Dear Editor,Circulating tumor cells(CTCs)are instrumental in hematogenous metastasis and are widely studied using liquid biopsy methods.These involve analysis and characterization of CTCs from fractionally small blood...Dear Editor,Circulating tumor cells(CTCs)are instrumental in hematogenous metastasis and are widely studied using liquid biopsy methods.These involve analysis and characterization of CTCs from fractionally small blood samples drawn from patients1.Liquid biopsy implicitly assumes that the number and phenotypical distribution of CTCs in small blood samples is representative of the full peripheral blood volume,and furthermore that CTC numbers are approximately constant over the days and hours surrounding the blood draw.展开更多
文摘Dear Editor,Circulating tumor cells(CTCs)are instrumental in hematogenous metastasis and are widely studied using liquid biopsy methods.These involve analysis and characterization of CTCs from fractionally small blood samples drawn from patients1.Liquid biopsy implicitly assumes that the number and phenotypical distribution of CTCs in small blood samples is representative of the full peripheral blood volume,and furthermore that CTC numbers are approximately constant over the days and hours surrounding the blood draw.
