Miniaturization of photoacoustic microscopy(PAM)to portable and wearable levels requires special design of scanning,detection,acquisition,and excitation units.Now the first three can be minimized to gram and millimete...Miniaturization of photoacoustic microscopy(PAM)to portable and wearable levels requires special design of scanning,detection,acquisition,and excitation units.Now the first three can be minimized to gram and millimeter levels,but the excitation sources usually remain bulky and also face different challenges,including low pulse energy,wide pulse width,limited wavelength,or high cost.展开更多
In photoacoustic imaging(PAI),a nanosecond laser with the controllable pulse width(PW)and pulse number(PN)benefits variable photoacoustic(PA)frequencies and nonlinear excitations.Here,we report a compact(1-mm-long cav...In photoacoustic imaging(PAI),a nanosecond laser with the controllable pulse width(PW)and pulse number(PN)benefits variable photoacoustic(PA)frequencies and nonlinear excitations.Here,we report a compact(1-mm-long cavity)gainswitched laser that directly generates tunable PW(18-110 ns)and PN(1-4)with pulse intervals(236-553 ns),as well as adjustable repetition rates(5-35 kHz),utilizing the relaxation oscillation effect.We showcase the tunable PW excitation and the PA enhancement of 33.9%under multi-pulse excitation.The promising performance suggests that the laser can be flexibly applied in functional and nonlinear PAI systems.展开更多
基金National Natural Science Foundation of China(62305274,62475222,62205163)NaturalScience Foundation of Xiamen Municipality(3502Z202371001,3502Z20227162)+1 种基金Natural Science Foundation of Fujian Province(2024J01056)Xiamen University(20720240025).
文摘Miniaturization of photoacoustic microscopy(PAM)to portable and wearable levels requires special design of scanning,detection,acquisition,and excitation units.Now the first three can be minimized to gram and millimeter levels,but the excitation sources usually remain bulky and also face different challenges,including low pulse energy,wide pulse width,limited wavelength,or high cost.
基金supported by the National Natural Science Foundation of China(Nos.62305274 and 62475222)the Natural Science Foundation of Xiamen City,China(No.3502Z202371001)+1 种基金the Fujian Provincial Natural Science Foundation of China(No.2024J01056)the Fundamental Research Funds for the Central Universities(No.20720240025)。
文摘In photoacoustic imaging(PAI),a nanosecond laser with the controllable pulse width(PW)and pulse number(PN)benefits variable photoacoustic(PA)frequencies and nonlinear excitations.Here,we report a compact(1-mm-long cavity)gainswitched laser that directly generates tunable PW(18-110 ns)and PN(1-4)with pulse intervals(236-553 ns),as well as adjustable repetition rates(5-35 kHz),utilizing the relaxation oscillation effect.We showcase the tunable PW excitation and the PA enhancement of 33.9%under multi-pulse excitation.The promising performance suggests that the laser can be flexibly applied in functional and nonlinear PAI systems.