The spread of severe acute respiratory syndrome coronavirus 2 worldwide has created a major threat to human life and safety.Antiviral drugs and antibiotics have poor therapeutic effects,and there is no specific treatm...The spread of severe acute respiratory syndrome coronavirus 2 worldwide has created a major threat to human life and safety.Antiviral drugs and antibiotics have poor therapeutic effects,and there is no specific treatment for this virus.Chest computed tomography(CT)plays an important role in the diagnosis and management of coronavirus disease 2019(COVID-19).We report a patient who was critically ill with COVID-19 and recovered after receiving transfusions of convalescent plasma.To evaluate the efficacy of convalescent plasma in the treatment of COVID-19,we compared chest CT findings,clinical manifestations,and laboratory findings before and after treatment with convalescent plasma.After the transfusion of convalescent plasma,clinical manifestations and indicators of inflammation improved,accompanied by an increase in the partial pressure of oxygen and oxygen saturation.Chest CT showed some resolution of the lung lesions,and multiple viral nucleic acid tests were negative.Therefore,the patient’s condition was improved after the transfusion of convalescent plasma,suggesting that it may be an effective treatment for patients who are critically ill with COVID-19.展开更多
Liver injury is found in some patients with coronavirus disease‑2019(COVID‑19).Both the clinical treatment efficacy and the patient’s prognosis are affected by the severity of liver injury.In addition,in some cases,l...Liver injury is found in some patients with coronavirus disease‑2019(COVID‑19).Both the clinical treatment efficacy and the patient’s prognosis are affected by the severity of liver injury.In addition,in some cases,liver injury may occur in the absence of respiratory symptoms.To date,liver injury diagnosed based on laboratory findings and abdominal computed tomography(CT)has been reported in COVID‑19 patients.The aim of this review was to summarize the mechanism of liver injury caused by COVID‑19 and describe the CT features of COVID‑19‑induced liver damage.展开更多
文摘The spread of severe acute respiratory syndrome coronavirus 2 worldwide has created a major threat to human life and safety.Antiviral drugs and antibiotics have poor therapeutic effects,and there is no specific treatment for this virus.Chest computed tomography(CT)plays an important role in the diagnosis and management of coronavirus disease 2019(COVID-19).We report a patient who was critically ill with COVID-19 and recovered after receiving transfusions of convalescent plasma.To evaluate the efficacy of convalescent plasma in the treatment of COVID-19,we compared chest CT findings,clinical manifestations,and laboratory findings before and after treatment with convalescent plasma.After the transfusion of convalescent plasma,clinical manifestations and indicators of inflammation improved,accompanied by an increase in the partial pressure of oxygen and oxygen saturation.Chest CT showed some resolution of the lung lesions,and multiple viral nucleic acid tests were negative.Therefore,the patient’s condition was improved after the transfusion of convalescent plasma,suggesting that it may be an effective treatment for patients who are critically ill with COVID-19.
基金supported by the Nanchong City Level Science and Technology Plan Project for the Novel Coronavirus Epidemic Prevention and Control Category(Grant No.20YFZJ0103)the Key Project of National Natural Science Foundation of China(Grant No.61936013)the National Natural Science Foundation of China(Grant No.81801674)for the conduct of this study.
文摘Liver injury is found in some patients with coronavirus disease‑2019(COVID‑19).Both the clinical treatment efficacy and the patient’s prognosis are affected by the severity of liver injury.In addition,in some cases,liver injury may occur in the absence of respiratory symptoms.To date,liver injury diagnosed based on laboratory findings and abdominal computed tomography(CT)has been reported in COVID‑19 patients.The aim of this review was to summarize the mechanism of liver injury caused by COVID‑19 and describe the CT features of COVID‑19‑induced liver damage.
