Orthopedic surgeries often require a long recovery period, but Hui medicine offers promising strategies for rapid rehabilitation. This paper explores the integration of Hui medicine into postoperative care, focusing o...Orthopedic surgeries often require a long recovery period, but Hui medicine offers promising strategies for rapid rehabilitation. This paper explores the integration of Hui medicine into postoperative care, focusing on herbal remedies, physical therapies, and dietary adjustments. It uses a variety of methods, such as pasting, Tazi, acupuncture, diet therapy, medicine therapy, etc., to provide comprehensive treatment for various bone diseases. In the field of Hui medicine, through in-depth research and clinical verification, more therapies and drugs with unique curative effects have been discovered. Orthopedic rehabilitation and fumigation therapy play an important role in the rehabilitation stage of the disease, helping patients recover limb function, reduce pain, and improve quality of life. This paper elaborates on the spread and influence of Islamic Arab medical civilization in China and introduces the outstanding achievements of Hui medicine department and Hui medicine as important branches of this medical system. Through the in-depth study of relevant literature and historical data, the brilliant achievements of Hui medicine in inheritance and innovation are further revealed. In addition, the article also discusses the combination of modern science, technology, and traditional medicine--which has injected new vitality into the development of traditional medicine. Hui medicine, with its unique theoretical system and therapeutic methods, offers promising approaches to enhance the recovery process. Rehabilitation, acupuncture and fumigation treatment are typical representatives of the Sinicization of Islamic Arab medical civilization, and have made important contributions to the development of traditional Chinese medicine. At the same time, the rich experience and unique therapy of Hui medicine provide useful reference and inspiration for modern medicine. This paper overviews the effectiveness of Hui medicine in promoting rapid rehabilitation after orthopedic surgery.展开更多
The Dunhuang Mogao Grottoes in China was designated as a world heritage site by UNESCO in 1987 and is famous for its cultural relics. Water is the most active factor that harms the relics in the caves as it damages th...The Dunhuang Mogao Grottoes in China was designated as a world heritage site by UNESCO in 1987 and is famous for its cultural relics. Water is the most active factor that harms the relics in the caves as it damages the grotto murals and painted sculptures. Thus, determining the water sources and driving forces of water movement is a key issue for protecting these cultural relics. These issues have troubled relics protectors for a long time. In this study, the authors chose a representative cave in the Mogao Grottoes and, by completely sealing the cave to make a closed system, measured the water vapor from the surrounding rock. This was accomplished by installing a condensation-dehumidification temperature-humidity control system for the collection of water vapor. The results show that there is continuous evaporation from the deep surrounding rock into the cave. The daily evaporation capacity is determined to be 1.02 g/（d·m2）. The water sources and driving forces of water movement were further analyzed according to the character of the water evaporation and by monitoring the temperature and humidity of the surrounding rock. It was found that the water vapor in the cave derives from phreatic water. Moreover, the yearly fluctuation of temperature in the surrounding rock and geothermal forces are the basic powers responsible for driving phreatic evaporation. Under the action of the yearly temperature fluctuations, decomposition and combination of bound water acts as a ＂pump＂ that drives phreatic water migration and evaporation. When the temperature rises, bound water decomposes and evaporates; and when it falls, the rock absorbs moisture. This causes the phreatic water to move from deep regions to shallow ones. Determining the source and dynamic foundation of the water provides a firm scientific basis for protecting the valuable cultural relics in the caves.展开更多
The large warping deformation at platform of turbine blade directly affects the forming precision. In the present research, equivalent warping deformation was firstly presented to describe the extent of deformation at...The large warping deformation at platform of turbine blade directly affects the forming precision. In the present research, equivalent warping deformation was firstly presented to describe the extent of deformation at platform. To optimize the process parameters during investment casting to minimize the warping deformation of the platform, based on simulation with Pro CAST, the single factor method, orthogonal test, neural network and genetic algorithm were subsequently used to analyze the influence of pouring temperature, shell mold preheating temperature, furnace temperature and withdrawal velocity on dimensional accuracy of the platform of superalloyDD6 turbine blade. The accuracy of investment casting simulation was verified by measurement of platform at blade casting. The simulation results with the optimal process parameters illustrate that the equivalent warping deformation was dramatically reduced by 21.8% from 0.232295 mm to 0.181698 mm.展开更多
Sweetpotato （Ipomoea batatas L. Lain.） ranks fifth among the most important food crops, after rice, wheat, maize and cas- sava, on a fresh-weight basis in developing countries （Scott and Maldonado, 1999）. Sweetpot...Sweetpotato （Ipomoea batatas L. Lain.） ranks fifth among the most important food crops, after rice, wheat, maize and cas- sava, on a fresh-weight basis in developing countries （Scott and Maldonado, 1999）. Sweetpotato cultivars have white, yellow, purple or orange flesh, but only orange-fleshed sweetpotato cultivars are the rich sources of β-carotene, which is the precursor of vitamin A （Failla et al., 2009）. Accordingly, the orange-fleshed sweetpotato is the main source of 6-carotene for the people in underdeveloped coun- tries in Africa and Southeast Asia. Unfortunately, theβ-caro- tene content in most sweetpotato cultivars is rather low and insufficient in meeting the normal demand of human physi- ology （Liao et al., 2008）. Hence, developing sweetpotato cultivars rich inβ-carotene will be most desirable in crop development.展开更多
FMS-like tyrosine kinase 3(FLT3)mutation is strongly associated with poor prognosis in acute myeloid leukemia(AML).Though many FLT3 inhibitors have been developed for clinical application with 34%-56%complete remissio...FMS-like tyrosine kinase 3(FLT3)mutation is strongly associated with poor prognosis in acute myeloid leukemia(AML).Though many FLT3 inhibitors have been developed for clinical application with 34%-56%complete remission rate,patients would develop resistance sooner or later after initial response to tyrosine kinase inhibitors(TKIs),such as gilteritinib.And increasing studies have shown that several resistance related mutations of FLT3 emerged during the AML progression.Thus,further investigation is warranted for these FLT3mu,AML patients to achieve a better treatment outcome.4-Hydroxyphenyl retinamide(4-HPR)has been investigated extensively in animal models and clinical trials as an anticancer/chemopreventive agent and is currently used for protection against cancer development/recurrence,with minimal side effects.In this study,we performed gene-set enrichment analysis and found that down-regulated genes induced by 4-HPR were associated with FLT3-ITD gene sets.CD34+ AML stem/progenitor cells separated from 32 AML samples were treated with 4-HPR.Correlation analysis showed that AML cells with FLT3-ITD genetic alteration were more sensitive to 4-HPR treatment than those without FLT3-ITD.Next,we treated 22 primary AML cells with 4-HPR and found that 4-HPR was more toxic to AML cells with FLT3-ITD.These results indicated that 4-HPR was preferentially cytotoxic to all FLT3-ITD AML cells irrespective of stem/progenitor cells or blast cells.4-HPR-induced reactive oxygen species(ROS)production and NF-kB inhibition might be the reason of 4-HPR selectivity on FLT3 mutated AML cells.展开更多
文摘Orthopedic surgeries often require a long recovery period, but Hui medicine offers promising strategies for rapid rehabilitation. This paper explores the integration of Hui medicine into postoperative care, focusing on herbal remedies, physical therapies, and dietary adjustments. It uses a variety of methods, such as pasting, Tazi, acupuncture, diet therapy, medicine therapy, etc., to provide comprehensive treatment for various bone diseases. In the field of Hui medicine, through in-depth research and clinical verification, more therapies and drugs with unique curative effects have been discovered. Orthopedic rehabilitation and fumigation therapy play an important role in the rehabilitation stage of the disease, helping patients recover limb function, reduce pain, and improve quality of life. This paper elaborates on the spread and influence of Islamic Arab medical civilization in China and introduces the outstanding achievements of Hui medicine department and Hui medicine as important branches of this medical system. Through the in-depth study of relevant literature and historical data, the brilliant achievements of Hui medicine in inheritance and innovation are further revealed. In addition, the article also discusses the combination of modern science, technology, and traditional medicine--which has injected new vitality into the development of traditional medicine. Hui medicine, with its unique theoretical system and therapeutic methods, offers promising approaches to enhance the recovery process. Rehabilitation, acupuncture and fumigation treatment are typical representatives of the Sinicization of Islamic Arab medical civilization, and have made important contributions to the development of traditional Chinese medicine. At the same time, the rich experience and unique therapy of Hui medicine provide useful reference and inspiration for modern medicine. This paper overviews the effectiveness of Hui medicine in promoting rapid rehabilitation after orthopedic surgery.
基金the National Natural Science Foundation of China (41363009)the Gansu Province Science and Technology Plan (1308RJZF290)a project of the Dunhuang Academy (201306)
文摘The Dunhuang Mogao Grottoes in China was designated as a world heritage site by UNESCO in 1987 and is famous for its cultural relics. Water is the most active factor that harms the relics in the caves as it damages the grotto murals and painted sculptures. Thus, determining the water sources and driving forces of water movement is a key issue for protecting these cultural relics. These issues have troubled relics protectors for a long time. In this study, the authors chose a representative cave in the Mogao Grottoes and, by completely sealing the cave to make a closed system, measured the water vapor from the surrounding rock. This was accomplished by installing a condensation-dehumidification temperature-humidity control system for the collection of water vapor. The results show that there is continuous evaporation from the deep surrounding rock into the cave. The daily evaporation capacity is determined to be 1.02 g/（d·m2）. The water sources and driving forces of water movement were further analyzed according to the character of the water evaporation and by monitoring the temperature and humidity of the surrounding rock. It was found that the water vapor in the cave derives from phreatic water. Moreover, the yearly fluctuation of temperature in the surrounding rock and geothermal forces are the basic powers responsible for driving phreatic evaporation. Under the action of the yearly temperature fluctuations, decomposition and combination of bound water acts as a ＂pump＂ that drives phreatic water migration and evaporation. When the temperature rises, bound water decomposes and evaporates; and when it falls, the rock absorbs moisture. This causes the phreatic water to move from deep regions to shallow ones. Determining the source and dynamic foundation of the water provides a firm scientific basis for protecting the valuable cultural relics in the caves.
基金financially supported by the National Natural Science Foundation of China(No.51371152)
文摘The large warping deformation at platform of turbine blade directly affects the forming precision. In the present research, equivalent warping deformation was firstly presented to describe the extent of deformation at platform. To optimize the process parameters during investment casting to minimize the warping deformation of the platform, based on simulation with Pro CAST, the single factor method, orthogonal test, neural network and genetic algorithm were subsequently used to analyze the influence of pouring temperature, shell mold preheating temperature, furnace temperature and withdrawal velocity on dimensional accuracy of the platform of superalloyDD6 turbine blade. The accuracy of investment casting simulation was verified by measurement of platform at blade casting. The simulation results with the optimal process parameters illustrate that the equivalent warping deformation was dramatically reduced by 21.8% from 0.232295 mm to 0.181698 mm.
基金supported by the National High-tech R&D Program(863 Program)(Nos.2011AA10A206 and 2012AA101204-3)Program for New Century Excellent Talents in University(No.NCET-12-0930)+1 种基金Fundamental Research Funds for the Central Universities(No.XDJK2013A024)the earmarked fund for China Agriculture Research System (No.CARS-11-C-20)
文摘Sweetpotato （Ipomoea batatas L. Lain.） ranks fifth among the most important food crops, after rice, wheat, maize and cas- sava, on a fresh-weight basis in developing countries （Scott and Maldonado, 1999）. Sweetpotato cultivars have white, yellow, purple or orange flesh, but only orange-fleshed sweetpotato cultivars are the rich sources of β-carotene, which is the precursor of vitamin A （Failla et al., 2009）. Accordingly, the orange-fleshed sweetpotato is the main source of 6-carotene for the people in underdeveloped coun- tries in Africa and Southeast Asia. Unfortunately, theβ-caro- tene content in most sweetpotato cultivars is rather low and insufficient in meeting the normal demand of human physi- ology （Liao et al., 2008）. Hence, developing sweetpotato cultivars rich inβ-carotene will be most desirable in crop development.
基金This work was partially funded by the National Natural Science Foundation of China(No.81300401)St.Baldrick’s Foundation International Scholar(No.581580)+1 种基金Natural Science Foundation of Guangdong Province(No.2015A030313460)Guangzhou Women and Children’s Medical Center(No.IP-2008-001 and No.GCP-2019-006).
文摘FMS-like tyrosine kinase 3(FLT3)mutation is strongly associated with poor prognosis in acute myeloid leukemia(AML).Though many FLT3 inhibitors have been developed for clinical application with 34%-56%complete remission rate,patients would develop resistance sooner or later after initial response to tyrosine kinase inhibitors(TKIs),such as gilteritinib.And increasing studies have shown that several resistance related mutations of FLT3 emerged during the AML progression.Thus,further investigation is warranted for these FLT3mu,AML patients to achieve a better treatment outcome.4-Hydroxyphenyl retinamide(4-HPR)has been investigated extensively in animal models and clinical trials as an anticancer/chemopreventive agent and is currently used for protection against cancer development/recurrence,with minimal side effects.In this study,we performed gene-set enrichment analysis and found that down-regulated genes induced by 4-HPR were associated with FLT3-ITD gene sets.CD34+ AML stem/progenitor cells separated from 32 AML samples were treated with 4-HPR.Correlation analysis showed that AML cells with FLT3-ITD genetic alteration were more sensitive to 4-HPR treatment than those without FLT3-ITD.Next,we treated 22 primary AML cells with 4-HPR and found that 4-HPR was more toxic to AML cells with FLT3-ITD.These results indicated that 4-HPR was preferentially cytotoxic to all FLT3-ITD AML cells irrespective of stem/progenitor cells or blast cells.4-HPR-induced reactive oxygen species(ROS)production and NF-kB inhibition might be the reason of 4-HPR selectivity on FLT3 mutated AML cells.
