Aim:The safety and efficacy of the endovascular recanalisation therapy(ERT)for a-cute ischemic stroke caused by proximal intracerebral occlusion of the anterior circulation has been proved.Due to the high mortality an...Aim:The safety and efficacy of the endovascular recanalisation therapy(ERT)for a-cute ischemic stroke caused by proximal intracerebral occlusion of the anterior circulation has been proved.Due to the high mortality and disability of Acute VBAO,more attention has been attached to endovascular recanalisation therapy.However,the effectiveness of ERT for Acute completely VBAO was not well demonstrated.Methods:The clinical and angiographic data of 13 patients who received ERT for acute posterior circulation ischemic stroke caused by acute completely VBAO in our endovascular database from 2011 to 2015 were retrospectively analyzed.Successful recanalisation was defined as Thrombolysis in Cerebral Infarction(TICI)grade≥2b.The modified Rankin scale(mRS)score was used to measure outcome.Results:13 patients with a mean age of 62.5 years were included in the study(11 men and 2 women).The mean time from symptom onset to treatment was(539.0±267.7)min.The National Institutes of Health Stroke Scale(NIHSS)and GlasgowComa Scale(GCS)score on admission were 21.1(range 6-30)and 8.6(range 4-14),respectively.Recanalization(TICI≥2b)was successful in 11 of our 13 patients(84.6%),with the TICI grade of 3 in six patients and 2b in five patients.One patient(7.7%)suffered a symptomatic intracerebral hemorrhage.At 3 months,38.5%(5/13)overall had good and moderate outcome(mRS≤3);42.8.5%of patients treated with an Solitaire stent retrievers procedure as the initial ERT and 16.7%of patients treated with IAT as the initial ERT had good outcome(mRS≤2).The overall mortality rate was 53.8%(7 of 13)at 3 months.Conclusions:ERT may be effective and safe for acute completely vertebrobasilar artery occlusion(VBAO)in acute posterior circulation ischemic stroke patients;the Solitaire stent retrievers procedure(compared to intra-arterial thrombolysis,IAT)may have greater efficacy and safety.展开更多
基金Supported by National Natural Science Foundation of China(81271280)
文摘Aim:The safety and efficacy of the endovascular recanalisation therapy(ERT)for a-cute ischemic stroke caused by proximal intracerebral occlusion of the anterior circulation has been proved.Due to the high mortality and disability of Acute VBAO,more attention has been attached to endovascular recanalisation therapy.However,the effectiveness of ERT for Acute completely VBAO was not well demonstrated.Methods:The clinical and angiographic data of 13 patients who received ERT for acute posterior circulation ischemic stroke caused by acute completely VBAO in our endovascular database from 2011 to 2015 were retrospectively analyzed.Successful recanalisation was defined as Thrombolysis in Cerebral Infarction(TICI)grade≥2b.The modified Rankin scale(mRS)score was used to measure outcome.Results:13 patients with a mean age of 62.5 years were included in the study(11 men and 2 women).The mean time from symptom onset to treatment was(539.0±267.7)min.The National Institutes of Health Stroke Scale(NIHSS)and GlasgowComa Scale(GCS)score on admission were 21.1(range 6-30)and 8.6(range 4-14),respectively.Recanalization(TICI≥2b)was successful in 11 of our 13 patients(84.6%),with the TICI grade of 3 in six patients and 2b in five patients.One patient(7.7%)suffered a symptomatic intracerebral hemorrhage.At 3 months,38.5%(5/13)overall had good and moderate outcome(mRS≤3);42.8.5%of patients treated with an Solitaire stent retrievers procedure as the initial ERT and 16.7%of patients treated with IAT as the initial ERT had good outcome(mRS≤2).The overall mortality rate was 53.8%(7 of 13)at 3 months.Conclusions:ERT may be effective and safe for acute completely vertebrobasilar artery occlusion(VBAO)in acute posterior circulation ischemic stroke patients;the Solitaire stent retrievers procedure(compared to intra-arterial thrombolysis,IAT)may have greater efficacy and safety.
