目的:分析睑板腺功能障碍型干眼(MGD)和水液缺乏型干眼(ADDE)患者的像差和散射相关参数,评估两种干眼类型患者的视觉质量。方法:将2018-01/10在我院门诊就诊的MGD患者25例(MGD组),ADDE患者25例(ADDE组),同时期就诊的健康人25例(对照组)...目的:分析睑板腺功能障碍型干眼(MGD)和水液缺乏型干眼(ADDE)患者的像差和散射相关参数,评估两种干眼类型患者的视觉质量。方法:将2018-01/10在我院门诊就诊的MGD患者25例(MGD组),ADDE患者25例(ADDE组),同时期就诊的健康人25例(对照组)纳入此次研究。三组受试对象填写眼表疾病指数量表(OSDI),接受泪液相关检查:泪液分泌试验(SⅠt)、泪膜破裂时间(TBUT)、角膜荧光染色(FL)。使用iTrace分析仪记录三组受试对象的高阶像差(HO)、球差(SA)、彗差(CA)和三叶草差(TA)的均方根值(RMS)。利用双通道视觉分析仪(OQASⅡ)记录三组受试对象自然状态下的散射值,包括调制传递函数截止频率(MTF cutoff)、斯特列尔比(SR)、客观散射指数(OSI),以及持续睁眼状态下OSI动态变化值(OSI均值)。结果:MGD组的OSDI评分明显高于ADDE组(38.2±5.6 vs 32.2±7.2分,P<0.01)。ADDE组的SⅠt明显低于MGD组(1.98±0.92 vs 12.52±6.80mm/5min,P<0.001)。MGD组的TBUT和FL显著低于ADDE组(TBUT:3.27±1.91 vs 6.02±1.05s,FL:3.27±2.18 vs 6.23±2.19,均P<0.001)。MGD组和ADDE组的HO、CA、TA、SA的RMS值均显著高于对照组(均P<0.001)。MGD组和ADDE组的HO、CA、TA、SA均无显著性差异(HO:0.385±0.081 vs 0.344±0.092,CA:0.210±0.062 vs 0.175±0.075,TA:0.107±0.056 vs 0.086±0.042,SA:0.322±0.078 vs 0.273±0.097,HO:t=1.67,P>0.05;CA:t=1.80,P>0.05;TA:t=1.50,P>0.05;SA:t=1.97,P>0.05)。MGD和ADDE组之间的MTF cutoff、SR、OSI无差异(MTF cutoff:33.28±8.28 vs 37.12±9.53,SR:0.19±0.06 vs 0.22±0.08,OSI:1.30±0.32 vs 1.12±0.52,MTF cutoff:t=1.52,P>0.05;SR:t=1.50,P>0.05;OSI:t=1.47,P>0.05)。持续睁眼状态下MGD组的OSI均值明显高于ADDE组(2.386±0.118 vs 1.554±0.058,P<0.001)。结论:治疗干眼的同时需要关注改善患者的视觉质量,MGD患者的视觉质量影响比ADDE患者更加严重。泪膜动态状态下的OSI均值是评估干眼患者视觉质量的敏感指标。展开更多
The femtosecond laser is a type of laser that can produce pulses of light of extremely short duration.The application of femtosecond laser in surgery results in no thermal effect or shock wave,so that this laser is un...The femtosecond laser is a type of laser that can produce pulses of light of extremely short duration.The application of femtosecond laser in surgery results in no thermal effect or shock wave,so that this laser is unlikely to cause tissue injuries outside the irradiation area of the laser beam. The femtosecond laser shows promising applications in refractive surgery and corneal transplantation due to its high precision and predictability. In this paper, we review the clinical application of the femtosecond laser in refractive surgery and corneal transplantation.展开更多
Environmentally friendly antiferroelectric NaNbO,(NN)materials exhibit promising potential in energy storage and electrostrain applications.At room temperature,NN is an antiferroelectric P phase(Space group Pbma)that ...Environmentally friendly antiferroelectric NaNbO,(NN)materials exhibit promising potential in energy storage and electrostrain applications.At room temperature,NN is an antiferroelectric P phase(Space group Pbma)that coexists with a metastable ferroelectric Q phase(Space group P2_(1)ma),so the electric fieldinduced phase transition is irreversible.To stabilize the intrinsic antiferroelectric properties of NNs,phase structure regulation has emerged as a critical research focus.We chose the variable-valence elements Sn and Ce for doping in NN.Through atmospheric sintering,the valence states of the doped ions were altered,resulting in changes in their corresponding substitution positions.This confirmed that the doped ions could be successfully incorporated into the lattice as designed.Importantly,the x=0.04 ceramic exhibited a reversible phase transition between the AFE and FE state resulting in a standard double hysteresis loop at room temperature and a large electrostrain of 0.38%.These findings demonstrat that valence state-controlled co-doping effectively optimizes the antiferroelectric phase stability and functional performance of NN basedmaterials.展开更多
文摘目的:分析睑板腺功能障碍型干眼(MGD)和水液缺乏型干眼(ADDE)患者的像差和散射相关参数,评估两种干眼类型患者的视觉质量。方法:将2018-01/10在我院门诊就诊的MGD患者25例(MGD组),ADDE患者25例(ADDE组),同时期就诊的健康人25例(对照组)纳入此次研究。三组受试对象填写眼表疾病指数量表(OSDI),接受泪液相关检查:泪液分泌试验(SⅠt)、泪膜破裂时间(TBUT)、角膜荧光染色(FL)。使用iTrace分析仪记录三组受试对象的高阶像差(HO)、球差(SA)、彗差(CA)和三叶草差(TA)的均方根值(RMS)。利用双通道视觉分析仪(OQASⅡ)记录三组受试对象自然状态下的散射值,包括调制传递函数截止频率(MTF cutoff)、斯特列尔比(SR)、客观散射指数(OSI),以及持续睁眼状态下OSI动态变化值(OSI均值)。结果:MGD组的OSDI评分明显高于ADDE组(38.2±5.6 vs 32.2±7.2分,P<0.01)。ADDE组的SⅠt明显低于MGD组(1.98±0.92 vs 12.52±6.80mm/5min,P<0.001)。MGD组的TBUT和FL显著低于ADDE组(TBUT:3.27±1.91 vs 6.02±1.05s,FL:3.27±2.18 vs 6.23±2.19,均P<0.001)。MGD组和ADDE组的HO、CA、TA、SA的RMS值均显著高于对照组(均P<0.001)。MGD组和ADDE组的HO、CA、TA、SA均无显著性差异(HO:0.385±0.081 vs 0.344±0.092,CA:0.210±0.062 vs 0.175±0.075,TA:0.107±0.056 vs 0.086±0.042,SA:0.322±0.078 vs 0.273±0.097,HO:t=1.67,P>0.05;CA:t=1.80,P>0.05;TA:t=1.50,P>0.05;SA:t=1.97,P>0.05)。MGD和ADDE组之间的MTF cutoff、SR、OSI无差异(MTF cutoff:33.28±8.28 vs 37.12±9.53,SR:0.19±0.06 vs 0.22±0.08,OSI:1.30±0.32 vs 1.12±0.52,MTF cutoff:t=1.52,P>0.05;SR:t=1.50,P>0.05;OSI:t=1.47,P>0.05)。持续睁眼状态下MGD组的OSI均值明显高于ADDE组(2.386±0.118 vs 1.554±0.058,P<0.001)。结论:治疗干眼的同时需要关注改善患者的视觉质量,MGD患者的视觉质量影响比ADDE患者更加严重。泪膜动态状态下的OSI均值是评估干眼患者视觉质量的敏感指标。
文摘The femtosecond laser is a type of laser that can produce pulses of light of extremely short duration.The application of femtosecond laser in surgery results in no thermal effect or shock wave,so that this laser is unlikely to cause tissue injuries outside the irradiation area of the laser beam. The femtosecond laser shows promising applications in refractive surgery and corneal transplantation due to its high precision and predictability. In this paper, we review the clinical application of the femtosecond laser in refractive surgery and corneal transplantation.
基金sponsored by the Guizhou Tongren University Ph.D.Start-up Fund,China(No.trxyDH2313)Department of Education of Guizhou Province,China(No.QJ[2022]055)+1 种基金Guizhou Key Laboratory of Green Metallurgy and Process Strengthening(No.[2023]026)Jingdezhen University Ph.D.Startup Fund,China(No.jdzxy2502).
文摘Environmentally friendly antiferroelectric NaNbO,(NN)materials exhibit promising potential in energy storage and electrostrain applications.At room temperature,NN is an antiferroelectric P phase(Space group Pbma)that coexists with a metastable ferroelectric Q phase(Space group P2_(1)ma),so the electric fieldinduced phase transition is irreversible.To stabilize the intrinsic antiferroelectric properties of NNs,phase structure regulation has emerged as a critical research focus.We chose the variable-valence elements Sn and Ce for doping in NN.Through atmospheric sintering,the valence states of the doped ions were altered,resulting in changes in their corresponding substitution positions.This confirmed that the doped ions could be successfully incorporated into the lattice as designed.Importantly,the x=0.04 ceramic exhibited a reversible phase transition between the AFE and FE state resulting in a standard double hysteresis loop at room temperature and a large electrostrain of 0.38%.These findings demonstrat that valence state-controlled co-doping effectively optimizes the antiferroelectric phase stability and functional performance of NN basedmaterials.
