Objective:To investigate the association of body mass index(BMI),waist circumference(WC),and waist-to-height ratio(WHtR)with the long-term prognosis of ST-elevation myocardial infarction(STEMI)patients and to determin...Objective:To investigate the association of body mass index(BMI),waist circumference(WC),and waist-to-height ratio(WHtR)with the long-term prognosis of ST-elevation myocardial infarction(STEMI)patients and to determine whether the combination of obesity indices can be used for risk stratification.Method:A multifactorial Cox regression analysis was performed using 3-year follow-up data from 220 STEMI patients to explore the relationship between obesity indicators and major adverse cardiovascular events(MACEs).The incidence of MACEs was also compared by combining BMI and WHtR.Results:WC was found to reduce the risk of MACEs within 25 months after myocardial infarction[hazard ratio(HR)=0.95,95%confidence interval(CI)=0.92-0.98,P<0.001].However,this effect was not significant beyond 25 months(HR=0.98,95%CI=0.97-1.07,P=0.49).Neither BMI nor WHtR were significantly associated with the risk of MACEs.The incidence of MACEs was highest in patients with low body weight(BMI<18.5 kg/m^(2))and WHtR>0.5,and lowest in obese patients(BMI≥28 kg/m^(2))with WHtR>0.5.Conclusions:BMI,WC,and WHtR were not significantly associated with the long-term prognosis of STEMI patients.However,the combination of BMI and WHtR can be useful for further stratifying patient risk.展开更多
基金National Natural Science Foundation of China(Grant/Award Number:81970304)Tianjin Municipal Science and Technology Commission(Grant/Award Numbers:18ZXZNSY00290 and 19JCQNJC11500).
文摘Objective:To investigate the association of body mass index(BMI),waist circumference(WC),and waist-to-height ratio(WHtR)with the long-term prognosis of ST-elevation myocardial infarction(STEMI)patients and to determine whether the combination of obesity indices can be used for risk stratification.Method:A multifactorial Cox regression analysis was performed using 3-year follow-up data from 220 STEMI patients to explore the relationship between obesity indicators and major adverse cardiovascular events(MACEs).The incidence of MACEs was also compared by combining BMI and WHtR.Results:WC was found to reduce the risk of MACEs within 25 months after myocardial infarction[hazard ratio(HR)=0.95,95%confidence interval(CI)=0.92-0.98,P<0.001].However,this effect was not significant beyond 25 months(HR=0.98,95%CI=0.97-1.07,P=0.49).Neither BMI nor WHtR were significantly associated with the risk of MACEs.The incidence of MACEs was highest in patients with low body weight(BMI<18.5 kg/m^(2))and WHtR>0.5,and lowest in obese patients(BMI≥28 kg/m^(2))with WHtR>0.5.Conclusions:BMI,WC,and WHtR were not significantly associated with the long-term prognosis of STEMI patients.However,the combination of BMI and WHtR can be useful for further stratifying patient risk.
