Electricity price is of the first consideration for all the participants in electric power market and its characteristics are related to both market mechanism and variation in the behaviors of market participants. It ...Electricity price is of the first consideration for all the participants in electric power market and its characteristics are related to both market mechanism and variation in the behaviors of market participants. It is necessary to build a real-time price forecasting model with adaptive capability; and because there are outliers in the price data, they should be detected and filtrated in training the forecasting model by regression method. In view of these points, mis paper presents an electricity price forecasting method based on accurate on-line support vector regression (AOSVR) and outlier detection. Numerical testing results show that the method is effective in forecasting the electricity prices in electric power market展开更多
The effect of homocysteine (Hcy) on the synthesis of adrenomedullin (ADM) was examined in vascular fibroblasts of rats to explore the possible activity of ADM in cardiovascular diseases. ADM from cultured vascular fib...The effect of homocysteine (Hcy) on the synthesis of adrenomedullin (ADM) was examined in vascular fibroblasts of rats to explore the possible activity of ADM in cardiovascular diseases. ADM from cultured vascular fibroblasts was measured by Radioimmunoassay (RIA) and was characterized by reverse phase high performance liquid chromatography. ADM mRNA in the fibroblasts was quantitated by competitive RT-PCR. The synthesis of ADM from vascular fibroblasts was increased by Hcy in a concentration dependent manner. ADM content in cultured medium increased by 68%—150% (P < 0.01, as compared to the control) when the fibroblasts were incubated in 50—200 mmol·L-1 Hcy for 12 h, and the content increased by 55%—98% (P < 0.01) if the incubation lasted for 24 h. Hydrogen peroxide treatment also increased the synthesis of ADM and it promoted ADM synthesis synergetically with Hcy. The changes of ADM content were partially or completely inhibited by the antioxidant N-acetylcysteine (NAC) treatment. Hcy induced the increase of ADM mRNA and the amount of ADM mRNA was increased by 78% as compared with control (P < 0.05). NAC almost completely inhibited the increase of ADM mRNA induced by Hcy. In conclusion, Hcy treatment up-regulated the expression of ADM gene and increased the synthesis of ADM in vascular fibroblasts. Oxidative stress may be involved in the processes of the ADM changes induce by Hcy.展开更多
基金This paper is about a project financed by the National Outstanding Young Investigator Grant (6970025)863 High Tech Development Plan of China (2001AA413910) the Project of National Natural Science Foundation (60274054) the Key Project of National Natural Science Foundation (59937150)it is also supported by its cooperating project financed by 863 High Tech Development Plan of China (2004AA412050).
文摘Electricity price is of the first consideration for all the participants in electric power market and its characteristics are related to both market mechanism and variation in the behaviors of market participants. It is necessary to build a real-time price forecasting model with adaptive capability; and because there are outliers in the price data, they should be detected and filtrated in training the forecasting model by regression method. In view of these points, mis paper presents an electricity price forecasting method based on accurate on-line support vector regression (AOSVR) and outlier detection. Numerical testing results show that the method is effective in forecasting the electricity prices in electric power market
基金supported by the State Major Basic Research and Development Program(Grant No.G2000056905)the“985”Projects of Peking University.
文摘The effect of homocysteine (Hcy) on the synthesis of adrenomedullin (ADM) was examined in vascular fibroblasts of rats to explore the possible activity of ADM in cardiovascular diseases. ADM from cultured vascular fibroblasts was measured by Radioimmunoassay (RIA) and was characterized by reverse phase high performance liquid chromatography. ADM mRNA in the fibroblasts was quantitated by competitive RT-PCR. The synthesis of ADM from vascular fibroblasts was increased by Hcy in a concentration dependent manner. ADM content in cultured medium increased by 68%—150% (P < 0.01, as compared to the control) when the fibroblasts were incubated in 50—200 mmol·L-1 Hcy for 12 h, and the content increased by 55%—98% (P < 0.01) if the incubation lasted for 24 h. Hydrogen peroxide treatment also increased the synthesis of ADM and it promoted ADM synthesis synergetically with Hcy. The changes of ADM content were partially or completely inhibited by the antioxidant N-acetylcysteine (NAC) treatment. Hcy induced the increase of ADM mRNA and the amount of ADM mRNA was increased by 78% as compared with control (P < 0.05). NAC almost completely inhibited the increase of ADM mRNA induced by Hcy. In conclusion, Hcy treatment up-regulated the expression of ADM gene and increased the synthesis of ADM in vascular fibroblasts. Oxidative stress may be involved in the processes of the ADM changes induce by Hcy.
