<strong><span style="font-family:Verdana;">Background:</span></strong> <span style="white-space:normal;font-family:Verdana;" "="">Pulmonary vein isolati...<strong><span style="font-family:Verdana;">Background:</span></strong> <span style="white-space:normal;font-family:Verdana;" "="">Pulmonary vein isolation by means of cryoballoon is a well-es</span><span style="white-space:normal;font-family:Verdana;" "="">tablished way of treatment of atrial fibrillation. The aim of the study was to compare the acute cryoballoon biophysical parameters attained during energy applications to </span><span style="white-space:normal;font-family:Verdana;" "="">the </span><span style="white-space:normal;font-family:Verdana;" "="">individual pulmonary vein during sinus rhythm versus</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;"> atrial fibrillation. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">100 </span><b></b><span style="font-family:Verdana;">Patients who underwent their first</span></span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:Verdana;" "="">time PVI using second</span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;">generation cryoballoon for symptomatic and drug-refractory AF, between the beginning of March to end of August 2016, were initially screened. 61 patients with paroxysmal AF were included in the present study. 39 patients with persistent AF were excluded. No pre-procedural anatomical imaging was reported. </span><b><span style="font-family:Verdana;">Results</span></b><span style="font-family:Verdana;">: A total of 61 patients (male 80%, age 59.3</span></span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">± 13.4 years) </span><span style="white-space:normal;font-family:Verdana;" "="">were included in the present analysis. </span><span style="white-space:normal;font-family:Verdana;" "="">A </span><span style="white-space:normal;font-family:Verdana;" "="">total of 243 pulmonary veins were </span><span style="white-space:normal;font-family:Verdana;" "="">isolated with an average of 1.87</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">± 1.14 cryo</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">energy applications per individual vein. During cryo application, there were no significant difference</span><span style="white-space:normal;font-family:Verdana;" "="">s</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;"> between applications delivered during sinus rhythm or ongoing AF in the rate of temperature drop at 5 and 30 s, rate of warming at 5 s after freezing stop or achieved balloon nadir temperature. The same also was observed for both the balloon cooling rate and warming times. </span><b><span style="font-family:Verdana;">Conclusions: </span></b><span style="font-family:Verdana;">The present analysis shows no impact of the patient baseline rhythm at the time of energy application upon the acute balloon biophysical parameters in patients with normal sinus rhythm and those with ongoing atrial fibrillation using the second</span></span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:Verdana;" "="">generation cryo</span><span style="white-space:normal;font-family:Verdana;" "="">balloon.</span>展开更多
文摘<strong><span style="font-family:Verdana;">Background:</span></strong> <span style="white-space:normal;font-family:Verdana;" "="">Pulmonary vein isolation by means of cryoballoon is a well-es</span><span style="white-space:normal;font-family:Verdana;" "="">tablished way of treatment of atrial fibrillation. The aim of the study was to compare the acute cryoballoon biophysical parameters attained during energy applications to </span><span style="white-space:normal;font-family:Verdana;" "="">the </span><span style="white-space:normal;font-family:Verdana;" "="">individual pulmonary vein during sinus rhythm versus</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;"> atrial fibrillation. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">100 </span><b></b><span style="font-family:Verdana;">Patients who underwent their first</span></span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:Verdana;" "="">time PVI using second</span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;">generation cryoballoon for symptomatic and drug-refractory AF, between the beginning of March to end of August 2016, were initially screened. 61 patients with paroxysmal AF were included in the present study. 39 patients with persistent AF were excluded. No pre-procedural anatomical imaging was reported. </span><b><span style="font-family:Verdana;">Results</span></b><span style="font-family:Verdana;">: A total of 61 patients (male 80%, age 59.3</span></span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">± 13.4 years) </span><span style="white-space:normal;font-family:Verdana;" "="">were included in the present analysis. </span><span style="white-space:normal;font-family:Verdana;" "="">A </span><span style="white-space:normal;font-family:Verdana;" "="">total of 243 pulmonary veins were </span><span style="white-space:normal;font-family:Verdana;" "="">isolated with an average of 1.87</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">± 1.14 cryo</span><span style="white-space:normal;font-family:;" "=""> </span><span style="white-space:normal;font-family:Verdana;" "="">energy applications per individual vein. During cryo application, there were no significant difference</span><span style="white-space:normal;font-family:Verdana;" "="">s</span><span style="white-space:normal;font-family:;" "=""><span style="font-family:Verdana;"> between applications delivered during sinus rhythm or ongoing AF in the rate of temperature drop at 5 and 30 s, rate of warming at 5 s after freezing stop or achieved balloon nadir temperature. The same also was observed for both the balloon cooling rate and warming times. </span><b><span style="font-family:Verdana;">Conclusions: </span></b><span style="font-family:Verdana;">The present analysis shows no impact of the patient baseline rhythm at the time of energy application upon the acute balloon biophysical parameters in patients with normal sinus rhythm and those with ongoing atrial fibrillation using the second</span></span><span style="white-space:normal;font-family:Verdana;" "="">-</span><span style="white-space:normal;font-family:Verdana;" "="">generation cryo</span><span style="white-space:normal;font-family:Verdana;" "="">balloon.</span>
