Cranberry polyphenols(CPs)were obtained via ultrasound-assisted extraction and purification on a macroporous resin X-5 column.A green synthesis method of selenium nanoparticles(SeNPs)using CPs as reducing agents was t...Cranberry polyphenols(CPs)were obtained via ultrasound-assisted extraction and purification on a macroporous resin X-5 column.A green synthesis method of selenium nanoparticles(SeNPs)using CPs as reducing agents was then developed.Two types of SeNPs(CP-SeNPs1 and CP-SeNPs2)were successfully constructed and character-ized.The spherical particles were well-dispersed on the polyphenol templates and the addition of the poly-phenols reduced the aggregation of the nanoparticles.Both CP-SeNPs1 and CP-SeNPs2,with average particle sizes of 85.62±0.11 nm and 107.97±0.12 nm,respectively,demonstrated radical-scavenging activities and protective effects on erythrocyte hemolysis.CP-SeNPs2 possessed more significant antioxidant activity,as evi-denced by its higher radical-scavenging rate and greater enhancement of the erythrocyte antioxidant state compared to those of CP-SeNPs1.This study provides a new application of CPs and confirms their great potential in stabilizing SeNPs.展开更多
基金supported by National-Local Joint Engineering Research Center for Development and Utilization of Small Fruits in Cold Regions(2023GCZX002)Student's Innovation Training Program of Heilongjiang Province(S202310224060).
文摘Cranberry polyphenols(CPs)were obtained via ultrasound-assisted extraction and purification on a macroporous resin X-5 column.A green synthesis method of selenium nanoparticles(SeNPs)using CPs as reducing agents was then developed.Two types of SeNPs(CP-SeNPs1 and CP-SeNPs2)were successfully constructed and character-ized.The spherical particles were well-dispersed on the polyphenol templates and the addition of the poly-phenols reduced the aggregation of the nanoparticles.Both CP-SeNPs1 and CP-SeNPs2,with average particle sizes of 85.62±0.11 nm and 107.97±0.12 nm,respectively,demonstrated radical-scavenging activities and protective effects on erythrocyte hemolysis.CP-SeNPs2 possessed more significant antioxidant activity,as evi-denced by its higher radical-scavenging rate and greater enhancement of the erythrocyte antioxidant state compared to those of CP-SeNPs1.This study provides a new application of CPs and confirms their great potential in stabilizing SeNPs.
