目的基于数据挖掘探讨裴晓华教授治疗非哺乳期乳腺炎的用药规律。方法收集2021年4月至2023年12月裴晓华教授于北京中医药大学东直门医院厦门医院国际门诊部看诊非哺乳期乳腺炎患者的病历。采用Excel 2019描述药物频次、性味、归经。采用...目的基于数据挖掘探讨裴晓华教授治疗非哺乳期乳腺炎的用药规律。方法收集2021年4月至2023年12月裴晓华教授于北京中医药大学东直门医院厦门医院国际门诊部看诊非哺乳期乳腺炎患者的病历。采用Excel 2019描述药物频次、性味、归经。采用R studio 4.3.3软件分析关联规则、聚类,比较月经异常组、未诉月经异常组处方间Jaccard系数、组内φ系数,并进行可视化。结果本研究共发现1020首处方涉及226味中药,总频次为14765次,高频药物有甘草、当归、川芎等;药性以温、寒、平为主,药味以苦、甘、辛为主,归经以肝、脾、肺经最多。关联规则分析显示,黄芪-川芎-白芷-当归关联密切,药对川芎-当归参与构成药物组合最多。聚类分析得到6类药对或新方。组间比较发现,92.36%的Jaccard系数<0.5,炒麦芽-焦山楂、醋乳香-醋没药为特殊药对。结论裴晓华教授治疗非哺乳期乳腺炎组方规律为重视内调外透,善调女子冲任气血,对临床治疗和传承有重要意义。展开更多
Chinese medicated bath is one of the external therapies in Traditional Chinese Medicine(TCM),which has been widely used clinically.The“International Standard of Traditional Chinese Medicine Techniques:The Operating S...Chinese medicated bath is one of the external therapies in Traditional Chinese Medicine(TCM),which has been widely used clinically.The“International Standard of Traditional Chinese Medicine Techniques:The Operating Specifications for Chinese Medicated Bath”is drawn up by the Beijing University of Chinese Medicine Third Affiliated Hospital and Beijing University of Chinese Medicine Xiamen Hospital in collaboration with domestic TCM universities and hospitals.The specification includes definition,operating process,points for attention and contraindications.It is targeted to provide reference for TCM providers at home and abroad with TCM background in clinical decision-making.展开更多
文摘目的基于数据挖掘探讨裴晓华教授治疗非哺乳期乳腺炎的用药规律。方法收集2021年4月至2023年12月裴晓华教授于北京中医药大学东直门医院厦门医院国际门诊部看诊非哺乳期乳腺炎患者的病历。采用Excel 2019描述药物频次、性味、归经。采用R studio 4.3.3软件分析关联规则、聚类,比较月经异常组、未诉月经异常组处方间Jaccard系数、组内φ系数,并进行可视化。结果本研究共发现1020首处方涉及226味中药,总频次为14765次,高频药物有甘草、当归、川芎等;药性以温、寒、平为主,药味以苦、甘、辛为主,归经以肝、脾、肺经最多。关联规则分析显示,黄芪-川芎-白芷-当归关联密切,药对川芎-当归参与构成药物组合最多。聚类分析得到6类药对或新方。组间比较发现,92.36%的Jaccard系数<0.5,炒麦芽-焦山楂、醋乳香-醋没药为特殊药对。结论裴晓华教授治疗非哺乳期乳腺炎组方规律为重视内调外透,善调女子冲任气血,对临床治疗和传承有重要意义。
基金National Key R&D Plan:Development of International Standards for Traditional Chinese Medicine Technology(No.2019YFC1712003)。
文摘Chinese medicated bath is one of the external therapies in Traditional Chinese Medicine(TCM),which has been widely used clinically.The“International Standard of Traditional Chinese Medicine Techniques:The Operating Specifications for Chinese Medicated Bath”is drawn up by the Beijing University of Chinese Medicine Third Affiliated Hospital and Beijing University of Chinese Medicine Xiamen Hospital in collaboration with domestic TCM universities and hospitals.The specification includes definition,operating process,points for attention and contraindications.It is targeted to provide reference for TCM providers at home and abroad with TCM background in clinical decision-making.
