Objective: To comprehensively understand the infection status of human T-lymphotropic virus (HTLV) among the voluntary blood donors in Yulin City and accurately assess the impact of HTLV on the current situation of bl...Objective: To comprehensively understand the infection status of human T-lymphotropic virus (HTLV) among the voluntary blood donors in Yulin City and accurately assess the impact of HTLV on the current situation of blood safety in Yulin City. Methods: A total of 113,588 blood samples from voluntary blood donors collected in Yulin City from January 2023 to June 2024 were selected. The HTLV-I/II antibody screening was carried out on these samples using the HTLV enzyme-linked immunosorbent assay (ELISA) kit. For the samples with reactive screening results, further confirmation was performed by means of immunoblotting assay and real-time fluorescent quantitative polymerase chain reaction (qPCR). Results: Among the 113,588 blood samples from voluntary blood donors, 20 samples showed positive reactions for HTLV-I/II antibodies, with an initial screening positive reaction rate of 1.76‱. After confirmation, 8 of them were confirmed to be HTLV-I positive, with a positive rate of 0.7‱, and no HTLV-II positive blood donors were detected. Moreover, all the HTLV-I positive blood donors were Han people from Yulin. In addition, by following up the 4 children of a female positive blood donor, it was found that her eldest daughter was confirmed to be HTLV-I positive, while the test results of the other children were negative. Conclusion: At present, there is no HTLV-II infection among the voluntary blood donors in Yulin City. There is a relatively low level of HTLV-I infection mainly among the local people. Continuous monitoring is still needed in the future. Emphasis should be placed on strengthening the publicity, education and testing work for the close relatives of the confirmed positive blood donors and women during pregnancy and childbirth periods, so as to prevent and reduce the HTLV infection caused by family transmission.展开更多
Ferredoxins(Fds)in plastids are the most upstream stromal electron receptors shuttling electrons to downstream metabolic systems and function in various physiological processes of dicots,but their roles in monocots’r...Ferredoxins(Fds)in plastids are the most upstream stromal electron receptors shuttling electrons to downstream metabolic systems and function in various physiological processes of dicots,but their roles in monocots’response to stresses are still unclear.In this study,the functions of OsFd4,the major non-photosynthetic type Fd in rice,were characterized under oxidative stress and Xanthomonas oryzae pv.oryzae(Xoo)infection.OsFd4-knockout mutants displayed no defects in key agronomic traits and blast resistance,but were more sensitive to hydrogen peroxide(H2O2)treatment than the wild type.Transient expression of OsFd4 alleviated H2O2-induced rice cell death,suggesting that OsFd4 contributes to rice tolerance to exogenous oxidative stress.Deletion of OsFd4 enhanced rice immune responses against Xoo.OsFd4 formed a complex in vivo with itself and OsFd1,the major photosynthetic Fd in rice,and OsFd1 transcripts were increased in leaf and root tissues of the OsFd4-knockout mutants.These results indicate that OsFd4 is involved in regulating rice defense against stresses and interplays with OsFd1.展开更多
The packet classification is a fundamental process in provisioning security and quality of service for many intelligent network-embedded systems running in the Internet of Things(IoT).In recent years,researchers have ...The packet classification is a fundamental process in provisioning security and quality of service for many intelligent network-embedded systems running in the Internet of Things(IoT).In recent years,researchers have tried to develop hardware-based solutions for the classification of Internet packets.Due to higher throughput and shorter delays,these solutions are considered as a major key to improving the quality of services.Most of these efforts have attempted to implement a software algorithm on the FPGA to reduce the processing time and enhance the throughput.The proposed architectures,however,cannot reach a compromise among power consumption,memory usage,and throughput rate.In view of this,the architecture proposed in this paper contains a pipelinebased micro-core that is used in network processors to classify packets.To this end,three architectures have been implemented using the proposed micro-core.The first architecture performs parallel classification based on header fields.The second one classifies packets in a serial manner.The last architecture is the pipeline-based classifier,which can increase performance by nine times.The proposed architectures have been implemented on an FPGA chip.The results are indicative of a reduction in memory usage as well as an increase in speedup and throughput.The architecture has a power consumption of is 1.294w,and its throughput with a frequency of 233 MHz exceeds 147 Gbps.展开更多
文摘Objective: To comprehensively understand the infection status of human T-lymphotropic virus (HTLV) among the voluntary blood donors in Yulin City and accurately assess the impact of HTLV on the current situation of blood safety in Yulin City. Methods: A total of 113,588 blood samples from voluntary blood donors collected in Yulin City from January 2023 to June 2024 were selected. The HTLV-I/II antibody screening was carried out on these samples using the HTLV enzyme-linked immunosorbent assay (ELISA) kit. For the samples with reactive screening results, further confirmation was performed by means of immunoblotting assay and real-time fluorescent quantitative polymerase chain reaction (qPCR). Results: Among the 113,588 blood samples from voluntary blood donors, 20 samples showed positive reactions for HTLV-I/II antibodies, with an initial screening positive reaction rate of 1.76‱. After confirmation, 8 of them were confirmed to be HTLV-I positive, with a positive rate of 0.7‱, and no HTLV-II positive blood donors were detected. Moreover, all the HTLV-I positive blood donors were Han people from Yulin. In addition, by following up the 4 children of a female positive blood donor, it was found that her eldest daughter was confirmed to be HTLV-I positive, while the test results of the other children were negative. Conclusion: At present, there is no HTLV-II infection among the voluntary blood donors in Yulin City. There is a relatively low level of HTLV-I infection mainly among the local people. Continuous monitoring is still needed in the future. Emphasis should be placed on strengthening the publicity, education and testing work for the close relatives of the confirmed positive blood donors and women during pregnancy and childbirth periods, so as to prevent and reduce the HTLV infection caused by family transmission.
基金the National Natural Science Foundation of China(31701777)the National Natural Science Foundation for International Exchanges(NSFC-RS)(31911530181)+1 种基金the Fujian Provincial Science and Technology Key Project(2022NZ030014)Key Plant Protection Disciplinary Development Project(Fujian Agriculture and Forestry University,103-722022001)to Mo Wang.
文摘Ferredoxins(Fds)in plastids are the most upstream stromal electron receptors shuttling electrons to downstream metabolic systems and function in various physiological processes of dicots,but their roles in monocots’response to stresses are still unclear.In this study,the functions of OsFd4,the major non-photosynthetic type Fd in rice,were characterized under oxidative stress and Xanthomonas oryzae pv.oryzae(Xoo)infection.OsFd4-knockout mutants displayed no defects in key agronomic traits and blast resistance,but were more sensitive to hydrogen peroxide(H2O2)treatment than the wild type.Transient expression of OsFd4 alleviated H2O2-induced rice cell death,suggesting that OsFd4 contributes to rice tolerance to exogenous oxidative stress.Deletion of OsFd4 enhanced rice immune responses against Xoo.OsFd4 formed a complex in vivo with itself and OsFd1,the major photosynthetic Fd in rice,and OsFd1 transcripts were increased in leaf and root tissues of the OsFd4-knockout mutants.These results indicate that OsFd4 is involved in regulating rice defense against stresses and interplays with OsFd1.
文摘The packet classification is a fundamental process in provisioning security and quality of service for many intelligent network-embedded systems running in the Internet of Things(IoT).In recent years,researchers have tried to develop hardware-based solutions for the classification of Internet packets.Due to higher throughput and shorter delays,these solutions are considered as a major key to improving the quality of services.Most of these efforts have attempted to implement a software algorithm on the FPGA to reduce the processing time and enhance the throughput.The proposed architectures,however,cannot reach a compromise among power consumption,memory usage,and throughput rate.In view of this,the architecture proposed in this paper contains a pipelinebased micro-core that is used in network processors to classify packets.To this end,three architectures have been implemented using the proposed micro-core.The first architecture performs parallel classification based on header fields.The second one classifies packets in a serial manner.The last architecture is the pipeline-based classifier,which can increase performance by nine times.The proposed architectures have been implemented on an FPGA chip.The results are indicative of a reduction in memory usage as well as an increase in speedup and throughput.The architecture has a power consumption of is 1.294w,and its throughput with a frequency of 233 MHz exceeds 147 Gbps.
