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Preventing brain aging by the artificial enforcement of the unfolded protein response:future directions
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作者 felipe cabral-miranda Claudio Hetz 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期393-394,共2页
As the life expectancy of the world’s population increases,age-related diseases are emerging as one of the greatest problems facing modern society.The onset of dementia and neurodegenerative diseases is strictly depe... As the life expectancy of the world’s population increases,age-related diseases are emerging as one of the greatest problems facing modern society.The onset of dementia and neurodegenerative diseases is strictly dependent on aging as a major risk factor and has a profound impact on various aspects of the lives of individuals and their families. 展开更多
关键词 DISEASES AGING DIRECTIONS
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Hevin/sparcl-1 as a potential biomarker and therapy in age-associated cognitive decline
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作者 felipe cabral-miranda Flávia C.A.Gomes 《Neural Regeneration Research》 2026年第6期2357-2358,共2页
Astrocytes,a major class of glial cells,have emerged as crucial regulators of synaptic function,neuronal homeostasis,and cognitive processes(Cabral-Miranda et al.,2024).These star-shaped cells not only provide structu... Astrocytes,a major class of glial cells,have emerged as crucial regulators of synaptic function,neuronal homeostasis,and cognitive processes(Cabral-Miranda et al.,2024).These star-shaped cells not only provide structural and metabolic support to neurons but also actively participate in modulating synaptic transmission,neurovascular coupling,and inflammatory responses in the brain. 展开更多
关键词 synaptic function modulating synaptic transmissionneurovascular astrocytes neuronal homeostasis age associated cognitive decline glial cellshave hevin sparcl therapy
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