An efficient method for the preparation of indolin-3-one derivatives from 2-alkynylnitrobenzenes and indoles under alkaline conditions is described.In this reaction,the Wittig process is initiated by PPh_(3),and then ...An efficient method for the preparation of indolin-3-one derivatives from 2-alkynylnitrobenzenes and indoles under alkaline conditions is described.In this reaction,the Wittig process is initiated by PPh_(3),and then the indole is activated under the action of the base to offer the indolin-3-one substituted by C(2)-indole in up to 98%yield.A variety of functionalized indolin-3-one derivatives were synthesized by modification of 2-alkynylnitroarenes under transition-metal free conditions.展开更多
文摘An efficient method for the preparation of indolin-3-one derivatives from 2-alkynylnitrobenzenes and indoles under alkaline conditions is described.In this reaction,the Wittig process is initiated by PPh_(3),and then the indole is activated under the action of the base to offer the indolin-3-one substituted by C(2)-indole in up to 98%yield.A variety of functionalized indolin-3-one derivatives were synthesized by modification of 2-alkynylnitroarenes under transition-metal free conditions.
