Royal jelly(RJ)is rich in various nutrients with multiple health-promoting properties.This study aims to evaluate whether RJ can modulate related metabolite in the natural aging mice.Male C57BL/6J mice drank RJ soluti...Royal jelly(RJ)is rich in various nutrients with multiple health-promoting properties.This study aims to evaluate whether RJ can modulate related metabolite in the natural aging mice.Male C57BL/6J mice drank RJ solution daily for 9 months.Determination of serum lipids and pathological analysis exhibited that triglycerides,serum cholesterol,and low-density lipoprotein cholesterol were decreased by 31.15%,9.96%,and 22.58%,respectively,the morphology of brain nerve cells was also effectively recovered after RJ intervention.Lipidomic analysis showed that RJ could improve the levels of different kinds of lipids in aging mice brain,especially by increasing the content of antioxidant ether ester,and that the ratio of monounsaturated fatty acid to polyunsaturated fatty acid was up by 23.46%,which could alleviate oxidative stress.Moreover,the metabolism of glycerol phospholipids,glycerols,and fatty acids in aging mice could be regulated by RJ.RJ intervention can effectively improve lipid metabolism disorders caused by aging.展开更多
Resection of oral and maxillofacial tumors is often accompanied by the inferior alveolar nerve neurectomy,resulting in abnormal sensation in lower lip.It is generally believed that spontaneous sensory recovery in this...Resection of oral and maxillofacial tumors is often accompanied by the inferior alveolar nerve neurectomy,resulting in abnormal sensation in lower lip.It is generally believed that spontaneous sensory recovery in this nerve injury is difficult.However,during our follow-up,patients with inferior alveolar nerve sacrifice showed different degrees of lower lip sensory recovery.In this study,a prospective cohort study was conducted to demonstrate this phenomenon and analyze the factors influencing sensory recovery.展开更多
The interaction of high energy lepton jets composed of electrons and positrons with background electron–proton plasma is investigated numerically based upon particle-in-cell simulation,focusing on the acceleration pr...The interaction of high energy lepton jets composed of electrons and positrons with background electron–proton plasma is investigated numerically based upon particle-in-cell simulation,focusing on the acceleration processes of background protons due to the development of electromagnetic turbulence.Such interaction may be found in the universe when energetic lepton jets propagate in the interstellar media.When such a jet is injected into the background plasma,theWeibel instability is excited quickly,which leads to the development of plasma turbulence into the nonlinear stage.The turbulent electric and magnetic fields accelerate plasma particles via the Fermi II type acceleration,where the maximum energy of both electrons and protons can be accelerated to much higher than that of the incident jet particles.Because of background plasma acceleration,a collisionless electrostatic shock wave is formed,where some pre-accelerated protons are further accelerated when passing through the shock wave front.Dependence of proton acceleration on the beam-plasma density ratio and beam energy is investigated.For a given background plasma density,the maximum proton energy generally increases both with the density and kinetic energy of the injected jet.Moreover,for a homogeneous background plasma,the proton acceleration via both turbulent fields and collisionless shocks is found to be significant.In the case of an inhomogeneous plasma,the proton acceleration in the plasma turbulence is dominant.Our studies illustrate a scenario where protons from background plasma can be accelerated successively by the turbulent fields and collisionless shocks.展开更多
Extending the potential window of aqueous supercapacitors (SCs) up to 2.0 V is still a great challenge.Based on their good dynamic structural reversibility and open framework structure,the coordination superamolecular...Extending the potential window of aqueous supercapacitors (SCs) up to 2.0 V is still a great challenge.Based on their good dynamic structural reversibility and open framework structure,the coordination superamolecular networks (CSNs) exhibit rapid charge/discharge ability and excellent cycle stability.As a typical coordination superamolecular network (CSN),Prussian blue (denoted as CSN-PB),which self-assembled by the CN-ligand and iron ions is firstly in-situ grown on carbon cloth,followed by electro-deposition of MnO2 to form CSN-PB/MnO2 composite electrode.Benefiting from synergistic effect of the constituent components,as well as the open framework structure of CSN-PB,this composite electrode reaches a high potential window of 1.4 V (vs.Ag/AgCl) and delivers a good specific capacitance of 315.3 F·g^-1 in aqueous electrolyte.An aqueous asymmetric device,constructed with CSN-PB/MnO2 composite as cathode and activated carbon as anode,can work in a stable potential window of 2.4 V,exhibits a high energy density of 46.13 Wh·kg^-1 and excellent cycling stability with 85.5% capacitance retention after 20,000 cycles.This work provides a new concept of high dynamic structural reversibility from CSNs to increase the cell voltage of asymmetric SCs for further boosting energy density.展开更多
基金supported by the Science and Technology Department of Jiangxi Province(20212AEI91010)National Natural Science Foundation of China(31772067)+1 种基金Jiangxi Agriculture Research System(JXARS-14)Research Project of State Key Laboratory of Food Science and Technology(SKFL-ZZB-2)。
文摘Royal jelly(RJ)is rich in various nutrients with multiple health-promoting properties.This study aims to evaluate whether RJ can modulate related metabolite in the natural aging mice.Male C57BL/6J mice drank RJ solution daily for 9 months.Determination of serum lipids and pathological analysis exhibited that triglycerides,serum cholesterol,and low-density lipoprotein cholesterol were decreased by 31.15%,9.96%,and 22.58%,respectively,the morphology of brain nerve cells was also effectively recovered after RJ intervention.Lipidomic analysis showed that RJ could improve the levels of different kinds of lipids in aging mice brain,especially by increasing the content of antioxidant ether ester,and that the ratio of monounsaturated fatty acid to polyunsaturated fatty acid was up by 23.46%,which could alleviate oxidative stress.Moreover,the metabolism of glycerol phospholipids,glycerols,and fatty acids in aging mice could be regulated by RJ.RJ intervention can effectively improve lipid metabolism disorders caused by aging.
基金supported by the Applied Basic Research Programs of the Sichuan Provincial Science and Technology Department(Grant number:2021YJ0129)Research Program of Science and Technology Department of Sichuan Province(Grant number:2021YFS0217)the National Natural Science Foundation of China(81870782)。
文摘Resection of oral and maxillofacial tumors is often accompanied by the inferior alveolar nerve neurectomy,resulting in abnormal sensation in lower lip.It is generally believed that spontaneous sensory recovery in this nerve injury is difficult.However,during our follow-up,patients with inferior alveolar nerve sacrifice showed different degrees of lower lip sensory recovery.In this study,a prospective cohort study was conducted to demonstrate this phenomenon and analyze the factors influencing sensory recovery.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12135009,11991074,11975154,and 12005287).
文摘The interaction of high energy lepton jets composed of electrons and positrons with background electron–proton plasma is investigated numerically based upon particle-in-cell simulation,focusing on the acceleration processes of background protons due to the development of electromagnetic turbulence.Such interaction may be found in the universe when energetic lepton jets propagate in the interstellar media.When such a jet is injected into the background plasma,theWeibel instability is excited quickly,which leads to the development of plasma turbulence into the nonlinear stage.The turbulent electric and magnetic fields accelerate plasma particles via the Fermi II type acceleration,where the maximum energy of both electrons and protons can be accelerated to much higher than that of the incident jet particles.Because of background plasma acceleration,a collisionless electrostatic shock wave is formed,where some pre-accelerated protons are further accelerated when passing through the shock wave front.Dependence of proton acceleration on the beam-plasma density ratio and beam energy is investigated.For a given background plasma density,the maximum proton energy generally increases both with the density and kinetic energy of the injected jet.Moreover,for a homogeneous background plasma,the proton acceleration via both turbulent fields and collisionless shocks is found to be significant.In the case of an inhomogeneous plasma,the proton acceleration in the plasma turbulence is dominant.Our studies illustrate a scenario where protons from background plasma can be accelerated successively by the turbulent fields and collisionless shocks.
基金the National Natural Science Foundation of China (Nos.51472275,20973203 and 91022012)Guangdong Natural Science Foundation (No.2014A030313207)as well as Laboratory Open Fund Project of Sun Yat-sen University (No.201610310003).
文摘Extending the potential window of aqueous supercapacitors (SCs) up to 2.0 V is still a great challenge.Based on their good dynamic structural reversibility and open framework structure,the coordination superamolecular networks (CSNs) exhibit rapid charge/discharge ability and excellent cycle stability.As a typical coordination superamolecular network (CSN),Prussian blue (denoted as CSN-PB),which self-assembled by the CN-ligand and iron ions is firstly in-situ grown on carbon cloth,followed by electro-deposition of MnO2 to form CSN-PB/MnO2 composite electrode.Benefiting from synergistic effect of the constituent components,as well as the open framework structure of CSN-PB,this composite electrode reaches a high potential window of 1.4 V (vs.Ag/AgCl) and delivers a good specific capacitance of 315.3 F·g^-1 in aqueous electrolyte.An aqueous asymmetric device,constructed with CSN-PB/MnO2 composite as cathode and activated carbon as anode,can work in a stable potential window of 2.4 V,exhibits a high energy density of 46.13 Wh·kg^-1 and excellent cycling stability with 85.5% capacitance retention after 20,000 cycles.This work provides a new concept of high dynamic structural reversibility from CSNs to increase the cell voltage of asymmetric SCs for further boosting energy density.
