Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,an...Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.展开更多
Traditional Chinese Medicine(TCM)is a treasure of China’s traditional medical heritage,embodying the wisdom and cultural depth of the Chinese nation.Higher TCM education shoulders the important responsibility of pres...Traditional Chinese Medicine(TCM)is a treasure of China’s traditional medical heritage,embodying the wisdom and cultural depth of the Chinese nation.Higher TCM education shoulders the important responsibility of preserving and advancing TCM,and in today’s context,it offers significant advantages while also facing numerous challenges.Among its strengths are a profound cultural foundation in TCM,utilizing classic texts and unique theories to cultivate students’TCM thinking and competence;diversified teaching methods that integrate knowledge from multiple disciplines,innovate instructional models,and combine traditional with modern educational approaches;a complete teaching system characterized by professional faculty and advanced facilities;and interdisciplinary integration fostering innovation.However,problems persist,including some students lacking confidence in TCM culture due to the influence of Western medicine concepts and the westernization of the educational model;weak practical teaching where theory dominates,practice time is limited,and there are insufficient bases and instructors;and a shortage of faculty resulting in an imbalanced student-to-teacher ratio and an unreasonable structure.To address these issues,it is recommended to enhance cultural confidence,strengthen faculty development,and optimize practical teaching,thereby promoting the sustainable development of higher TCM education and achieving the shared prosperity of TCM education and the TCM profession.展开更多
Standardized residency training programs primarily focus on developing clinical diagnostic and treatment skills,often allocating limited time to research activities.However,enhancing research skills is of paramount im...Standardized residency training programs primarily focus on developing clinical diagnostic and treatment skills,often allocating limited time to research activities.However,enhancing research skills is of paramount importance for residents,as it fosters critical thinking,problem-solving abilities,and a deeper understanding of applying scientific principles to clinical practice.This paper explores the necessity and significance of integrating research training into residency programs,emphasizing its role in cultivating well-rounded physicians capable of advancing medical knowledge.This study proposes a competency-based research training model that encompasses research literacy,study design,biostatistics,and scientific writing.Additionally,online asynchronous training modules,robust mentorship,and balanced time management strategies are recommended to enhance residents’research engagement without compromising clinical training.By implementing these measures,residency programs can improve residents’research capabilities,contributing to both individual professional growth and the broader advancement of medical science.展开更多
As a core mechanism for training talents in Chinese medicine,a follow-up study has constructed a unique Chinese medicine education model through the in-depth intermingling of teacher-training mode and clinical practic...As a core mechanism for training talents in Chinese medicine,a follow-up study has constructed a unique Chinese medicine education model through the in-depth intermingling of teacher-training mode and clinical practice.In the process of teacher training,the tutor transfers the implicit knowledge such as identification thinking and medication experience in the form of“oral transmission and clinical instruction,”so that the academic postgraduates of Chinese medicine can understand the holistic view of the correspondence between heaven and man,the methodology of identification and treatment,and the internal logic of rationale,methodology,prescription and medicine in the clinical diagnosis and treatment.This kind of transmission not only strengthens the students’basic clinical skills of combining the four diagnoses and analyzing the evidence,but also fosters their academic innovation ability of applying classical theories to solve complex clinical problems through the in-depth analysis of typical medical cases.In this paper,we discuss the significance of teacher-training education in the training of academic postgraduates in Chinese medicine,and propose an optimization path for the reference of higher education in Chinese medicine.展开更多
Interdisciplinary Integrated Teaching is based on constructivist learning theory,systems theory,and collaborative learning theory,emphasising the comprehensive nature of knowledge and its contextual application.Constr...Interdisciplinary Integrated Teaching is based on constructivist learning theory,systems theory,and collaborative learning theory,emphasising the comprehensive nature of knowledge and its contextual application.Constructivism holds that learning is a process of constructing personal cognition through the integration of knowledge from different fields,while systems theory emphasises that the diagnosis and treatment of complex diseases such as RA require a multidisciplinary collaborative perspective.Collaborative learning theory supports the cultivation of students’comprehensive abilities and problem-solving skills through teamwork.RA is a chronic,systemic autoimmune disease involving multiple organ systems and complex management strategies.Interdisciplinary integrated teaching integrates disciplines such as rheumatology and immunology,imaging,and pharmacy to help students understand the pathophysiological mechanisms,diagnostic criteria,treatment protocols,and patient management of RA,thereby enhancing their ability to address complex diseases.展开更多
Exponential nitrogen(N) loading approach has been used to optimize seedling growth in container seedling production. However, the response of seedling growth to N loading and optimal N loading rates are species-depend...Exponential nitrogen(N) loading approach has been used to optimize seedling growth in container seedling production. However, the response of seedling growth to N loading and optimal N loading rates are species-dependent. There is a lack of information on optimal N loading in container production of Australian Blackwood(Acacia melanoxylon) seedlings. In this study, 7 exponential N loading at rates of 0, 50, 100, 200, 300, 400, and 600 mg N seedling-1, respectively, were applied at the week 3, 6, 9, 12 and 14 after transplanting to determine optimal loading approach based on seedling height, root collar diameter(RCD), biomass accumulation and N uptake in tissue-cultured Australian Blackwood(A. melanoxylon) seedlings. Seedlings did not respond to N loading 3 wk after transplanting, then the accumulative addition of N loading for improved RCD and seedling height was 12.99 and 28.02 mg N seedlings-1 in the 100 N and 400 N treatment 6 wk after transplanting, respectively, and on 9 and 12 wk, that for improved seedling growth was 63.64 and 400 mg N seedling-1 in the 200 N and 400 N treatment, respectively. Vector diagnosis of final biomass and N status indicated that the dose of 100 and 400 mg N seedling-1 was characterized to be "deficient" and "optimum" dose of exponential N loading for Blackwood seedlings. These conclusions promise to figure out a precise fertilization regime for Blackwood seedlings and the demonstration of dynamic seedling performance could be used for other tree species.展开更多
Soil erosion in the Three-River Headwaters Region(TRHR)of the Qinghai-Tibet Plateau in China has a significant impact on local economic development and ecological environment.Vegetation and precipitation are considere...Soil erosion in the Three-River Headwaters Region(TRHR)of the Qinghai-Tibet Plateau in China has a significant impact on local economic development and ecological environment.Vegetation and precipitation are considered to be the main factors for the variation in soil erosion.However,it is a big challenge to analyze the impacts of precipitation and vegetation respectively as well as their combined effects on soil erosion from the pixel scale.To assess the influences of vegetation and precipitation on the variation of soil erosion from 2005 to 2015,we employed the Revised Universal Soil Loss Equation(RUSLE)model to evaluate soil erosion in the TRHR,and then developed a method using the Logarithmic Mean Divisia Index model(LMDI)which can exponentially decompose the influencing factors,to calculate the contribution values of the vegetation cover factor(C factor)and the rainfall erosivity factor(R factor)to the variation of soil erosion from the pixel scale.In general,soil erosion in the TRHR was alleviated from 2005 to 2015,of which about 54.95%of the area where soil erosion decreased was caused by the combined effects of the C factor and the R factor,and 41.31%was caused by the change in the R factor.There were relatively few areas with increased soil erosion modulus,of which 64.10%of the area where soil erosion increased was caused by the change in the C factor,and 23.88%was caused by the combined effects of the C factor and the R factor.Therefore,the combined effects of the C factor and the R factor were regarded as the main driving force for the decrease of soil erosion,while the C factor was the dominant factor for the increase of soil erosion.The area with decreased soil erosion caused by the C factor(12.10×10^3 km^2)was larger than the area with increased soil erosion caused by the C factor(8.30×10^3 km^2),which indicated that vegetation had a positive effect on soil erosion.This study generally put forward a new method for quantitative assessment of the impacts of the influencing factors on soil erosion,and also provided a scientific basis for the regional control of soil erosion.展开更多
Objective The aim of this study was to evaluate the impact of the revised Chinese National Standard GB26878-2011 ＇Iodine Content in Edible Salt＇ on the iodine status among the Chinese population. Methods In 2011 and...Objective The aim of this study was to evaluate the impact of the revised Chinese National Standard GB26878-2011 ＇Iodine Content in Edible Salt＇ on the iodine status among the Chinese population. Methods In 2011 and 2014, the probability proportionate to size sampling（PPS） was used in each Chinese province to obtain the representative data. In each sampling unit, school children aged 8-10 years and pregnant women were selected. Key indicators included urinary iodine concentration（UIC）, thyroid volume（TV）, and the iodine content in edible household salt. Results The median urinary iodine concentration（MUIC） decreased between 2011 and 2014 from 238.6 to 197.9 μg/L in school-age children. The number of provinces with iodine excess decreased to zero. The proportion of children whose UIC was 〉 300 μg/L was 18.8% and decreased to 11% compared with 29.8% in 2011. There was no significant difference in UIC 〈 50 μg/L between 2014（4.3%） and 2011（3.7%）（P 〉 0.05）. The MUIC among pregnant women in 2014 was more concentrated between 110 and 230 μg/L. The goiter rate among children aged 8-10 years was unchanged, both the goiter rate of 2011 and 2014 remaining below 5%, in view of the sustainable elimination of iodine deficiency disorders. Conclusion The National Standard GB26878-2011 ＇Iodine Content in Edible Salt＇ that was introduced in March 2012 resulted in an overall improvement in iodine status, reducing the risk of excessive iodine intake in the Chinese population.展开更多
青少年(adolescents and young adults,AYA)是结核病的主要患病群体之一。为了研究针对这个群体的独特性诊断标志物,本研究招募了81名AYA受试者,通过定量蛋白质组学的方法,绘制了AYA结核病患者高质量的血清蛋白质图谱。血清蛋白组数据表...青少年(adolescents and young adults,AYA)是结核病的主要患病群体之一。为了研究针对这个群体的独特性诊断标志物,本研究招募了81名AYA受试者,通过定量蛋白质组学的方法,绘制了AYA结核病患者高质量的血清蛋白质图谱。血清蛋白组数据表明,活动性肺结核(active tuberculosis,ATB)患者中血红蛋白和载脂蛋白相对丰度显著降低。通路富集分析表明,ATB组下调蛋白显著富集于抗氧化、细胞脱毒相关通路,表明存在广泛的氧化应激损伤。通过随机森林(random forest,RF)和极致梯度提升(extreme gradient boosting,XGBoost)联合评估蛋白重要性,获得了一组区分ATB和非ATB的候选蛋白标志物。基于特征递归消除的支持向量机算法,发现载脂蛋白A1(apolipoprotein A-I,APOA1)、血红蛋白亚基α(hemoglobin subunit alpha-1,HBA1)、血红蛋白亚基β(hemoglobin subunit beta,HBB)这3个蛋白的组合在诊断ATB过程中具有最高的准确性和敏感性。临床生化常规检测的血红蛋白(hemoglobin,HGB)和白蛋白(albumin,ALB)含量可以作为评估APOA1、HBB蛋白表达变化的血液生化指标。本研究建立了AYA结核病患者的血清蛋白组全貌,获得了该类群结核病的新诊断标志物。展开更多
Ca-bentonite can be converted into zeolites A through hydrothermal alkaline treatment by varying the synthetic parameters. This study focuses on the effect of initial Si/Al molar ratio, NaOH concentration on the type ...Ca-bentonite can be converted into zeolites A through hydrothermal alkaline treatment by varying the synthetic parameters. This study focuses on the effect of initial Si/Al molar ratio, NaOH concentration on the type of formed zeolite A. The Ca-bentonite (China, Fuxin)were mixed with an aqueous NaOH solution, Al(OH)3 powder and hydrothermally treated at about 90 ℃,12 h. Different types of zeolites (zeolite X, P, and A),sodalite were synthesized after the treatment. Zeolites were characterized and quantified by means of XRD and SEM analysis. Zeolite A predominantly formed with 0.5≤Si/Al≤2.0 was produced and zeolite X, P formed with Si/Al>2.0 under the 2.2mol/LNaOH concentration; Sodalite was also formed under high NaOH molarities. Shape of zeolite A is show the cube by the SEM micrograph.展开更多
Fourteen new geranyl phenyl ethers(1–14)along with three known compounds(15–17)were isolated from Illicium micranthum,and their structures were elucidated by comprehensive spectroscopic methods.Illimicranins A–H(1...Fourteen new geranyl phenyl ethers(1–14)along with three known compounds(15–17)were isolated from Illicium micranthum,and their structures were elucidated by comprehensive spectroscopic methods.Illimicranins A–H(1–8)were characterized as geranyl vanillin ethers,while 9 and 10 were dimethyl acetal derivatives.Illimicranins I and J(11 and 12)were rare geranyl isoeugenol ethers.Illimicranins K and L(13 and 14)represented the first example of geranyl guaiacylacetone ether and geranyl zingerone ether,respectively.Compounds 1,2 and 15 exhibited anti-HBV(hepatitis B virus)activity against HBsAg(hepatitis B surface antigen)and HBeAg(hepatitis B e antigen)secretion,and HBV DNA replication.展开更多
文摘Primary healthcare service is the first line of defense to guard the health of the nation,and traditional Chinese medicine(TCM),with its characteristics of“simplicity,testing and inexpensiveness,”holistic outlook,and the concept of treating the disease before it occurs,has a unique advantage in primary healthcare and a great demand for it.This paper analyzes the core challenges facing the cultivation of general medicine talents in TCM colleges and universities,such as the disconnection between cultivation goals and grassroots,the misalignment between practical ability and grassroots demand,and the lack of career attraction.On this basis,it puts forward a systematic reform path with the core concept of“rooting at the grassroots,highlighting characteristics,and strengthening competence”to cultivate talents that meet grassroots needs,aiming to provide theoretical references for TCM colleges and universities to cultivate excellent TCM talents who are“able to go down to the grassroots,be useful,stay in the field,and have development”,and to provide theoretical reference for the training of excellent TCM talents.The aim is to provide a theoretical reference for Chinese medicine colleges to cultivate excellent Chinese medicine talents who can“get down,use,stay and develop,”and to help the construction of a healthy China.
基金supported by the National Natural Science Foundation of China(Grant No.82260925)Yunnan Provincial High-level Scientific and Technological Talents and Innovative Teams Selection Special Project(Grant No.202305AS350007)+2 种基金Yunnan Provincial Major Scientific and Technological Special Project Program for Biomedicine(Grant No.202402AA310028)Yunnan Province’s High-level Talent Cultivation Project for Successors in Traditional Chinese Medicine Disciplines(Yun Cai She[2024]No.103)Yunnan Provincial Key Laboratory of Dai and Yi Medicine Open Research Topics(2024SS24010).
文摘Traditional Chinese Medicine(TCM)is a treasure of China’s traditional medical heritage,embodying the wisdom and cultural depth of the Chinese nation.Higher TCM education shoulders the important responsibility of preserving and advancing TCM,and in today’s context,it offers significant advantages while also facing numerous challenges.Among its strengths are a profound cultural foundation in TCM,utilizing classic texts and unique theories to cultivate students’TCM thinking and competence;diversified teaching methods that integrate knowledge from multiple disciplines,innovate instructional models,and combine traditional with modern educational approaches;a complete teaching system characterized by professional faculty and advanced facilities;and interdisciplinary integration fostering innovation.However,problems persist,including some students lacking confidence in TCM culture due to the influence of Western medicine concepts and the westernization of the educational model;weak practical teaching where theory dominates,practice time is limited,and there are insufficient bases and instructors;and a shortage of faculty resulting in an imbalanced student-to-teacher ratio and an unreasonable structure.To address these issues,it is recommended to enhance cultural confidence,strengthen faculty development,and optimize practical teaching,thereby promoting the sustainable development of higher TCM education and achieving the shared prosperity of TCM education and the TCM profession.
基金Research on the Construction of a Course Ideological and Political Education System and Evaluation Framework for the“Traditional Chinese Medicine Internal Medicine”Course(Project No.:2025J0459)Open Research Fund Program of Yunnan Key Laboratory of Integrated Traditional Chinese(Project No.:CWCD2023-002,CWCD2023-003&CWCD2023-009)+2 种基金Western Medicine for Chronic Disease in Prevention and TreatmentYunnan 047 Key Laboratory of Yi Dai Medicine and Yi Medicine(Project No.:2024SS24047)Yunnan 025 Key Laboratory of Yi Dai Medicine and Yi Medicine(Project No.:2024SS24025)。
文摘Standardized residency training programs primarily focus on developing clinical diagnostic and treatment skills,often allocating limited time to research activities.However,enhancing research skills is of paramount importance for residents,as it fosters critical thinking,problem-solving abilities,and a deeper understanding of applying scientific principles to clinical practice.This paper explores the necessity and significance of integrating research training into residency programs,emphasizing its role in cultivating well-rounded physicians capable of advancing medical knowledge.This study proposes a competency-based research training model that encompasses research literacy,study design,biostatistics,and scientific writing.Additionally,online asynchronous training modules,robust mentorship,and balanced time management strategies are recommended to enhance residents’research engagement without compromising clinical training.By implementing these measures,residency programs can improve residents’research capabilities,contributing to both individual professional growth and the broader advancement of medical science.
文摘As a core mechanism for training talents in Chinese medicine,a follow-up study has constructed a unique Chinese medicine education model through the in-depth intermingling of teacher-training mode and clinical practice.In the process of teacher training,the tutor transfers the implicit knowledge such as identification thinking and medication experience in the form of“oral transmission and clinical instruction,”so that the academic postgraduates of Chinese medicine can understand the holistic view of the correspondence between heaven and man,the methodology of identification and treatment,and the internal logic of rationale,methodology,prescription and medicine in the clinical diagnosis and treatment.This kind of transmission not only strengthens the students’basic clinical skills of combining the four diagnoses and analyzing the evidence,but also fosters their academic innovation ability of applying classical theories to solve complex clinical problems through the in-depth analysis of typical medical cases.In this paper,we discuss the significance of teacher-training education in the training of academic postgraduates in Chinese medicine,and propose an optimization path for the reference of higher education in Chinese medicine.
基金National Natural Science Foundation of China(Project No.:82260928)Yunnan Province Basic Research Special Key Project(Project No.:202301AS070076)+4 种基金Yunnan Province High-level Science and Technology Talents and Innovation Team Selection Special Project(Project No.:202305AS350007)Research on the Construction of a Course Ideological and Political Education System and Evaluation Framework for the“Traditional Chinese Medicine Internal Medicine”Course(Project No.:2025J0459)Open Research Fund Program of Yunnan Key Laboratory of Integrated Traditional Chinese(Project No.:CWCD2023-002,CWCD2023-003&CWCD2023-009)Western Medicine for Chronic Disease in Prevention and Treatment Yunnan 047 Key Laboratory of Yi Dai Medicine and Yi Medicine(Project No.:2024SS24047)Yunnan 025 Key Laboratory of Yi Dai Medicine and Yi Medicine(Project No.:2024SS24025)。
文摘Interdisciplinary Integrated Teaching is based on constructivist learning theory,systems theory,and collaborative learning theory,emphasising the comprehensive nature of knowledge and its contextual application.Constructivism holds that learning is a process of constructing personal cognition through the integration of knowledge from different fields,while systems theory emphasises that the diagnosis and treatment of complex diseases such as RA require a multidisciplinary collaborative perspective.Collaborative learning theory supports the cultivation of students’comprehensive abilities and problem-solving skills through teamwork.RA is a chronic,systemic autoimmune disease involving multiple organ systems and complex management strategies.Interdisciplinary integrated teaching integrates disciplines such as rheumatology and immunology,imaging,and pharmacy to help students understand the pathophysiological mechanisms,diagnostic criteria,treatment protocols,and patient management of RA,thereby enhancing their ability to address complex diseases.
基金funded by Complement Public Benefit Research Foundation of state forestry administration,P.R.China
文摘Exponential nitrogen(N) loading approach has been used to optimize seedling growth in container seedling production. However, the response of seedling growth to N loading and optimal N loading rates are species-dependent. There is a lack of information on optimal N loading in container production of Australian Blackwood(Acacia melanoxylon) seedlings. In this study, 7 exponential N loading at rates of 0, 50, 100, 200, 300, 400, and 600 mg N seedling-1, respectively, were applied at the week 3, 6, 9, 12 and 14 after transplanting to determine optimal loading approach based on seedling height, root collar diameter(RCD), biomass accumulation and N uptake in tissue-cultured Australian Blackwood(A. melanoxylon) seedlings. Seedlings did not respond to N loading 3 wk after transplanting, then the accumulative addition of N loading for improved RCD and seedling height was 12.99 and 28.02 mg N seedlings-1 in the 100 N and 400 N treatment 6 wk after transplanting, respectively, and on 9 and 12 wk, that for improved seedling growth was 63.64 and 400 mg N seedling-1 in the 200 N and 400 N treatment, respectively. Vector diagnosis of final biomass and N status indicated that the dose of 100 and 400 mg N seedling-1 was characterized to be "deficient" and "optimum" dose of exponential N loading for Blackwood seedlings. These conclusions promise to figure out a precise fertilization regime for Blackwood seedlings and the demonstration of dynamic seedling performance could be used for other tree species.
文摘Soil erosion in the Three-River Headwaters Region(TRHR)of the Qinghai-Tibet Plateau in China has a significant impact on local economic development and ecological environment.Vegetation and precipitation are considered to be the main factors for the variation in soil erosion.However,it is a big challenge to analyze the impacts of precipitation and vegetation respectively as well as their combined effects on soil erosion from the pixel scale.To assess the influences of vegetation and precipitation on the variation of soil erosion from 2005 to 2015,we employed the Revised Universal Soil Loss Equation(RUSLE)model to evaluate soil erosion in the TRHR,and then developed a method using the Logarithmic Mean Divisia Index model(LMDI)which can exponentially decompose the influencing factors,to calculate the contribution values of the vegetation cover factor(C factor)and the rainfall erosivity factor(R factor)to the variation of soil erosion from the pixel scale.In general,soil erosion in the TRHR was alleviated from 2005 to 2015,of which about 54.95%of the area where soil erosion decreased was caused by the combined effects of the C factor and the R factor,and 41.31%was caused by the change in the R factor.There were relatively few areas with increased soil erosion modulus,of which 64.10%of the area where soil erosion increased was caused by the change in the C factor,and 23.88%was caused by the combined effects of the C factor and the R factor.Therefore,the combined effects of the C factor and the R factor were regarded as the main driving force for the decrease of soil erosion,while the C factor was the dominant factor for the increase of soil erosion.The area with decreased soil erosion caused by the C factor(12.10×10^3 km^2)was larger than the area with increased soil erosion caused by the C factor(8.30×10^3 km^2),which indicated that vegetation had a positive effect on soil erosion.This study generally put forward a new method for quantitative assessment of the impacts of the influencing factors on soil erosion,and also provided a scientific basis for the regional control of soil erosion.
文摘Objective The aim of this study was to evaluate the impact of the revised Chinese National Standard GB26878-2011 ＇Iodine Content in Edible Salt＇ on the iodine status among the Chinese population. Methods In 2011 and 2014, the probability proportionate to size sampling（PPS） was used in each Chinese province to obtain the representative data. In each sampling unit, school children aged 8-10 years and pregnant women were selected. Key indicators included urinary iodine concentration（UIC）, thyroid volume（TV）, and the iodine content in edible household salt. Results The median urinary iodine concentration（MUIC） decreased between 2011 and 2014 from 238.6 to 197.9 μg/L in school-age children. The number of provinces with iodine excess decreased to zero. The proportion of children whose UIC was 〉 300 μg/L was 18.8% and decreased to 11% compared with 29.8% in 2011. There was no significant difference in UIC 〈 50 μg/L between 2014（4.3%） and 2011（3.7%）（P 〉 0.05）. The MUIC among pregnant women in 2014 was more concentrated between 110 and 230 μg/L. The goiter rate among children aged 8-10 years was unchanged, both the goiter rate of 2011 and 2014 remaining below 5%, in view of the sustainable elimination of iodine deficiency disorders. Conclusion The National Standard GB26878-2011 ＇Iodine Content in Edible Salt＇ that was introduced in March 2012 resulted in an overall improvement in iodine status, reducing the risk of excessive iodine intake in the Chinese population.
文摘Ca-bentonite can be converted into zeolites A through hydrothermal alkaline treatment by varying the synthetic parameters. This study focuses on the effect of initial Si/Al molar ratio, NaOH concentration on the type of formed zeolite A. The Ca-bentonite (China, Fuxin)were mixed with an aqueous NaOH solution, Al(OH)3 powder and hydrothermally treated at about 90 ℃,12 h. Different types of zeolites (zeolite X, P, and A),sodalite were synthesized after the treatment. Zeolites were characterized and quantified by means of XRD and SEM analysis. Zeolite A predominantly formed with 0.5≤Si/Al≤2.0 was produced and zeolite X, P formed with Si/Al>2.0 under the 2.2mol/LNaOH concentration; Sodalite was also formed under high NaOH molarities. Shape of zeolite A is show the cube by the SEM micrograph.
基金supported by Chongqing Research and Frontier Technology(cstc2020jcyj-msxmX0537)the State Key Laboratory of Drug Research(SIMM1903KF-14)Fundamental Research Funds for the Central Universities(No.2020CDJ-LHZZ-006)。
文摘Fourteen new geranyl phenyl ethers(1–14)along with three known compounds(15–17)were isolated from Illicium micranthum,and their structures were elucidated by comprehensive spectroscopic methods.Illimicranins A–H(1–8)were characterized as geranyl vanillin ethers,while 9 and 10 were dimethyl acetal derivatives.Illimicranins I and J(11 and 12)were rare geranyl isoeugenol ethers.Illimicranins K and L(13 and 14)represented the first example of geranyl guaiacylacetone ether and geranyl zingerone ether,respectively.Compounds 1,2 and 15 exhibited anti-HBV(hepatitis B virus)activity against HBsAg(hepatitis B surface antigen)and HBeAg(hepatitis B e antigen)secretion,and HBV DNA replication.
