BACKGROUND To report on the use of percutaneous hydrochloric acid(HCl) enhanced radiofrequency ablation(HRFA) for the treatment of large(maximum diameter ≥5 cm) hepatocellular carcinoma(HCC) in the caudate lobe.CASE ...BACKGROUND To report on the use of percutaneous hydrochloric acid(HCl) enhanced radiofrequency ablation(HRFA) for the treatment of large(maximum diameter ≥5 cm) hepatocellular carcinoma(HCC) in the caudate lobe.CASE SUMMARY Between August 2013 and June 2016, three patients with a large HCC(maximum diameter: 5.0, 5.7, and 8.1 cm) in the caudate lobe were treated by transarterial chemoembolization followed by computer tomography(CT) guided RFA using a monopolar perfusion RF electrode, which was enhanced by local infusion of 10%HCl at 0.2 mL/min(total volume, 3 to 12 mL). The output power of HRFA reached 100 W, and the average ablation time was 39 min(range, 15 to 60 min).Two patients each underwent one session of HRFA and one patient two sessions.After treatment, CT/magnetic resonance imaging showed that all the three lesions were completely ablated. There was no major complication. Two patients had asymptomatic bile duct dilatation. One patient died of tongue cancer 24 mo after ablation. The remaining two patients were alive and no area of enhancement is detected in the caudate lobe at 28 and 60 mo after ablation, respectively.CONCLUSION Percutaneous CT-guided HRFA is safe and efficacious in treating large HCC in the caudate lobe.展开更多
Transmittance and chromaticity are essential requirements for optical performance of thin-film transistor(TFT)arrays.However,it is still a challenge to get high transmittance and excellent chromaticity at the same tim...Transmittance and chromaticity are essential requirements for optical performance of thin-film transistor(TFT)arrays.However,it is still a challenge to get high transmittance and excellent chromaticity at the same time.In this paper,optimized optical design by using antireflection film theory and optical phase modulation is demonstrated in low temperature poly-silicon(LTPS)TFT arrays.To realize high transmittance,the refractive index difference of adjacent films is modified by using silicon oxynitride(SiOxNy)with adjustable refractive index.To realize excellent chromaticity,the thicknesses of multilayer films are precisely regulated for antireflection of certain wavelength light.The results show that the transmittance and chromaticity have been improved by about 6%and 18‰,respectively,at the same time,which is a big step forward for high optical performance of TFT arrays.The device characteristics of the TFT arrays with the optimal design,such as threshold voltage and electron mobility,are comparable to those of conventional TFT arrays.The optimized optical design results in enhanced power-conversion efficiencies and perfects the multilayer film design on the basic theory,which has great practicability to be applied in TFT arrays.展开更多
基金the National Natural Science Foundation of China,No.81771955
文摘BACKGROUND To report on the use of percutaneous hydrochloric acid(HCl) enhanced radiofrequency ablation(HRFA) for the treatment of large(maximum diameter ≥5 cm) hepatocellular carcinoma(HCC) in the caudate lobe.CASE SUMMARY Between August 2013 and June 2016, three patients with a large HCC(maximum diameter: 5.0, 5.7, and 8.1 cm) in the caudate lobe were treated by transarterial chemoembolization followed by computer tomography(CT) guided RFA using a monopolar perfusion RF electrode, which was enhanced by local infusion of 10%HCl at 0.2 mL/min(total volume, 3 to 12 mL). The output power of HRFA reached 100 W, and the average ablation time was 39 min(range, 15 to 60 min).Two patients each underwent one session of HRFA and one patient two sessions.After treatment, CT/magnetic resonance imaging showed that all the three lesions were completely ablated. There was no major complication. Two patients had asymptomatic bile duct dilatation. One patient died of tongue cancer 24 mo after ablation. The remaining two patients were alive and no area of enhancement is detected in the caudate lobe at 28 and 60 mo after ablation, respectively.CONCLUSION Percutaneous CT-guided HRFA is safe and efficacious in treating large HCC in the caudate lobe.
基金This work was supported by the Shenzhen Science and Technology Innovation(Grant No.JCYJ20180507181702150)the Guangdong Science and Technology Plan Project(Grant No.2019A050510011)the National Natural Science Foundation of China(Grant No.61504004).
文摘Transmittance and chromaticity are essential requirements for optical performance of thin-film transistor(TFT)arrays.However,it is still a challenge to get high transmittance and excellent chromaticity at the same time.In this paper,optimized optical design by using antireflection film theory and optical phase modulation is demonstrated in low temperature poly-silicon(LTPS)TFT arrays.To realize high transmittance,the refractive index difference of adjacent films is modified by using silicon oxynitride(SiOxNy)with adjustable refractive index.To realize excellent chromaticity,the thicknesses of multilayer films are precisely regulated for antireflection of certain wavelength light.The results show that the transmittance and chromaticity have been improved by about 6%and 18‰,respectively,at the same time,which is a big step forward for high optical performance of TFT arrays.The device characteristics of the TFT arrays with the optimal design,such as threshold voltage and electron mobility,are comparable to those of conventional TFT arrays.The optimized optical design results in enhanced power-conversion efficiencies and perfects the multilayer film design on the basic theory,which has great practicability to be applied in TFT arrays.
