OBJECTIVE:To evaluate the efficacy of electroacupuncture(EA)intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass(CPB).METHODS:Eight ...OBJECTIVE:To evaluate the efficacy of electroacupuncture(EA)intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass(CPB).METHODS:Eight databases,including Pub Med,Embase,the Cochrane Library,Web of Science,Chinese Bio Medical Literature Database,China National Knowledge Infrastructure Database,Wanfang Data,China Science and Technology Journal Database,and two clinical trial registries,were searched.All randomized controlled trials(RCTs)related to EA intervention in cardiac surgery with CPB were collected.Based on the inclusion and exclusion criteria,two researchers independently screened articles and extracted data.After the quality evaluation,RevMan 5.3 software was used for analysis.RESULTS:Fourteen RCTs involving 836 patients were included.Compared with the control treatment,EA significantly increased the incidence of cardiac automatic rebeat after aortic unclamping[relative risk(RR)=1.15,95%confidence interval(CI)(1.01,1.31),P<0.05;moderate].Twenty-four hours after aortic unclamping,EA significantly increased the superoxide dismutase[standardized mean difference(SMD)=0.96,95%CI(0.32,1.61),P<0.05;low],and interleukin(IL)-2[SMD=1.33,95%CI(0.19,2.47),P<0.05;very low]expression levels and decreased the malondialdehyde[SMD=-1.62,95%CI(-2.15,-1.09),P<0.05;moderate],tumour necrosis factor-α[SMD=-1.28,95%CI(-2.37,-0.19),P<0.05;moderate],and cardiac troponin I[SMD=-1.09,95%CI(-1.85,-0.32),P<0.05;low]expression levels as well as the inotrope scores[SMD=-0.77,95%CI(-1.22,-0.31),P<0.05;high].There was no difference in IL-6 and IL-10 expression levels.The amount of intraoperative sedative[SMD=-0.31,95%CI(-0.54,-0.09),P<0.05;moderate]and opioid analgesic[SMD=-0.96,95%CI(-1.53,-0.38),P<0.05;low]medication was significantly lower in the EA group than in the control group.Moreover,the postoperative tracheal intubation time[SMD=-0.92,95%CI(-1.40,-0.45),P<0.05;low]and intensive care unit stay[SMD=-1.71,95%CI(-3.06,-0.36),P<0.05;low]were significantly shorter in the EA group than in the control group.There were no differences in the time to get out of bed for the first time,total days of antibiotic use after surgery,or postoperative hospital stay.No adverse reactions related to EA were reported in any of the included studies.CONCLUSIONS:In cardiac surgery with CPB,EA may be a safe and effective strategy to reduce myocardial ischaemia-reperfusion injury and speed up the recovery of patients after surgery.These findings must be interpreted with caution,as most of the evidence was of low or moderate quality.More RCTs with larger sample sizes and higher quality are needed to provide more convincing evidence.展开更多
目的通过Meta分析评价超声和磁共振成像(magnetic resonance imaging,MRI)诊断膝骨关节炎(knee osteoarthritis,KOA)的价值。方法对多个数据库中关于KOA超声和MRI诊断的文献进行筛选、数据提取及研究质量评估,最终纳入14篇文献,涉及161...目的通过Meta分析评价超声和磁共振成像(magnetic resonance imaging,MRI)诊断膝骨关节炎(knee osteoarthritis,KOA)的价值。方法对多个数据库中关于KOA超声和MRI诊断的文献进行筛选、数据提取及研究质量评估,最终纳入14篇文献,涉及1613例患者。对数据进行Meta分析,全面评估超声和MRI对KOA诊断的有效性。结果纳入研究均以关节镜或手术病理结果作为诊断的金标准。超声在诊断KOA方面的合并敏感度、特异性和诊断比值比分别为0.79、0.82和20.30,而受试者操作特征曲线下面积(area under the curve,AUC)值为0.89。MRI诊断KOA的合并敏感度、特异性和诊断比值比分别为0.88、0.85和42.35,其AUC值为0.92。结论超声和MRI在KOA的诊断中均展现出较高的准确性,其中MRI准确性更高。展开更多
基于语音识别设计了针对脑瘫患儿的数字语音训练系统。应用人机交互(HRI)技术与仿生机械手动作控制相结合达到提升脑瘫(CP)康复训练效果的目的。该系统中控制器采用Arduino MEGA 2560为主控制器,显示屏LCD1602作为人机交互数据显示界面...基于语音识别设计了针对脑瘫患儿的数字语音训练系统。应用人机交互(HRI)技术与仿生机械手动作控制相结合达到提升脑瘫(CP)康复训练效果的目的。该系统中控制器采用Arduino MEGA 2560为主控制器,显示屏LCD1602作为人机交互数据显示界面,通过LD3320语音芯片实现人机语音交互功能。人机交互功能是通过Labview环境展开,可实现人、机器人的手势与动作的实时交互训练与评价。该系统可训练脑瘫患者反应能力、语言表述能力以及认识手势动作数字动作能力,为提升脑瘫康复训练系统提供关键技术。展开更多
基金the National Natural Science Foundation of China:Mechanism of Protective Effect of Acupoint Preconditioning on Myocardial Mitochondria and Energy Metabolism in Rats with Bupivacaine Toxicity(No.81760892)。
文摘OBJECTIVE:To evaluate the efficacy of electroacupuncture(EA)intervention on myocardial protection and postoperative rehabilitation in patients undergoing cardiac surgery with cardiopulmonary bypass(CPB).METHODS:Eight databases,including Pub Med,Embase,the Cochrane Library,Web of Science,Chinese Bio Medical Literature Database,China National Knowledge Infrastructure Database,Wanfang Data,China Science and Technology Journal Database,and two clinical trial registries,were searched.All randomized controlled trials(RCTs)related to EA intervention in cardiac surgery with CPB were collected.Based on the inclusion and exclusion criteria,two researchers independently screened articles and extracted data.After the quality evaluation,RevMan 5.3 software was used for analysis.RESULTS:Fourteen RCTs involving 836 patients were included.Compared with the control treatment,EA significantly increased the incidence of cardiac automatic rebeat after aortic unclamping[relative risk(RR)=1.15,95%confidence interval(CI)(1.01,1.31),P<0.05;moderate].Twenty-four hours after aortic unclamping,EA significantly increased the superoxide dismutase[standardized mean difference(SMD)=0.96,95%CI(0.32,1.61),P<0.05;low],and interleukin(IL)-2[SMD=1.33,95%CI(0.19,2.47),P<0.05;very low]expression levels and decreased the malondialdehyde[SMD=-1.62,95%CI(-2.15,-1.09),P<0.05;moderate],tumour necrosis factor-α[SMD=-1.28,95%CI(-2.37,-0.19),P<0.05;moderate],and cardiac troponin I[SMD=-1.09,95%CI(-1.85,-0.32),P<0.05;low]expression levels as well as the inotrope scores[SMD=-0.77,95%CI(-1.22,-0.31),P<0.05;high].There was no difference in IL-6 and IL-10 expression levels.The amount of intraoperative sedative[SMD=-0.31,95%CI(-0.54,-0.09),P<0.05;moderate]and opioid analgesic[SMD=-0.96,95%CI(-1.53,-0.38),P<0.05;low]medication was significantly lower in the EA group than in the control group.Moreover,the postoperative tracheal intubation time[SMD=-0.92,95%CI(-1.40,-0.45),P<0.05;low]and intensive care unit stay[SMD=-1.71,95%CI(-3.06,-0.36),P<0.05;low]were significantly shorter in the EA group than in the control group.There were no differences in the time to get out of bed for the first time,total days of antibiotic use after surgery,or postoperative hospital stay.No adverse reactions related to EA were reported in any of the included studies.CONCLUSIONS:In cardiac surgery with CPB,EA may be a safe and effective strategy to reduce myocardial ischaemia-reperfusion injury and speed up the recovery of patients after surgery.These findings must be interpreted with caution,as most of the evidence was of low or moderate quality.More RCTs with larger sample sizes and higher quality are needed to provide more convincing evidence.
文摘目的通过Meta分析评价超声和磁共振成像(magnetic resonance imaging,MRI)诊断膝骨关节炎(knee osteoarthritis,KOA)的价值。方法对多个数据库中关于KOA超声和MRI诊断的文献进行筛选、数据提取及研究质量评估,最终纳入14篇文献,涉及1613例患者。对数据进行Meta分析,全面评估超声和MRI对KOA诊断的有效性。结果纳入研究均以关节镜或手术病理结果作为诊断的金标准。超声在诊断KOA方面的合并敏感度、特异性和诊断比值比分别为0.79、0.82和20.30,而受试者操作特征曲线下面积(area under the curve,AUC)值为0.89。MRI诊断KOA的合并敏感度、特异性和诊断比值比分别为0.88、0.85和42.35,其AUC值为0.92。结论超声和MRI在KOA的诊断中均展现出较高的准确性,其中MRI准确性更高。
文摘基于语音识别设计了针对脑瘫患儿的数字语音训练系统。应用人机交互(HRI)技术与仿生机械手动作控制相结合达到提升脑瘫(CP)康复训练效果的目的。该系统中控制器采用Arduino MEGA 2560为主控制器,显示屏LCD1602作为人机交互数据显示界面,通过LD3320语音芯片实现人机语音交互功能。人机交互功能是通过Labview环境展开,可实现人、机器人的手势与动作的实时交互训练与评价。该系统可训练脑瘫患者反应能力、语言表述能力以及认识手势动作数字动作能力,为提升脑瘫康复训练系统提供关键技术。
