AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwan Residents military male cohort.METHODS We made a cross-sectional examination of this associa...AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwan Residents military male cohort.METHODS We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study.Cases of chronic hepatitis B(n=121)were defined by personal history and positive detection of hepatitis B surface antigen.Cases of nonalcoholic steatohepatitis(n=129)were defined by alanine transaminase level>60 U/L,liver ultrasound finding of steatosis,and absence of viral hepatitis A,B or C infection.All other study participants were defined as unaffected(n=3419).Physical fitness was evaluated by performance in 3000-m run,2-min sit-ups,and 2-min push-ups exercises,with all the procedures standardized by a computerized scoring system.Multiple linear regression analysis was used to determine the relationship.RESULTS Chronic hepatitis B negatively correlated with 2-min push-up numbers(β=-2.49,P=0.019)after adjusting for age,service specialty,body mass index,systolic and diastolic blood pressures,current cigarette smoking,alcohol intake status,serum hemoglobin,and average weekly exercise times.Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time(β=11.96,P=0.084)and negatively correlated with 2-min sit-up numbers(β=-1.47,P=0.040).CONCLUSION Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males,and future study should determine the underlying mechanism.展开更多
基金Supported by research grants from the Hualien-Armed Forces General Hospital,No.805-C105-10the Ministry of National Defense-Medical Affairs Bureau,No.MAB-106-124
文摘AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwan Residents military male cohort.METHODS We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study.Cases of chronic hepatitis B(n=121)were defined by personal history and positive detection of hepatitis B surface antigen.Cases of nonalcoholic steatohepatitis(n=129)were defined by alanine transaminase level>60 U/L,liver ultrasound finding of steatosis,and absence of viral hepatitis A,B or C infection.All other study participants were defined as unaffected(n=3419).Physical fitness was evaluated by performance in 3000-m run,2-min sit-ups,and 2-min push-ups exercises,with all the procedures standardized by a computerized scoring system.Multiple linear regression analysis was used to determine the relationship.RESULTS Chronic hepatitis B negatively correlated with 2-min push-up numbers(β=-2.49,P=0.019)after adjusting for age,service specialty,body mass index,systolic and diastolic blood pressures,current cigarette smoking,alcohol intake status,serum hemoglobin,and average weekly exercise times.Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time(β=11.96,P=0.084)and negatively correlated with 2-min sit-up numbers(β=-1.47,P=0.040).CONCLUSION Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males,and future study should determine the underlying mechanism.
