Background:At a global level,the COVID-19 disease outbreak has had a major impact on health services and has induced disruption in routine care of health institutions,exposing cancer patients to severe risks.To provid...Background:At a global level,the COVID-19 disease outbreak has had a major impact on health services and has induced disruption in routine care of health institutions,exposing cancer patients to severe risks.To provide unin-terrupted tumor treatment throughout a pandemic lockdown is a major obstacle.Coronavirus disease(COVID-19)and its causative virus,SARS-CoV-2,stance considerable challenges for the management of oncology patients.COVID-19 presents particularly severe respiratory and systemic infection in aging and immunosuppressed indi-viduals,including patients with cancer.Objective:In the present review,we focused on emergent evidence from cancer sufferers that have been con-taminated with COVID-19 and cancer patients who were at higher risk of severe COVID-19,and indicates that anticancer treatment may either rise COVID-19 susceptibility or have a duple therapeutic impact on cancer as well as COVID-19;moreover,how SARS-CoV-2 infection impacts cancer cells.Also,to assess the global effect of the COVID-19 disease outbreak on cancer and its treatment.Methods:A literature survey was conducted using PubMed,Web of Science(WOS),Embase,Cochrane Library,China National Knowledge Infrastructure(CNKI),and VIral Protein domain DataBase(VIP DB)between Dec 1,2019 and Sep 23,2021,for studies on anticancer treatments in patients with COVID-19.The characteristics of the patients,treatment types,mortality,and other additional outcomes were extracted and pooled for synthesis.Results:This disease has a huge effect on sufferers who have cancer(s).Sufferers of COVID-19 have a greater percentage of tumor diagnoses than the rest of the population.Likewise,cancer and highest proportion is lung cancer sufferers are more susceptible to COVID-19 constriction than the rest of the population.Conclusion:Sufferers who have both COVID-19 and tumor have a considerably elevated death risk than single COVID-19 positive patients overall.During the COVID-19 pandemic,there was a reduction in the screening of cancer and detection,and also deferral of routine therapies,which may contribute to an increase in cancer mortality there in future.展开更多
文摘Background:At a global level,the COVID-19 disease outbreak has had a major impact on health services and has induced disruption in routine care of health institutions,exposing cancer patients to severe risks.To provide unin-terrupted tumor treatment throughout a pandemic lockdown is a major obstacle.Coronavirus disease(COVID-19)and its causative virus,SARS-CoV-2,stance considerable challenges for the management of oncology patients.COVID-19 presents particularly severe respiratory and systemic infection in aging and immunosuppressed indi-viduals,including patients with cancer.Objective:In the present review,we focused on emergent evidence from cancer sufferers that have been con-taminated with COVID-19 and cancer patients who were at higher risk of severe COVID-19,and indicates that anticancer treatment may either rise COVID-19 susceptibility or have a duple therapeutic impact on cancer as well as COVID-19;moreover,how SARS-CoV-2 infection impacts cancer cells.Also,to assess the global effect of the COVID-19 disease outbreak on cancer and its treatment.Methods:A literature survey was conducted using PubMed,Web of Science(WOS),Embase,Cochrane Library,China National Knowledge Infrastructure(CNKI),and VIral Protein domain DataBase(VIP DB)between Dec 1,2019 and Sep 23,2021,for studies on anticancer treatments in patients with COVID-19.The characteristics of the patients,treatment types,mortality,and other additional outcomes were extracted and pooled for synthesis.Results:This disease has a huge effect on sufferers who have cancer(s).Sufferers of COVID-19 have a greater percentage of tumor diagnoses than the rest of the population.Likewise,cancer and highest proportion is lung cancer sufferers are more susceptible to COVID-19 constriction than the rest of the population.Conclusion:Sufferers who have both COVID-19 and tumor have a considerably elevated death risk than single COVID-19 positive patients overall.During the COVID-19 pandemic,there was a reduction in the screening of cancer and detection,and also deferral of routine therapies,which may contribute to an increase in cancer mortality there in future.
