Carbon fiber-reinforced carbon and silicon carbide(C_(f)/C-SiC)composites have garnered substantial attention because of their superior mechanical properties at elevated temperatures.In the present work,the tribologic...Carbon fiber-reinforced carbon and silicon carbide(C_(f)/C-SiC)composites have garnered substantial attention because of their superior mechanical properties at elevated temperatures.In the present work,the tribological properties of 2.5D C_(f)/C-SiC against silicon nitride under dry friction over a wide temperature range,ranging from room temperature(RT)to 800℃,are studied with a pin-on-disc tribometer,and the microstructure is characterized via a variety of methods.The results underscore that 600℃ marks a pivotal juncture where the tribological properties of C_(f)/C-SiC undergo a notable shift.Below 600℃,the friction coefficient clearly increases with increasing temperature,paired with minimal wear.For this temperature range,the main wear mechanisms are minor oxidation wear and slight abrasive wear.In contrast,above 600℃,a slightly lower,fluctuating plateau is observed in the friction coefficient.This is attributed to the accumulation of wear debris,the cyclical formation and breakdown of the friction film,and the softening of the friction surface.For temperatures above 600℃,the wear mechanism transitions into a state characterized by the concurrent presence of adhesive wear,abrasive wear,and severe oxidative wear.This study provides an in-depth understanding of the tribological behavior and wear mechanism of C_(f)/C-SiC at elevated temperatures.展开更多
The application of traditional Chinese medicine(TCM)has made great contributions to the fight against the epidemic of coronavirus disease-2019(COVID-19).Despite the remarkable therapeutic effects of TCM,the molecular ...The application of traditional Chinese medicine(TCM)has made great contributions to the fight against the epidemic of coronavirus disease-2019(COVID-19).Despite the remarkable therapeutic effects of TCM,the molecular mechanisms of TCM formulae inhibiting COVID-19 are still not fully understood.Here,we cφm-bined the automated high throughput sequencing-based high throughput screening(HTS^(2))assay with bioinformatics and computer-aided drug design(CADD)to investigate the molecular mechanisms of TCM-mediated therapeutic effects on COVID-19-related cytokine storm(Fig.1a).展开更多
基金support from the National Natural Science Foundation of China(No.52275207)the Natural Science Foundation of Tianjin City(No.22JCZDJC00050).
文摘Carbon fiber-reinforced carbon and silicon carbide(C_(f)/C-SiC)composites have garnered substantial attention because of their superior mechanical properties at elevated temperatures.In the present work,the tribological properties of 2.5D C_(f)/C-SiC against silicon nitride under dry friction over a wide temperature range,ranging from room temperature(RT)to 800℃,are studied with a pin-on-disc tribometer,and the microstructure is characterized via a variety of methods.The results underscore that 600℃ marks a pivotal juncture where the tribological properties of C_(f)/C-SiC undergo a notable shift.Below 600℃,the friction coefficient clearly increases with increasing temperature,paired with minimal wear.For this temperature range,the main wear mechanisms are minor oxidation wear and slight abrasive wear.In contrast,above 600℃,a slightly lower,fluctuating plateau is observed in the friction coefficient.This is attributed to the accumulation of wear debris,the cyclical formation and breakdown of the friction film,and the softening of the friction surface.For temperatures above 600℃,the wear mechanism transitions into a state characterized by the concurrent presence of adhesive wear,abrasive wear,and severe oxidative wear.This study provides an in-depth understanding of the tribological behavior and wear mechanism of C_(f)/C-SiC at elevated temperatures.
基金supported by the National Natural Science Foundation of China(81673460)Sichuan Youth Science and Technology Innovation Research Team of Experimental Formulology(2020JDTD0022)。
文摘The application of traditional Chinese medicine(TCM)has made great contributions to the fight against the epidemic of coronavirus disease-2019(COVID-19).Despite the remarkable therapeutic effects of TCM,the molecular mechanisms of TCM formulae inhibiting COVID-19 are still not fully understood.Here,we cφm-bined the automated high throughput sequencing-based high throughput screening(HTS^(2))assay with bioinformatics and computer-aided drug design(CADD)to investigate the molecular mechanisms of TCM-mediated therapeutic effects on COVID-19-related cytokine storm(Fig.1a).
