Wheat germplasm is a fundamental resource for basic research,applied studies,and wheat breeding,which can be enriched normally by several paths,such as collecting natural lines,accumulating breeding lines,and introduc...Wheat germplasm is a fundamental resource for basic research,applied studies,and wheat breeding,which can be enriched normally by several paths,such as collecting natural lines,accumulating breeding lines,and introducing mutagenesis materials.Ethyl methane sulfonate(EMS)is an alkylating agent that can effectively introduce genetic variations in a wide variety of plant species.In this study,we created a million-scale EMS population(MEP)that started with the Chinese wheat cultivars‘Luyan 128’,‘Jimai 38’,‘Jimai 44’,and‘Shannong 30’.In the M1 generation,the MEP had numerous phenotypical variations,such as>3,000 chlorophyll-deficient mutants,2,519 compact spikes,and 1,692 male sterile spikes.There were also rare mutations,including 30 independent tillers each with double heads.Some M1 variations of chlorophyll-deficiency and compact spikes were inheritable,appearing in the M2 or M3 generations.To advance the entire MEP to higher generations,we adopted a single-seed descendent(SSD)approach.All other seed composites of M2 were used to screen other agronomically important traits,such as the tolerance to herbicide quizalofop-P-methyl.The MEP is available for collaborative projects,and provides a valuable toolbox for wheat genetics and breeding for sustainable agriculture.展开更多
Dear Editor,Mold-breaking progress in whole-genome sequencing and rapid accumulation of multi-omics data have revolutionized the research strategies of functional genomics in wheat(Wang et al.,2018).However,how to acc...Dear Editor,Mold-breaking progress in whole-genome sequencing and rapid accumulation of multi-omics data have revolutionized the research strategies of functional genomics in wheat(Wang et al.,2018).However,how to access these vast multi-omics data and to extract key information on genes of in-terest,is still challenging for most wet-lab or field wheat re-searchers who have little bioinformatic experiences and cannot access the expensive computational resources.Here,we pre-sent WheatOmics(http://wheatomics.sdau.edu.cn/,previously designated as Triticeae Multi-omics Center,http://202.194.139.32/),a free,web-accessible,and user-friendly platform.WheatOmics not only empowers the effective access to the visualized multi-omics data of user-interested genes but also offers several distinctive and practical toolkits that can ease almost every aspect of wheat functional genomics studies(Figure 1A).展开更多
Dear Editor,Crop pathogens cause substantial economic losses and reduce food security globally.Harnessing disease resistance genes and breeding resistant crops are the most effective ways to reduce losses caused by pa...Dear Editor,Crop pathogens cause substantial economic losses and reduce food security globally.Harnessing disease resistance genes and breeding resistant crops are the most effective ways to reduce losses caused by pathogens.Domestication and cultivar breeding of wheat and other crops have significantly reduced their genetic diversity.The reduced diversity has resulted in a shortage of disease resistance genes,which is a severe obstacle for wheat breeding.展开更多
With the continuous development of standardization and internationalization of traditional Chinese medicine(TCM),the necessity and importance of TCM international standard composition is becoming more and more promine...With the continuous development of standardization and internationalization of traditional Chinese medicine(TCM),the necessity and importance of TCM international standard composition is becoming more and more prominent.As the basis and premise of TCM internationalization,TCM international terminology standard is the key to bolster the international development of TCM and the dissemination of TCM culture.After thousands of years of development,TCM has formed a unique set of terms with rich content,which need to be standardized to facilitate modern international use.The author introduced 4 TCM international standardization organizations and analyzed the necessity of composing international standards of TCM terminology.Then,the author found several problems in the field and put forward corresponding suggestions based on the collection and comparative study of the existing TCM international terminology standards.This paper was written to provide a reference for TCM standardization learners,enthusiasts,and stakeholders by showcasing the current status and problems of TCM international terminology standards,spur the global spread of TCM,and broaden the influence of Chinese culture.展开更多
基金This work was supported by the National Key Research and Development Program of China(2022YFF1002300)the Quancheng‘5150’Talent Program,China(07962021047)the Agriculture Applied Technology Initiative of Jinan Government,China(CX202113).
文摘Wheat germplasm is a fundamental resource for basic research,applied studies,and wheat breeding,which can be enriched normally by several paths,such as collecting natural lines,accumulating breeding lines,and introducing mutagenesis materials.Ethyl methane sulfonate(EMS)is an alkylating agent that can effectively introduce genetic variations in a wide variety of plant species.In this study,we created a million-scale EMS population(MEP)that started with the Chinese wheat cultivars‘Luyan 128’,‘Jimai 38’,‘Jimai 44’,and‘Shannong 30’.In the M1 generation,the MEP had numerous phenotypical variations,such as>3,000 chlorophyll-deficient mutants,2,519 compact spikes,and 1,692 male sterile spikes.There were also rare mutations,including 30 independent tillers each with double heads.Some M1 variations of chlorophyll-deficiency and compact spikes were inheritable,appearing in the M2 or M3 generations.To advance the entire MEP to higher generations,we adopted a single-seed descendent(SSD)approach.All other seed composites of M2 were used to screen other agronomically important traits,such as the tolerance to herbicide quizalofop-P-methyl.The MEP is available for collaborative projects,and provides a valuable toolbox for wheat genetics and breeding for sustainable agriculture.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24020104)the National Natural Science Foundation of China(32072064,U1906202,31971935,and 31901494)the Natural Science Foundation of Jiangsu Province,China(BK20200110).
文摘Dear Editor,Mold-breaking progress in whole-genome sequencing and rapid accumulation of multi-omics data have revolutionized the research strategies of functional genomics in wheat(Wang et al.,2018).However,how to access these vast multi-omics data and to extract key information on genes of in-terest,is still challenging for most wet-lab or field wheat re-searchers who have little bioinformatic experiences and cannot access the expensive computational resources.Here,we pre-sent WheatOmics(http://wheatomics.sdau.edu.cn/,previously designated as Triticeae Multi-omics Center,http://202.194.139.32/),a free,web-accessible,and user-friendly platform.WheatOmics not only empowers the effective access to the visualized multi-omics data of user-interested genes but also offers several distinctive and practical toolkits that can ease almost every aspect of wheat functional genomics studies(Figure 1A).
基金supported by the Key R&D Program of Shandong Province,China(2024LZGC001,2023TZXD086)The public re-sequencing data of rye germplasm were obtained from the NCBI database(accession numbers PRJNA737291,PRJEB6215,and PRJEB34439)the National Genomics Data Center of China(accession number PRJCA006012)。
文摘Dear Editor,Crop pathogens cause substantial economic losses and reduce food security globally.Harnessing disease resistance genes and breeding resistant crops are the most effective ways to reduce losses caused by pathogens.Domestication and cultivar breeding of wheat and other crops have significantly reduced their genetic diversity.The reduced diversity has resulted in a shortage of disease resistance genes,which is a severe obstacle for wheat breeding.
基金Revision of the national standard of“Basic Theory Nomenclature of Traditional Chinese Medicine”by the National Standardization Administration Committee(20233759-T-468).
文摘With the continuous development of standardization and internationalization of traditional Chinese medicine(TCM),the necessity and importance of TCM international standard composition is becoming more and more prominent.As the basis and premise of TCM internationalization,TCM international terminology standard is the key to bolster the international development of TCM and the dissemination of TCM culture.After thousands of years of development,TCM has formed a unique set of terms with rich content,which need to be standardized to facilitate modern international use.The author introduced 4 TCM international standardization organizations and analyzed the necessity of composing international standards of TCM terminology.Then,the author found several problems in the field and put forward corresponding suggestions based on the collection and comparative study of the existing TCM international terminology standards.This paper was written to provide a reference for TCM standardization learners,enthusiasts,and stakeholders by showcasing the current status and problems of TCM international terminology standards,spur the global spread of TCM,and broaden the influence of Chinese culture.
