酗酒是一个全球性的重大社会问题,是导致残疾和早死的主要危险因素之一。近来长期饮酒者大脑中发生的神经免疫信号改变已成为众多酒精使用障碍(alcohol use disorders, AUD)神经病理学研究的重点。研究发现酒精可通过先天性免疫受体Tol...酗酒是一个全球性的重大社会问题,是导致残疾和早死的主要危险因素之一。近来长期饮酒者大脑中发生的神经免疫信号改变已成为众多酒精使用障碍(alcohol use disorders, AUD)神经病理学研究的重点。研究发现酒精可通过先天性免疫受体Toll样受体(Toll-like receptors, TLRs)激活中枢神经系统的神经免疫信号,诱导细胞因子和趋化因子的释放,最终导致与酒精滥用相关的神经炎症、神经元死亡、脑功能性损害及成瘾。本文将对Toll样受体通过神经免疫参与酒精使用障碍的相关机制进行综述,为通过神经免疫途径治疗酒精使用障碍提供理论基础。展开更多
By means of the classical symmetry method,we investigate two types of the(2+1)-dimensional nonlinearKlein-Gorden equation.For the wave equation,we give out its symmetry group analysis in detail.For the secondtype of t...By means of the classical symmetry method,we investigate two types of the(2+1)-dimensional nonlinearKlein-Gorden equation.For the wave equation,we give out its symmetry group analysis in detail.For the secondtype of the(2+1)-dimensional nonlinear Klein-Gorden equation,an optimal system of its one-dimensional subalgebrasis constructed and some corresponding two-dimensional symmetry reductions are obtained.展开更多
On bases of the direct method developed by Clarkson and Kruskal [J.Math.Phys.27 (1989) 2201],the(2+1)-dimensional nonisospectral Kadomtsev-Petviashvili (KP) equation has been reduced to three types of (1+1)-dimensiona...On bases of the direct method developed by Clarkson and Kruskal [J.Math.Phys.27 (1989) 2201],the(2+1)-dimensional nonisospectral Kadomtsev-Petviashvili (KP) equation has been reduced to three types of (1+1)-dimensional partial differential equations.We focus on solving the third type of reduction and dividing them into threesubcases,from which we obtain rich solutions including some arbitrary functions.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos.10735030 and 90718041Shanghai Leading Academic Discipline Project under Grant No.B412+1 种基金Program for Changjiang Scholars and Innovative Research Team in University (IRT0734)K.C.Wong Magna Fund in Ningbo University
文摘By means of the classical symmetry method,we investigate two types of the(2+1)-dimensional nonlinearKlein-Gorden equation.For the wave equation,we give out its symmetry group analysis in detail.For the secondtype of the(2+1)-dimensional nonlinear Klein-Gorden equation,an optimal system of its one-dimensional subalgebrasis constructed and some corresponding two-dimensional symmetry reductions are obtained.
基金supported by National Natural Science Foundation of China under Grant Nos.10735030 and 90718141Shanghai Leading Academic Discipline Project under Grant No.B412+3 种基金Natural Science Foundations of Zhejiang Province of China under Grant No.Y604056Doctoral Foundation of Ningbo City under Grant No.2005A61030Program for Changjiang Scholars and Innovative Research Team in University under Grant No.IRT0734K.C.Wang Magna Fund in Ningbo University
文摘On bases of the direct method developed by Clarkson and Kruskal [J.Math.Phys.27 (1989) 2201],the(2+1)-dimensional nonisospectral Kadomtsev-Petviashvili (KP) equation has been reduced to three types of (1+1)-dimensional partial differential equations.We focus on solving the third type of reduction and dividing them into threesubcases,from which we obtain rich solutions including some arbitrary functions.