Background:The prevalence of type 2 diabetes mellitus(T2DM)has been rapidly growing in Chinese populations in recent decades,and the shift in eating habits is a key contributing factor to this increase.Eating out of h...Background:The prevalence of type 2 diabetes mellitus(T2DM)has been rapidly growing in Chinese populations in recent decades,and the shift in eating habits is a key contributing factor to this increase.Eating out of home(EOH)is one of the major shifts in eating habits during this period.However,the influence of EOH on the incidence of T2DM among Chinese urban workers is unknown.Methods:The cross-sectional study involved an analysis of 13,904 urban workers recruited from 11 health examination centers in the major cities of China to explore the relationship between EOH and T2DM between 2013 September and 2016 March.Results:Average weekly EOH frequency≥10 times was positively associated with increased incidence of T2DM in the sampled population(OR:1.31[1.11-1.54],p<0.01),most notably in participants≤45 years old(OR:1.41[1.11-1.80],p<0.01])and in males(OR:1.26[1.06-1.51],p<0.01).An EOH frequency of 5 times/week appears as a threshold for a significant increase in the odds of T2DM.Weekly EOH frequency≥5 times was associated with increased odds of T2DM in a dose-response manner in the total population and almost all subgroups(poverall association<0.05 andpnonlinearity≤0.05).Conclusion:This study showed that a frequency of EOH(≥5 times/week)was associated with a frequency-dependent increase in the odds of T2DM urban workers in China.More nutrition promotion is needed to improve the eating behavior of Chinese urban workers to reduce T2DM risk.展开更多
The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species. Here, we report the transcriptomes ofA. lucorum at three different developmental stages （the ...The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species. Here, we report the transcriptomes ofA. lucorum at three different developmental stages （the second and fifth instar nymphs and adults）. A total of 98,236 unigenes with an average length of 1,335nt was obtained, of which 50,640 were annotated, including those encoding digestive enzymes and cytochrome P450s. Comparisons with cotton bollworm and cotton aphid transcriptomes revealed distinct features ofA. lucorum as a mesophyll feeder. The gene expression dynamics varied during development from young nymphs to adults. The high-quality transcriptome data and the gene expression dynamics reported here provide valuable data for a more comprehensive understanding of the physiology and development of mirid bugs, and for mining targets for their control.展开更多
基金National Nutrition Science Research Grant(Grant/Award Number:CNS-NNSRG2019-234)Chinese National Key Research and Development Program during the 13th Five-year Plan Period(Grant/Award Number:2022YFC2010106)+2 种基金Disciplines Construction Project of Peking Union Medical College(Grant/Award Number:PUMC,201920202102)National Natural Science Foundation of China(Grant/Award Number:81971316)National High Level Hospital Clinical Research Funding(Grant/Award Number:bj-2023-72)。
文摘Background:The prevalence of type 2 diabetes mellitus(T2DM)has been rapidly growing in Chinese populations in recent decades,and the shift in eating habits is a key contributing factor to this increase.Eating out of home(EOH)is one of the major shifts in eating habits during this period.However,the influence of EOH on the incidence of T2DM among Chinese urban workers is unknown.Methods:The cross-sectional study involved an analysis of 13,904 urban workers recruited from 11 health examination centers in the major cities of China to explore the relationship between EOH and T2DM between 2013 September and 2016 March.Results:Average weekly EOH frequency≥10 times was positively associated with increased incidence of T2DM in the sampled population(OR:1.31[1.11-1.54],p<0.01),most notably in participants≤45 years old(OR:1.41[1.11-1.80],p<0.01])and in males(OR:1.26[1.06-1.51],p<0.01).An EOH frequency of 5 times/week appears as a threshold for a significant increase in the odds of T2DM.Weekly EOH frequency≥5 times was associated with increased odds of T2DM in a dose-response manner in the total population and almost all subgroups(poverall association<0.05 andpnonlinearity≤0.05).Conclusion:This study showed that a frequency of EOH(≥5 times/week)was associated with a frequency-dependent increase in the odds of T2DM urban workers in China.More nutrition promotion is needed to improve the eating behavior of Chinese urban workers to reduce T2DM risk.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences(XDB11030000)the Ministry of Agriculture of China(2014ZX08009001-009)
文摘The green mirid bug Apolygus lucorum is an agricultural pest that is known to cause damage to more than 150 plant species. Here, we report the transcriptomes ofA. lucorum at three different developmental stages （the second and fifth instar nymphs and adults）. A total of 98,236 unigenes with an average length of 1,335nt was obtained, of which 50,640 were annotated, including those encoding digestive enzymes and cytochrome P450s. Comparisons with cotton bollworm and cotton aphid transcriptomes revealed distinct features ofA. lucorum as a mesophyll feeder. The gene expression dynamics varied during development from young nymphs to adults. The high-quality transcriptome data and the gene expression dynamics reported here provide valuable data for a more comprehensive understanding of the physiology and development of mirid bugs, and for mining targets for their control.
