OBJECTIVE:To investigate the clinical effects of modified Dachengqi Tang(DCQT) on promoting gastrointestinal motility in post-operative esophageal cancer patients.METHODS:Sixty postoperative esophageal cancer patients...OBJECTIVE:To investigate the clinical effects of modified Dachengqi Tang(DCQT) on promoting gastrointestinal motility in post-operative esophageal cancer patients.METHODS:Sixty postoperative esophageal cancer patients were enrolled and randomly assigned to the modified treatment group or the control group(30 patients in each group).Patients in the treatment group were given DCQT made from decocted herbs and administered via nasojejunal tube at a dosage of 150 mL.Gastrointestinal motility was assessed by recording time for recovery of bowel sounds,flatus,defecation,and the total amount of gastric drainage during the first three postoperative days.Plasma motilin(MTL) and vasoactive intestinal peptide(VIP) were measured one hour before and three days after surgery.RESULTS:Compared with the control group,the times to first bowel sound,flatus,and defecation were significantly shorter and there was less gastric drainage in the treatment group(P < 0.01,P < 0.01,P < 0.01,and P < 0.05,respectively).In the treatment group,postoperative plasma MTL was significantly higher(P < 0.01) and VIP was significantly lower than those in the control group(P < 0.05).There was no difference found in either MTL or VIP from before to after operation in the treatment group(P > 0.05).MTL was significantly lower and VIP was higher postoperatively in the control group,compared to before surgery(P < 0.01).CONCLUSION:Modified DCQT effectively improved decreased gastrointestinal motility in postoperative esophageal cancer patients by increasing MTL and reducing VIP.展开更多
阐述衔接视角下初高中英语读写学习进阶探索的必要性及高中英语读写教学现状和归因。基于衔接视角,以“学生连贯发展、教师协同发展、读写结构化发展”为目标,以PACE教学模式为核心基础,以X作为学习进阶变量,构建初高中整体发展的英语...阐述衔接视角下初高中英语读写学习进阶探索的必要性及高中英语读写教学现状和归因。基于衔接视角,以“学生连贯发展、教师协同发展、读写结构化发展”为目标,以PACE教学模式为核心基础,以X作为学习进阶变量,构建初高中整体发展的英语读写结合X-PACE教学模型:准备与呈现(Preparation and Presentation)→注意与分析(Attention and Analysis)→共建与创新(Co-construction and Creation)→拓展与评价(Extension and Evaluation),探索如何在初高中不同阶段和高中不同年级支持和增强学生对同一主题的理解,培养学生逐步深入思考一个主题的能力,从而实现有意义的读写结合学习进程。展开更多
目的对术后患者低氧血症风险预测模型进行归纳总结,为临床护理实践及未来术后患者低氧血症风险预测模型的研究提供借鉴。方法计算机系统检索中国知网、中国生物医学文献数据库、万方数据库、PubMed、Web of Science核心集、Cochrane Lib...目的对术后患者低氧血症风险预测模型进行归纳总结,为临床护理实践及未来术后患者低氧血症风险预测模型的研究提供借鉴。方法计算机系统检索中国知网、中国生物医学文献数据库、万方数据库、PubMed、Web of Science核心集、Cochrane Library、Embase、CINAHL数据库,检索时限均为建库至2024年1月31日。由2名研究者独立筛选文献并对纳入文献进行数据提取、整合分析和偏倚风险评价。结果共纳入17篇文献,涉及17个模型。研究人群以成年人为主,结局事件发生率为2.40%~49.30%。建模方法包括Logistic回归、决策树算法;模型展示形式分为风险评分公式、列线图、决策树形图以及网页计算器4类;出现频次最高的5项预测因子为体重指数、年龄、合并症、术中体外循环时间和术前白细胞计数;16个模型报告了受试者工作特征曲线下面积,为0.667~0.916;17个研究均存在一定的偏倚风险。结论现有研究构建的术后患者低氧血症风险预测模型的性能较好,但整体偏倚风险水平较高;未来可参照预测模型偏倚风险评估清单规范模型构建过程,建立偏倚风险低、临床实用性强的模型。展开更多
基金the Administration of Shandong Provincial Traditional Chinese Medicine,China,No.2009-166
文摘OBJECTIVE:To investigate the clinical effects of modified Dachengqi Tang(DCQT) on promoting gastrointestinal motility in post-operative esophageal cancer patients.METHODS:Sixty postoperative esophageal cancer patients were enrolled and randomly assigned to the modified treatment group or the control group(30 patients in each group).Patients in the treatment group were given DCQT made from decocted herbs and administered via nasojejunal tube at a dosage of 150 mL.Gastrointestinal motility was assessed by recording time for recovery of bowel sounds,flatus,defecation,and the total amount of gastric drainage during the first three postoperative days.Plasma motilin(MTL) and vasoactive intestinal peptide(VIP) were measured one hour before and three days after surgery.RESULTS:Compared with the control group,the times to first bowel sound,flatus,and defecation were significantly shorter and there was less gastric drainage in the treatment group(P < 0.01,P < 0.01,P < 0.01,and P < 0.05,respectively).In the treatment group,postoperative plasma MTL was significantly higher(P < 0.01) and VIP was significantly lower than those in the control group(P < 0.05).There was no difference found in either MTL or VIP from before to after operation in the treatment group(P > 0.05).MTL was significantly lower and VIP was higher postoperatively in the control group,compared to before surgery(P < 0.01).CONCLUSION:Modified DCQT effectively improved decreased gastrointestinal motility in postoperative esophageal cancer patients by increasing MTL and reducing VIP.
文摘阐述衔接视角下初高中英语读写学习进阶探索的必要性及高中英语读写教学现状和归因。基于衔接视角,以“学生连贯发展、教师协同发展、读写结构化发展”为目标,以PACE教学模式为核心基础,以X作为学习进阶变量,构建初高中整体发展的英语读写结合X-PACE教学模型:准备与呈现(Preparation and Presentation)→注意与分析(Attention and Analysis)→共建与创新(Co-construction and Creation)→拓展与评价(Extension and Evaluation),探索如何在初高中不同阶段和高中不同年级支持和增强学生对同一主题的理解,培养学生逐步深入思考一个主题的能力,从而实现有意义的读写结合学习进程。
文摘目的对术后患者低氧血症风险预测模型进行归纳总结,为临床护理实践及未来术后患者低氧血症风险预测模型的研究提供借鉴。方法计算机系统检索中国知网、中国生物医学文献数据库、万方数据库、PubMed、Web of Science核心集、Cochrane Library、Embase、CINAHL数据库,检索时限均为建库至2024年1月31日。由2名研究者独立筛选文献并对纳入文献进行数据提取、整合分析和偏倚风险评价。结果共纳入17篇文献,涉及17个模型。研究人群以成年人为主,结局事件发生率为2.40%~49.30%。建模方法包括Logistic回归、决策树算法;模型展示形式分为风险评分公式、列线图、决策树形图以及网页计算器4类;出现频次最高的5项预测因子为体重指数、年龄、合并症、术中体外循环时间和术前白细胞计数;16个模型报告了受试者工作特征曲线下面积,为0.667~0.916;17个研究均存在一定的偏倚风险。结论现有研究构建的术后患者低氧血症风险预测模型的性能较好,但整体偏倚风险水平较高;未来可参照预测模型偏倚风险评估清单规范模型构建过程,建立偏倚风险低、临床实用性强的模型。
文摘目的探讨《北京市医药分开综合改革》(简称医改)对三甲医院急诊科拥挤现象的影响。方法将2017年4月8日开始实施《北京市医药分开综合改革》作为时间节点,分别将医改前20 d、医改后20 d和医改后21~40 d定义为医改前组、医改中组和医改后组,60 d的观察期内每日在10点、14点、18点进行北京大学第三医院急诊科拥挤度评分(NEDOCS评分),取3个时间点的平均值比较急诊科拥挤现象的变化,并对比NEDOCS评分公式中的关键指标来明确拥挤现象变化的原因。统计分析采用SPSS 25.0统计软件,符合正态分布的计量资料以均数±标准差表示,组间比较采用成组t检验,不符合正态分布的计量资料以四分位数间距表示,组间比较采用U检验。结果医改中组的NEDOCS评分高于医改前组,差异有统计学意义(401.69 vs 339.68,P<0.05),医改后组与医改前组的NEDOCS评分差异无统计学意义(380.83 vs 339.68,P>0.05)。医改中组和医改后组中Rn(机械通气患者数)较医改前组均显著增加(P<0.05)。结论2017年北京市医改后,三甲医院急诊科拥挤现象有所加重,重症患者数量的增加可能是导致急诊科拥挤现象加重的原因。
