Poly（ethylene glycol） methacrylate （PEGMA） was introduced into a polyurethane （PU） solution in order to prepare hemocom- patible electrospun membranes for potential application as small diameter vascular scaffol...Poly（ethylene glycol） methacrylate （PEGMA） was introduced into a polyurethane （PU） solution in order to prepare hemocom- patible electrospun membranes for potential application as small diameter vascular scaffolds. Crosslinked PU/PEGMA hybrid nanofibers were fabricated by a reactive electrospinning process with N,N＇-methylenebisacrylamide （MBAm） as erosslinker and benzophenone （BP） as photoinitiator. The photoinduced polymerization and crosslinking reaction took place simultane- ously during the electrospinning process. No significant difference in the membrane morphology was found by SEM when PEGMA content was less than 20 wt%. The crosslinked fibrous membranes of PU/PEGMA exhibit higher hydro- philicity and mechanical strength than PU membrane. These nanofibrous membranes are potential substitutes for artificial vascular scaffolds.展开更多
基金financially supported by the Program for New Century Excellent Talents in University "NCET"Ministry of Education of Chinathe International Cooperation from Ministry of Science and Technology of China (Grant No. 2008DFA51170)
文摘Poly（ethylene glycol） methacrylate （PEGMA） was introduced into a polyurethane （PU） solution in order to prepare hemocom- patible electrospun membranes for potential application as small diameter vascular scaffolds. Crosslinked PU/PEGMA hybrid nanofibers were fabricated by a reactive electrospinning process with N,N＇-methylenebisacrylamide （MBAm） as erosslinker and benzophenone （BP） as photoinitiator. The photoinduced polymerization and crosslinking reaction took place simultane- ously during the electrospinning process. No significant difference in the membrane morphology was found by SEM when PEGMA content was less than 20 wt%. The crosslinked fibrous membranes of PU/PEGMA exhibit higher hydro- philicity and mechanical strength than PU membrane. These nanofibrous membranes are potential substitutes for artificial vascular scaffolds.
