The appearing of microbial lineages carrying multiple dangerous loci are results from the extensive use of antibiotics and has brought a huge increase in the infections-derived morbidity and mortality, which is critic...The appearing of microbial lineages carrying multiple dangerous loci are results from the extensive use of antibiotics and has brought a huge increase in the infections-derived morbidity and mortality, which is critical in the hospital setting. Etiologic agents of these non easily tractable infections include bacteria, such as the genus Staphylococcus, but also fungi and virus. Alterations in the immune system allow these organisms to invade and affect the functionality of any tissue, organ or system of the human being. Pulmonary infection occurs as result of deficient lung systemic defence mechanisms which could be altered by medical treatments or by environmental factors. The infective agents commonly gain access to the lung by air, but also by blood or lymphatic system. Staphylococcus aureus strains that share antibiotic resistance and virulence factors represent the aetiological agent responsible of many cases of bacterial pneumonia, thoracic surgery postoperative infections, and diverse tissue infections, resulting in significant disease and morbidity in recipient patients after lung transplantation. The control and treatment of Staphylococcus infections, especially methicillin resistant strains, need for developing reliable and rapid methods of detection and characterization of these microorganisms. Nowadays, new insights into the diagnostic and epidemiology of MRSA and other pathogenic staphylococci have been developed employing molecular methods. This has meant an important advance in the diagnostic and treatment plans of such infective bacteria.展开更多
We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recov...We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recovered from catheter was surprisingly identified as S. hominis by sequencing of the 16S ribosomal gene. The S. hominis isolate, which is not often associated with infections in dialysis patients, was resistant to methicillin, being mecA positive, and to daptomycin. The patient was successfully treated with vancomycin together with the catheter retirement.展开更多
Among the many sources of plastic contamination,greenhouse agriculture is a major contributor due to its intensive use of plastic materials.This study examines plastic waste in one of the world's leading greenhous...Among the many sources of plastic contamination,greenhouse agriculture is a major contributor due to its intensive use of plastic materials.This study examines plastic waste in one of the world's leading greenhouse farming regions.The research included both abiotic(soil,freshwater,seawater,and air)and biotic compartments(invertebrates,herbivores,fish and predators)as well as the presence of bacterial and fungal pathogens colonizing agricultural plastics.Plastics were identified in all sampled compartments,including the nearshore seawater.The highest concentrations were recorded along the coastline,where 1397 plastic items representing 15 different polymers were found with a median concentration of 1.92(1.732.13)items/m^(2) or 3.05(2.293.81)g/m^(2),the boundaries representing interquartile ranges.Most of the polymers identified across all compartments matched those found in agricultural operations in terms of morphology,type,and colour.Notably,high plastic concentration appeared in protected areas,indicating that legal protection alone does not prevent pollution.Greenhouse plastics were especially prevalent in the protected zones near the greenhouse area,rather than in the nearby urban zones,which can be explained by the proximity of agricultural exploitations.We estimated that approximately 290 kg of plastic,including 80 kg of polyethylene,were dispersed along the coast,a figure representing about one-tenth of the plastic waste generated annually in the production zone.Our results also revealed that agricultural plastic waste may act as vector and reservoir of bacterial and fungal pathogens,promoting their spread even into protected environments.展开更多
文摘The appearing of microbial lineages carrying multiple dangerous loci are results from the extensive use of antibiotics and has brought a huge increase in the infections-derived morbidity and mortality, which is critical in the hospital setting. Etiologic agents of these non easily tractable infections include bacteria, such as the genus Staphylococcus, but also fungi and virus. Alterations in the immune system allow these organisms to invade and affect the functionality of any tissue, organ or system of the human being. Pulmonary infection occurs as result of deficient lung systemic defence mechanisms which could be altered by medical treatments or by environmental factors. The infective agents commonly gain access to the lung by air, but also by blood or lymphatic system. Staphylococcus aureus strains that share antibiotic resistance and virulence factors represent the aetiological agent responsible of many cases of bacterial pneumonia, thoracic surgery postoperative infections, and diverse tissue infections, resulting in significant disease and morbidity in recipient patients after lung transplantation. The control and treatment of Staphylococcus infections, especially methicillin resistant strains, need for developing reliable and rapid methods of detection and characterization of these microorganisms. Nowadays, new insights into the diagnostic and epidemiology of MRSA and other pathogenic staphylococci have been developed employing molecular methods. This has meant an important advance in the diagnostic and treatment plans of such infective bacteria.
基金partially supported by grant FIS10/00125 from INSTITUTO DE SALUD CARLOSIII(Spanish Health Ministry)to S.M.-A.
文摘We report a case of a haemodialysis patient that presented a catheter-related bacteraemia caused by a Coagulase negative Staphylococcus. With the utilization of molecular biology techniques the bacterial isolate recovered from catheter was surprisingly identified as S. hominis by sequencing of the 16S ribosomal gene. The S. hominis isolate, which is not often associated with infections in dialysis patients, was resistant to methicillin, being mecA positive, and to daptomycin. The patient was successfully treated with vancomycin together with the catheter retirement.
基金support provided by the Spanish Government,Ministry of Science,grants PLEC2021007693 and PID2020-113769RB-C21/C22.
文摘Among the many sources of plastic contamination,greenhouse agriculture is a major contributor due to its intensive use of plastic materials.This study examines plastic waste in one of the world's leading greenhouse farming regions.The research included both abiotic(soil,freshwater,seawater,and air)and biotic compartments(invertebrates,herbivores,fish and predators)as well as the presence of bacterial and fungal pathogens colonizing agricultural plastics.Plastics were identified in all sampled compartments,including the nearshore seawater.The highest concentrations were recorded along the coastline,where 1397 plastic items representing 15 different polymers were found with a median concentration of 1.92(1.732.13)items/m^(2) or 3.05(2.293.81)g/m^(2),the boundaries representing interquartile ranges.Most of the polymers identified across all compartments matched those found in agricultural operations in terms of morphology,type,and colour.Notably,high plastic concentration appeared in protected areas,indicating that legal protection alone does not prevent pollution.Greenhouse plastics were especially prevalent in the protected zones near the greenhouse area,rather than in the nearby urban zones,which can be explained by the proximity of agricultural exploitations.We estimated that approximately 290 kg of plastic,including 80 kg of polyethylene,were dispersed along the coast,a figure representing about one-tenth of the plastic waste generated annually in the production zone.Our results also revealed that agricultural plastic waste may act as vector and reservoir of bacterial and fungal pathogens,promoting their spread even into protected environments.
