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Daily consumption of Siraitia grosvenorii alleviated lipid accumulation and colon barrier injury via modulation of gut microbiota in high fat and high sugar diet C57BL/6 mice
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作者 Jingru Song Yulu Wei +4 位作者 Xiaohua Jiang Hongwei Liu Xiaojie Yan Dianpeng Li fenglai lu 《Food Science and Human Wellness》 2025年第10期4035-4046,共12页
Siraitia grosvenorii(SG),a traditional edible medicine in China,has shown potential application in health foods due to multiple bioactivities.However,few comparative studies have investigated the effect of daily intak... Siraitia grosvenorii(SG),a traditional edible medicine in China,has shown potential application in health foods due to multiple bioactivities.However,few comparative studies have investigated the effect of daily intake of SG products by traditional drinking way on alleviating metabolic disorders caused by long-term high fat and high sugar diet(HF-HSD).This study investigated the effects of 2 commercial SG products(SG juice containing comprehensive compositions and mogrosides extract containing high content of mogroside V)supplement on fat content,lipid accumulation,colon barrier and gut microbiota in a 38-week HF-HSD mice trial.Results showed that the SG intervention could decrease the weight gain and body fat content,alleviated lipid accumulation,low-grade inflammation and colon barrier injury.SG juice intake was found to increase the antioxidant enzyme activities of serum glutathione peroxidase and liver superoxide dismutase.16S r RNA analysis found that SG could restore the gut microbiota with downregulation of harmful bacteria increased by HF-HSD and enhancement of the abundances of beneficial genus.In particular,SG juice significantly enriched taxonomic family Prevotellaceae and genus Alloprevotella.These results indicated that SG might be a functional additive to prevent disease risk caused by excess fat and sugar diet,and active ingredients resulting to the discrepancy of performance especially on gut microbiota are worthy of in-depth investigation. 展开更多
关键词 Siraitia grosvenorii Mogrosides Lipid accumulation Colon barrier INFLAMMATION Gut microbiota
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Soil microorganisms alleviate the allelopathic effect of Eucalyptus grandis × E. urophylla leachates on Brassica chinensis 被引量:7
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作者 fenglai lu Lilang Zheng +3 位作者 Yueyuan Chen Dianpeng Li Rensen Zeng Huashou Li 《Journal of Forestry Research》 SCIE CAS CSCD 2017年第6期1198-1202,共5页
Soil microbes may be critical players in determining the allelopathic potential of some plants. Low levels of plant community biodiversity in Eucalyptus plantations have been attributed to the allelopathic potential o... Soil microbes may be critical players in determining the allelopathic potential of some plants. Low levels of plant community biodiversity in Eucalyptus plantations have been attributed to the allelopathic potential of these tree species. The role of soil microbes in the allelopathic effect of leaf leachates of the hybrid tree Eucalyptus grandis x E. urophylla, was tested in Petri dish assays with Brassica chinensis as a receiver plant. Soils were collected from either a local garden (soil A) or a Eucalyptus plantation (soil B) and half of each soil was sterilized to remove microbes. These soils were then treated with E. grandis x E. urophylla leachates for 0-72 h. Seed germination of B. chinensis was significantly inhibited in soils treated with leaf leachates relative to untreated soils. The inhibitory effect of the leaf leachates was more pronounced in sterilized soils. Total phenolic content was obvious lower in nonsterile leachate-treated soils than in sterile soils. Biomass of B. chinensis was negatively correlated with the total phenolic content in soils. Our findings suggest that soil microbes can alleviate the allelopathic potential of Eucalyptus and thereby its negative impact on plant growth. 展开更多
关键词 ALLELOPATHY Eucalyptus grandis x E. urophylla Leaf leachate Soil microbes
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Research Progress of Triterpenoid Secondary Metabolites in Cucurbitaceae Plants
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作者 Zhiyi HU Lichun ZHAO +1 位作者 fenglai lu Dianpeng LI 《Agricultural Biotechnology》 CAS 2019年第1期34-39,42,共7页
In this paper,the advances in study on triterpenoids in Trichosanthes,Hemsleya,Gynostemma,Actinostemma and Siraitia Merr. plants were reviewed.Terpenoids are the main secondary metabolites of Cucurbitaceae and have ob... In this paper,the advances in study on triterpenoids in Trichosanthes,Hemsleya,Gynostemma,Actinostemma and Siraitia Merr. plants were reviewed.Terpenoids are the main secondary metabolites of Cucurbitaceae and have obvious pharmacological activity. It is noteworthy that in these plants,there are a variety of triterpenoids,which are diverse in structure. Triterpenoid saponins have greater potential for development. 展开更多
关键词 Cucurbitacea TRITERPENOIDS SECONDARY METABOLITES Trichosanthes Hemsleya GYNOSTEMMA Actinostemma Siraitia Merr
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