Genomic islands （Gis） are one of the most important components for cyanobacterial genome. The Gis code has many functions, such as symbiosis, pathogenesis, and adaptation. In this article, we predict and analyze the...Genomic islands （Gis） are one of the most important components for cyanobacterial genome. The Gis code has many functions, such as symbiosis, pathogenesis, and adaptation. In this article, we predict and analyze the Gis in Synechocystis sp. PCC 6803 by bioinfomatics, and the results show that ISL1, ISL8, and ISL16 are homologous with many other bacteria, and they involve in basic reactions and have a conservative evolution. On the contrary, ISL15 has a unique sequence and function only for Synechocystis sp. PCC 6803. Most of Gis play a role in genome rearrangement because they have lots of transposase. Moreover, we find that recombination and horizontal transfer of Gis are important factors to affect the distribution of non-coding RNA. Our work contributes to a comprehensive understanding of genomic islands and their impact on genome of cyanobacteria.展开更多
基金supported by the National Natural Science Foundation of China under Grant No.81171411the Key Technology Research and the Development Program of Sichuan Province under Grant No.2011FZ0034
文摘Genomic islands （Gis） are one of the most important components for cyanobacterial genome. The Gis code has many functions, such as symbiosis, pathogenesis, and adaptation. In this article, we predict and analyze the Gis in Synechocystis sp. PCC 6803 by bioinfomatics, and the results show that ISL1, ISL8, and ISL16 are homologous with many other bacteria, and they involve in basic reactions and have a conservative evolution. On the contrary, ISL15 has a unique sequence and function only for Synechocystis sp. PCC 6803. Most of Gis play a role in genome rearrangement because they have lots of transposase. Moreover, we find that recombination and horizontal transfer of Gis are important factors to affect the distribution of non-coding RNA. Our work contributes to a comprehensive understanding of genomic islands and their impact on genome of cyanobacteria.
