H+exchange,the leaching of octahedral Al3+cations from Mt octahedral sheets,and the types of WOx(2.7≤x≤3)species(i.e.,isolated WO4/WO6‐containing clusters,two‐dimensional[WO6]polytungstates,or three‐dimensional WO3crystals).The strong acid sites were weakened,and the weak and medium acid sites were strengthened when the W loading on Mt‐P was12wt%(12%W/Mt‐P).The12%W/Mt‐P catalyst showed the highest catalytic activity.It gave a glycerol conversion of89.6%and an acrolein selectivity of81.8%at320°C.Coke deposition on the surface of the catalyst led to deactivation.
