Mercury pollution,in conjunction with other contaminants,hampers progress toward the United Nations Sustainable Development Goals.The Minamata Convention on Mercury,which came into force in 2017,represents a critical ...Mercury pollution,in conjunction with other contaminants,hampers progress toward the United Nations Sustainable Development Goals.The Minamata Convention on Mercury,which came into force in 2017,represents a critical step in combating this global issue.However,evaluating its effectiveness faces a major challenge,that is,establishing a clear link between reduced mercury emissions and lessened human exposure to neurotoxic methylmercury.Here,we propose that a previously overlooked methylmercury detoxification pathway in primary producers holds the potential to bridge the gaps in the emission-exposure nexus.A comprehensive understanding of this in vivo methylmercury demethylation and mercury reduction will enhance the effectiveness of global mercury mitigation efforts,accelerating our pace toward a sustainable future.展开更多
There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health....There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health.As a result,the hazards and risks of nanoplastics remain uncertain.Here,we identify key knowledge gaps by evaluating the exposure of nanoplastics in the environment,assessing their bio-nano interactions,and examining their potential risks to humans and the environment.We suggest considering nanoplastics a complex and dynamic mixture of polymers,additives,and contaminants,with interconnected risks to environmental and human health.We call for comprehensive integration of One Health approach to produce robust multidisciplinary evidence to nanoplastics threats at the planetary level.Although there are many challenges,this holistic approach incorporates the relevance of environmental exposure and multi-sectoral responses,which provide the opportunity to identify the risk mitigation strategies of nanoplastics to build resilient health systems.展开更多
基金supported by the National Natural Science Foundation of China(42222702,42525710)the Natural Science Foundation of Jiangsu Province(BK20220092).
文摘Mercury pollution,in conjunction with other contaminants,hampers progress toward the United Nations Sustainable Development Goals.The Minamata Convention on Mercury,which came into force in 2017,represents a critical step in combating this global issue.However,evaluating its effectiveness faces a major challenge,that is,establishing a clear link between reduced mercury emissions and lessened human exposure to neurotoxic methylmercury.Here,we propose that a previously overlooked methylmercury detoxification pathway in primary producers holds the potential to bridge the gaps in the emission-exposure nexus.A comprehensive understanding of this in vivo methylmercury demethylation and mercury reduction will enhance the effectiveness of global mercury mitigation efforts,accelerating our pace toward a sustainable future.
基金supported by the Youth Innovation Promotion Association,Chinese Academy of Sciences(2020314)the National Natural Science Foundation of China(41977355)+1 种基金China Postdoctoral Science Foundation(2021M703303)the USDA Hatch program(MAS 00549).
文摘There are increasing concerns over the threat of nanoplastics to environmental and human health.However,multidisciplinary barriers persist between the communities assessing the risks to environmental and human health.As a result,the hazards and risks of nanoplastics remain uncertain.Here,we identify key knowledge gaps by evaluating the exposure of nanoplastics in the environment,assessing their bio-nano interactions,and examining their potential risks to humans and the environment.We suggest considering nanoplastics a complex and dynamic mixture of polymers,additives,and contaminants,with interconnected risks to environmental and human health.We call for comprehensive integration of One Health approach to produce robust multidisciplinary evidence to nanoplastics threats at the planetary level.Although there are many challenges,this holistic approach incorporates the relevance of environmental exposure and multi-sectoral responses,which provide the opportunity to identify the risk mitigation strategies of nanoplastics to build resilient health systems.