目的探讨脑梗死合并亚临床甲状腺功能减退(亚甲减)病人甲状腺功能与24 h尿蛋白、血同型半胱氨酸的关系。方法入选2011年1月至2017年7月海南省人民医院老年病科脑梗死病人200例。按甲状腺功能将其分为4组:对照组40例[脑梗死合并甲状腺功...目的探讨脑梗死合并亚临床甲状腺功能减退(亚甲减)病人甲状腺功能与24 h尿蛋白、血同型半胱氨酸的关系。方法入选2011年1月至2017年7月海南省人民医院老年病科脑梗死病人200例。按甲状腺功能将其分为4组:对照组40例[脑梗死合并甲状腺功能正常,即游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺激素(TSH)均正常]、轻度亚临床甲减组60例(FT3、FT4正常,4 m IU/L≤TSH<10 m IU/L)、重度亚甲减组60例(FT3、FT4正常,TSH≥10 m IU/L)、临床甲减组40例(FT3、FT4降低,TSH≥4 m IU/L)。其中轻度亚甲减组及重度亚甲减组的病人均分别再随机分为服药亚组和未服药亚组,各亚组均为30例。2个未服药亚组采用常规治疗,2个服药亚组加用左甲状腺素片治疗6个月。记录病人的年龄、性别、血压、血糖、血脂、甲状腺功能等,比较4组24 h尿蛋白、血同型半胱氨酸水平的差异。结果 4组病人年龄、性别、血压、血糖、血脂差异无统计学意义(P>0. 05)。脑梗死合并重度亚甲减组、临床甲减组24 h尿蛋白水平较对照组明显升高(P<0. 05)。重度亚甲减服药亚组6个月时24 h尿蛋白、同型半胱氨酸水平较重度亚甲减未服药亚组降低(P<0. 05)。结论对脑梗死病人应积极筛查甲状腺功能,及早发现和干预重度亚甲减,以减少肾损害和心脑血管疾病风险。展开更多
Fourteen soil properties in 17 sampling sites were analyzed to study the soil degradation in a magnesite mining area in Halcheng City, Northeast China. Such areas have hitherto received little attention. The current p...Fourteen soil properties in 17 sampling sites were analyzed to study the soil degradation in a magnesite mining area in Halcheng City, Northeast China. Such areas have hitherto received little attention. The current practices of magnesite mining in this area resulted in degradation of soil quality and specifically led to an increase in soil pH, the ratio of magnesium to calcium, bulk density, clay dispersibility, total magnesium and equivalent calcium carbonate and a decrease in surface soil porosity and available phosphorous. The soil quality in the areas affected by intensive mining activity was obviously worse than that of areas far away from the mine. Four factors were identified and ＂magnesium factor＂, ＂pH factor＂ and ＂fertility factor＂, involving 13 soil properties, explained 82~0 of the total variance in the entire data set. Discriminant analysis showed that the total magnesium, water-soluble calcium and available phosphorous were the most sensitive indicators for soil quality.展开更多
文摘目的探讨脑梗死合并亚临床甲状腺功能减退(亚甲减)病人甲状腺功能与24 h尿蛋白、血同型半胱氨酸的关系。方法入选2011年1月至2017年7月海南省人民医院老年病科脑梗死病人200例。按甲状腺功能将其分为4组:对照组40例[脑梗死合并甲状腺功能正常,即游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及促甲状腺激素(TSH)均正常]、轻度亚临床甲减组60例(FT3、FT4正常,4 m IU/L≤TSH<10 m IU/L)、重度亚甲减组60例(FT3、FT4正常,TSH≥10 m IU/L)、临床甲减组40例(FT3、FT4降低,TSH≥4 m IU/L)。其中轻度亚甲减组及重度亚甲减组的病人均分别再随机分为服药亚组和未服药亚组,各亚组均为30例。2个未服药亚组采用常规治疗,2个服药亚组加用左甲状腺素片治疗6个月。记录病人的年龄、性别、血压、血糖、血脂、甲状腺功能等,比较4组24 h尿蛋白、血同型半胱氨酸水平的差异。结果 4组病人年龄、性别、血压、血糖、血脂差异无统计学意义(P>0. 05)。脑梗死合并重度亚甲减组、临床甲减组24 h尿蛋白水平较对照组明显升高(P<0. 05)。重度亚甲减服药亚组6个月时24 h尿蛋白、同型半胱氨酸水平较重度亚甲减未服药亚组降低(P<0. 05)。结论对脑梗死病人应积极筛查甲状腺功能,及早发现和干预重度亚甲减,以减少肾损害和心脑血管疾病风险。
基金Supported by the Knowledge Innovative Program of the Chinese Academy of Sciences (No. KZCX2-YW-446)the National NaturalScience Foundation of China (No. 40930739)+1 种基金the Key Program of Action Plan for Revitalizing Northeast China with Science andTechnology of the Chinese Academy of Sciences (No. DB2X-2-027)the National Environmental Protection Commonwealth Projectof China (No. 200809047)
文摘Fourteen soil properties in 17 sampling sites were analyzed to study the soil degradation in a magnesite mining area in Halcheng City, Northeast China. Such areas have hitherto received little attention. The current practices of magnesite mining in this area resulted in degradation of soil quality and specifically led to an increase in soil pH, the ratio of magnesium to calcium, bulk density, clay dispersibility, total magnesium and equivalent calcium carbonate and a decrease in surface soil porosity and available phosphorous. The soil quality in the areas affected by intensive mining activity was obviously worse than that of areas far away from the mine. Four factors were identified and ＂magnesium factor＂, ＂pH factor＂ and ＂fertility factor＂, involving 13 soil properties, explained 82~0 of the total variance in the entire data set. Discriminant analysis showed that the total magnesium, water-soluble calcium and available phosphorous were the most sensitive indicators for soil quality.
