Summary What is already known about this topic?Menstrual irregularity is a hallmark clinical feature of polycystic ovary syndrome(PCOS),which is an established risk factor for spontaneous abortion.However,robust popul...Summary What is already known about this topic?Menstrual irregularity is a hallmark clinical feature of polycystic ovary syndrome(PCOS),which is an established risk factor for spontaneous abortion.However,robust population-level evidence directly linking specific patterns of menstrual irregularity to spontaneous abortion risk remains lacking,as prior studies have been limited by small sample sizes.展开更多
Summary What is already known about this topic?Hematological parameters may indicate the presence of chronic low-grade inflammation and increasing viscosity,which are involved in the pathological processes of gestatio...Summary What is already known about this topic?Hematological parameters may indicate the presence of chronic low-grade inflammation and increasing viscosity,which are involved in the pathological processes of gestational diabetes mellitus(GDM).However,the association between several hematological parameters in early pregnancy and GDM has yet to be elucidated.What is added by this report?Hematological parameters in the first trimester,particularly red blood cell(RBC)count and systematic immune index,have a significant impact on GDM incidence.The neutrophils(NEU)count in the first trimester was particularly pronounced for GDM.The upward trend of RBC,white blood cell(WBC),and NEU counts was consistent across all GDM subtypes.What are the implications for public health practice?Early pregnancy hematological parameters are associated with the risk of GDM.展开更多
Summary What is already known about this topic?The significance of maternal liver health concerning preterm birth(PTB)is well recognized;however,there is a gap in understanding the precise influence of preconception s...Summary What is already known about this topic?The significance of maternal liver health concerning preterm birth(PTB)is well recognized;however,there is a gap in understanding the precise influence of preconception serum alanine aminotransferase(ALT)levels on the risk of PTB.What is added by this report?展开更多
基金Supported by the National Key Research and Development Program of China(NKPs)under grants 2021YFC2700705(Ms.Yang)and 2016YFC100307(Mr.Ma).
文摘Summary What is already known about this topic?Menstrual irregularity is a hallmark clinical feature of polycystic ovary syndrome(PCOS),which is an established risk factor for spontaneous abortion.However,robust population-level evidence directly linking specific patterns of menstrual irregularity to spontaneous abortion risk remains lacking,as prior studies have been limited by small sample sizes.
基金Supported by the National Key Research and Development Program of China(NKPs)[Grant no.2021YFC2700705].
文摘Summary What is already known about this topic?Hematological parameters may indicate the presence of chronic low-grade inflammation and increasing viscosity,which are involved in the pathological processes of gestational diabetes mellitus(GDM).However,the association between several hematological parameters in early pregnancy and GDM has yet to be elucidated.What is added by this report?Hematological parameters in the first trimester,particularly red blood cell(RBC)count and systematic immune index,have a significant impact on GDM incidence.The neutrophils(NEU)count in the first trimester was particularly pronounced for GDM.The upward trend of RBC,white blood cell(WBC),and NEU counts was consistent across all GDM subtypes.What are the implications for public health practice?Early pregnancy hematological parameters are associated with the risk of GDM.
基金Supported by the National Key Research and Development Program of China(NKPs)under grants 2021YFC2700705(Ms.Yang)and 2016YFC100307(Mr.Ma).
文摘Summary What is already known about this topic?The significance of maternal liver health concerning preterm birth(PTB)is well recognized;however,there is a gap in understanding the precise influence of preconception serum alanine aminotransferase(ALT)levels on the risk of PTB.What is added by this report?
