Postoperative bleeding(POB)is a major complication following pancreaticoduodenectomy(PD),leading to significant morbidity and potential mortality.This minireview focuses on the prevention and management strategies for...Postoperative bleeding(POB)is a major complication following pancreaticoduodenectomy(PD),leading to significant morbidity and potential mortality.This minireview focuses on the prevention and management strategies for POB,synthesizing current evidence on surgical techniques,perioperative management,and postoperative interventions.Effective prevention strategies include the use of regional vessel wrapping,optimal pancreatic anastomosis,and meticulous intraoperative hemostasis.Postoperative management strategies,such as early detection using predictive models and advanced imaging,along with endovascular interventions like angiographic embolization and stent graft placement,are essential for timely intervention.Risk factors,including pancreatic texture,anticoagulation therapy,and patient comorbidities,further influence bleeding outcomes.The minireview also identifies gaps in current research and emphasizes the need for prospective randomized controlled trials to establish standardized protocols.Overall,a multidisciplinary approach combining surgical expertise,predictive analytics,and personalized care is essential to improving patient out comes and minimizing the risk of POB following PD.展开更多
Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of prot...Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of proton transport in transition metal oxides,which dates back to 1971[3]when RuO_(2) was discovered to be capable of storing protons via reversible redox reactions[4].In aqueous electrolytes,the thin film RuO_(2) electrode exhibits a surface pseudocapacitive behavior[5],which could be modified by the structural water in its hydrated form due to the facile Grotthuss hopping mode of protons along the established hydrogen bonds inside the bulk phase[6].Soon later,Goodenough et al.reported the capacitor-like behavior of amorphous MnO_(2)·xH_(2)O electrode in an aqueous KCl electrolyte[7],and further studies on the hydrated MnO_(2) electrodes prepared by sol-gel processes have soon discovered that the intercalation of protons from aqueous electrolytes plays an indispensable role in the charge storage mechanism[8].In recent years,the research interest on rechargeable aqueous batteries has fueled the renaissance of mechanistic study of proton transport in transition metal oxides[9],which can operate as cathodes or anodes via a topotactic insertion mechanism similar to that in Li-ion batteries[10].However,due to the challenges for experimental detection of local chemical environments of the inserted protons,a comprehensive understanding of proton dynamic behavior in these electrodes remains largely lacking.展开更多
We examined the enhancing effects of different dosages of product of Centrifugation of Bacterial Liquid(product of CBL)on the performance of slag-fGD gypsum-cement-bentonite-sludge system using MICP technology.We anal...We examined the enhancing effects of different dosages of product of Centrifugation of Bacterial Liquid(product of CBL)on the performance of slag-fGD gypsum-cement-bentonite-sludge system using MICP technology.We analyzed the multifaceted performance of the solidified sludge from macroscopic and microscopic perspectives.The experimental results reveal that the increase in product of CBL dosage results in positive impacts on the solidified sludge,including higher side compressive strength,lower leachate heavy metal concentration,and improved crack repair rates.At a 0.4%product of CBL doping concentration,the strength of the solidified sludge is enhanced by 26.6%at 3 d,61.2%at 7 d,and 13.9%at 28 d when compared to the unmodified solidified sludge.After 28 days,the concentrations of Zn and Cu ions reduce by 58%and 18%,respectively,and the crack repair rate is 58.4%.These results demonstrate that the increase in heavy metal concentration in the leachate leads to an increase in the strength of the solidified sludge.The strengthening procedure heavily relies on the mineralisation reaction of Bacillus pasteurii,which produces a substantial amount of CaCO_(3)to cement the particles and fill the pores initially.The modified solidifying sludge exhibits a self-repairing effect and an enhanced multifaceted performance as a result of oxygen being restored after crack formation and reactivation of Bacillus pasteurii.Such conditions facilitate the body's recovery.展开更多
文摘Postoperative bleeding(POB)is a major complication following pancreaticoduodenectomy(PD),leading to significant morbidity and potential mortality.This minireview focuses on the prevention and management strategies for POB,synthesizing current evidence on surgical techniques,perioperative management,and postoperative interventions.Effective prevention strategies include the use of regional vessel wrapping,optimal pancreatic anastomosis,and meticulous intraoperative hemostasis.Postoperative management strategies,such as early detection using predictive models and advanced imaging,along with endovascular interventions like angiographic embolization and stent graft placement,are essential for timely intervention.Risk factors,including pancreatic texture,anticoagulation therapy,and patient comorbidities,further influence bleeding outcomes.The minireview also identifies gaps in current research and emphasizes the need for prospective randomized controlled trials to establish standardized protocols.Overall,a multidisciplinary approach combining surgical expertise,predictive analytics,and personalized care is essential to improving patient out comes and minimizing the risk of POB following PD.
基金financial support from the National Natural Science Foundation of China(22109003)the Basic and Applied Basic Research Foundation of Guangdong Province(2023A1515011391)+1 种基金Soft Science Research Project of Guangdong Province(No.2017B030301013)the Major Science and Technology Infrastructure Project of Material Genome Big-science Facilities Platform supported by Municipal Development and Reform Commission of Shenzhen.
文摘Understanding the proton dynamic behavior in inorganic materials has long been a topic of intense fascination[1],especially in the field of electrochemical energy storage[2].One of the examples is the research of proton transport in transition metal oxides,which dates back to 1971[3]when RuO_(2) was discovered to be capable of storing protons via reversible redox reactions[4].In aqueous electrolytes,the thin film RuO_(2) electrode exhibits a surface pseudocapacitive behavior[5],which could be modified by the structural water in its hydrated form due to the facile Grotthuss hopping mode of protons along the established hydrogen bonds inside the bulk phase[6].Soon later,Goodenough et al.reported the capacitor-like behavior of amorphous MnO_(2)·xH_(2)O electrode in an aqueous KCl electrolyte[7],and further studies on the hydrated MnO_(2) electrodes prepared by sol-gel processes have soon discovered that the intercalation of protons from aqueous electrolytes plays an indispensable role in the charge storage mechanism[8].In recent years,the research interest on rechargeable aqueous batteries has fueled the renaissance of mechanistic study of proton transport in transition metal oxides[9],which can operate as cathodes or anodes via a topotactic insertion mechanism similar to that in Li-ion batteries[10].However,due to the challenges for experimental detection of local chemical environments of the inserted protons,a comprehensive understanding of proton dynamic behavior in these electrodes remains largely lacking.
基金Funded by the National Nature Science Foundation of China(Nos.51978439,52278269,52278268,and 52108238)the Tianjin Outstanding Young Scholars Science Fund Project(No.22JCJQJC00020)the State Key Laboratory of Green Building Materials Open Foundation(No.2021GBM08)。
文摘We examined the enhancing effects of different dosages of product of Centrifugation of Bacterial Liquid(product of CBL)on the performance of slag-fGD gypsum-cement-bentonite-sludge system using MICP technology.We analyzed the multifaceted performance of the solidified sludge from macroscopic and microscopic perspectives.The experimental results reveal that the increase in product of CBL dosage results in positive impacts on the solidified sludge,including higher side compressive strength,lower leachate heavy metal concentration,and improved crack repair rates.At a 0.4%product of CBL doping concentration,the strength of the solidified sludge is enhanced by 26.6%at 3 d,61.2%at 7 d,and 13.9%at 28 d when compared to the unmodified solidified sludge.After 28 days,the concentrations of Zn and Cu ions reduce by 58%and 18%,respectively,and the crack repair rate is 58.4%.These results demonstrate that the increase in heavy metal concentration in the leachate leads to an increase in the strength of the solidified sludge.The strengthening procedure heavily relies on the mineralisation reaction of Bacillus pasteurii,which produces a substantial amount of CaCO_(3)to cement the particles and fill the pores initially.The modified solidifying sludge exhibits a self-repairing effect and an enhanced multifaceted performance as a result of oxygen being restored after crack formation and reactivation of Bacillus pasteurii.Such conditions facilitate the body's recovery.
