Background:Diagnosis of Kounis syndrome,an acute coronary syndrome associatedwith anaphylactic reactions,is challenging owing to the overlapping symptoms ofmyocardial ischemia.Takotsubo syndrome(TTS),characterized by ...Background:Diagnosis of Kounis syndrome,an acute coronary syndrome associatedwith anaphylactic reactions,is challenging owing to the overlapping symptoms ofmyocardial ischemia.Takotsubo syndrome(TTS),characterized by stress-induced cardiomyopathy,may share pathophysiological mechanisms with Kounis syndrome and potentially coexist in the same patient.CasePresentation:We present a case of a 63-year-old patient who developed an allergic reaction to contrastmediumadministration,leading to dyspnea and chest pain.Electrocardiography revealed a new-onset left bundle-branch block,and echocardiography indicated wall motion abnormalities with apical ballooning,suggestive of TTS.Coronary angiography displayed a chronic total occlusion of the right coronary artery.Laboratory tests revealed elevated inflammatory markers,supporting the diagnosis of Kounis syndrome and TTS.Conclusion:This case highlights the challenges of diagnosing and managing type II Kounis syndrome associated with concurrent TTS.This underscores the need for tailored therapeutic interventions and comprehensive guidelines to address these complex conditions effectively.展开更多
文摘Background:Diagnosis of Kounis syndrome,an acute coronary syndrome associatedwith anaphylactic reactions,is challenging owing to the overlapping symptoms ofmyocardial ischemia.Takotsubo syndrome(TTS),characterized by stress-induced cardiomyopathy,may share pathophysiological mechanisms with Kounis syndrome and potentially coexist in the same patient.CasePresentation:We present a case of a 63-year-old patient who developed an allergic reaction to contrastmediumadministration,leading to dyspnea and chest pain.Electrocardiography revealed a new-onset left bundle-branch block,and echocardiography indicated wall motion abnormalities with apical ballooning,suggestive of TTS.Coronary angiography displayed a chronic total occlusion of the right coronary artery.Laboratory tests revealed elevated inflammatory markers,supporting the diagnosis of Kounis syndrome and TTS.Conclusion:This case highlights the challenges of diagnosing and managing type II Kounis syndrome associated with concurrent TTS.This underscores the need for tailored therapeutic interventions and comprehensive guidelines to address these complex conditions effectively.