In this paper,a novel Filter bank multicarrier/quadrature amplitude modulation(FBMC/QAM)scheme which separates the real and imaginary part of the subcarriers in a multipath time-varying fading channel is put forward a...In this paper,a novel Filter bank multicarrier/quadrature amplitude modulation(FBMC/QAM)scheme which separates the real and imaginary part of the subcarriers in a multipath time-varying fading channel is put forward and analyzed in detail.By applying the methods of mapping the time-domain symbols and reducing the correlation of frequency-domain symbols,the presented scheme can eliminate the intrinsic imaginary interference more thoroughly and greatly mitigate residual interference as well as receive a good peak-to-average power ratio(PAPR)mitigation effect.Theoretical analysis and simulation results indicate that compared with the existing schemes with the methods of pre-coding(FBMC/QAM-CC)and iterative interference cancellation(FBMC/QAM-IIC),our adopted scheme can not only obtain better performances on bit error rate(BER)and out-of-band(OOB)emission with no loss of transmission efficiency,but also achieve a good PAPR mitigation effect with a small increase in complexity.展开更多
目的探讨二甲双胍联合达格列净治疗2型糖尿病(T2DM)的疗效及对机体微炎症状态的影响。方法选取T2DM患者80例,按随机数字表法均分为观察组与对照组。对照组用二甲双胍治疗,观察组用二甲双胍联合达格列净治疗,疗程为12周。对比2组不良反...目的探讨二甲双胍联合达格列净治疗2型糖尿病(T2DM)的疗效及对机体微炎症状态的影响。方法选取T2DM患者80例,按随机数字表法均分为观察组与对照组。对照组用二甲双胍治疗,观察组用二甲双胍联合达格列净治疗,疗程为12周。对比2组不良反应或并发症发生情况,检测并比较2组治疗前后糖脂代谢指标[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)、稳态模型胰岛素抵抗指数(HOMA-IR)]、体质量指数(BMI)、收缩压(SBP)、舒张压(DBP)、肾功能相关指标[胱抑素C(CysC)、尿微量白蛋白/尿肌酐比值(ACR)]及炎症指标[C反应蛋白(CRP)和同型半胱氨酸(Hcy)]。结果治疗后,观察组的FBG达标时间明显短于对照组,HbA1c达标率高于对照组(P<0.05)。观察组的FBG、2 h PG、HbA1c、HOMA-IR、BMI、SBP、三酰甘油(TG)、CRP、Hcy、CysC和ACR均低于对照组(P<0.05);2组SBP、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)比较差异无统计学意义。2组不良反应率比较,差异无统计学意义。结论二甲双胍联合达格列净治疗T2DM能够提高血糖控制效果,减轻胰岛素抵抗及机体微炎症状态,对体质量控制更具优势且未增加低血糖事件发生风险。展开更多
基金supported by the National Natural Science Foundation of China(No.61601296 and No.61701295)the Talent Program of Shanghai University of Engineering Science(No.2018RC43).
文摘In this paper,a novel Filter bank multicarrier/quadrature amplitude modulation(FBMC/QAM)scheme which separates the real and imaginary part of the subcarriers in a multipath time-varying fading channel is put forward and analyzed in detail.By applying the methods of mapping the time-domain symbols and reducing the correlation of frequency-domain symbols,the presented scheme can eliminate the intrinsic imaginary interference more thoroughly and greatly mitigate residual interference as well as receive a good peak-to-average power ratio(PAPR)mitigation effect.Theoretical analysis and simulation results indicate that compared with the existing schemes with the methods of pre-coding(FBMC/QAM-CC)and iterative interference cancellation(FBMC/QAM-IIC),our adopted scheme can not only obtain better performances on bit error rate(BER)and out-of-band(OOB)emission with no loss of transmission efficiency,but also achieve a good PAPR mitigation effect with a small increase in complexity.
文摘目的探讨二甲双胍联合达格列净治疗2型糖尿病(T2DM)的疗效及对机体微炎症状态的影响。方法选取T2DM患者80例,按随机数字表法均分为观察组与对照组。对照组用二甲双胍治疗,观察组用二甲双胍联合达格列净治疗,疗程为12周。对比2组不良反应或并发症发生情况,检测并比较2组治疗前后糖脂代谢指标[空腹血糖(FBG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)、稳态模型胰岛素抵抗指数(HOMA-IR)]、体质量指数(BMI)、收缩压(SBP)、舒张压(DBP)、肾功能相关指标[胱抑素C(CysC)、尿微量白蛋白/尿肌酐比值(ACR)]及炎症指标[C反应蛋白(CRP)和同型半胱氨酸(Hcy)]。结果治疗后,观察组的FBG达标时间明显短于对照组,HbA1c达标率高于对照组(P<0.05)。观察组的FBG、2 h PG、HbA1c、HOMA-IR、BMI、SBP、三酰甘油(TG)、CRP、Hcy、CysC和ACR均低于对照组(P<0.05);2组SBP、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)比较差异无统计学意义。2组不良反应率比较,差异无统计学意义。结论二甲双胍联合达格列净治疗T2DM能够提高血糖控制效果,减轻胰岛素抵抗及机体微炎症状态,对体质量控制更具优势且未增加低血糖事件发生风险。
