The magnetic properties and textures of grain oriented silicon steel with different thickness rolled by cross shear rolling （CSR） of different mismatched speed ratio （MSR） and annealed in magnetic field under hyd...The magnetic properties and textures of grain oriented silicon steel with different thickness rolled by cross shear rolling （CSR） of different mismatched speed ratio （MSR） and annealed in magnetic field under hydrogen were presented.Effects of the factors such as thickness and mismatched speed ratio on the magnetic properties and recrystallization texture were analyzed and the recrystallization principles in magnetic field annealing were discussed. The study would provide a new route for mass production of high quality ultra-thin grain oriented silicon steel strip.展开更多
A positive biodiversity-ecosystem functioning(BEF)relationship is frequently reported for biotic communities with low diversity levels.However,whether this is also true for highly diverse soil microbial communities re...A positive biodiversity-ecosystem functioning(BEF)relationship is frequently reported for biotic communities with low diversity levels.However,whether this is also true for highly diverse soil microbial communities remains unclear.The study explored the BEF relationships between species richness and nitrogen(N)-transforming capability of nirK-and nirS-nitrite reducers,nitrous oxide reducers,and nitrite oxidizer communities in soils from five different vegetation types.The results consistently indicated negative BEF patterns in these N-transforming microbes.The relative abundance of keystone taxa from co-occurrence networks increased substantially with species richness but was negatively correlated with functional performance.Network complexity decreased in communities with high species richness.These findings suggest that negative selection and biotic competition may simultaneously generate negative BEF patterns.A conceptual model was also proposed in which the BEF relationship followed a quadratic curve that varied with the level of diversity.Microbial diversity is crucial for maintaining the balance of ecological systems because microorganisms play key roles in nutrient cycling and other essential biogeochemical processes.Recent studies have shown that increased diversity may not always lead to improved ecosystem function.The current study indicated that function decreased with species richness in soil Ntransforming bacterial communities.Keystone taxa were positively correlated with species richness but negatively correlated with function.Community complexity decreased with increasing species richness.These findings suggest that both negative selection effects and biotic competition may simultaneously generate negative biodiversity-ecosystem functional relationships.展开更多
Background and Aims:Cirrhotic cardiomyopathy(CCM)is a significant complication of cirrhosis,but its progression and underlying mechanisms remain incompletely understood.This study aimed to investigate dynamic changes ...Background and Aims:Cirrhotic cardiomyopathy(CCM)is a significant complication of cirrhosis,but its progression and underlying mechanisms remain incompletely understood.This study aimed to investigate dynamic changes in cardiac function,pathology,inflammation,and mitochondrial damage in a mouse model of CCM,and to compare echocardiographic characteristics in patients with cirrhosis.Methods:Bile duct ligation was performed in male C57BL/6J mice to induce cirrhosis.Longitudinal analyses were conducted over eight weeks.Cardiac function was assessed using serum biomarkers,echocardiography,and electrocardiography.Pathology was examined with hematoxylin and eosin,Masson’s trichrome,Sirius Red,and wheat germ agglutinin staining.Western blotting and immunohistochemistry were used to detect markers of inflammation,fibrosis,apoptosis,and mitochondrial function.Cardiac and liver function markers were also evaluated in patients with cirrhosis.Results:Mice subjected to bile duct ligation developed progressive cardiac dysfunction,including reduced cardiac output and diastolic dysfunction(enddiastolic interventricular septal thickness,left ventricular internal diameters,stroke volume,and left ventricular end-diastolic volume decreased,whereas ejection fraction and fractional shortening increased),as well as cardiac atrophy.Myocardial apoptosis,inflammation(elevated tumor necrosis factor,interleukin-6,and p65),and fibrosis worsened over time.Mitochondrial injury was characterized by reduced carnitine palmitoyltransferase 1A and peroxisome proliferator-activated receptor alpha,with increased hexokinase 2,pyruvate kinase M2,and lactate dehydrogenase A.In patients with cirrhosis,impaired cardiac function and elevated brain natriuretic peptide levels correlated with total bilirubin.Conclusions:The progression of CCM is closely associated with cirrhosis severity and appears to be driven by myocardial atrophy,apoptosis,inflammation,fibrosis,and mitochondrial dysfunction.展开更多
文摘The magnetic properties and textures of grain oriented silicon steel with different thickness rolled by cross shear rolling （CSR） of different mismatched speed ratio （MSR） and annealed in magnetic field under hydrogen were presented.Effects of the factors such as thickness and mismatched speed ratio on the magnetic properties and recrystallization texture were analyzed and the recrystallization principles in magnetic field annealing were discussed. The study would provide a new route for mass production of high quality ultra-thin grain oriented silicon steel strip.
基金supported by the Central Public-Interest Scientific Institution Basal Research Fund(Grant No.CAFYBB2019QB001)the National Key R&D Fund(Grant No.2023YFF130440302)the Natural Science Foundation of China(Grant No.31870099).
文摘A positive biodiversity-ecosystem functioning(BEF)relationship is frequently reported for biotic communities with low diversity levels.However,whether this is also true for highly diverse soil microbial communities remains unclear.The study explored the BEF relationships between species richness and nitrogen(N)-transforming capability of nirK-and nirS-nitrite reducers,nitrous oxide reducers,and nitrite oxidizer communities in soils from five different vegetation types.The results consistently indicated negative BEF patterns in these N-transforming microbes.The relative abundance of keystone taxa from co-occurrence networks increased substantially with species richness but was negatively correlated with functional performance.Network complexity decreased in communities with high species richness.These findings suggest that negative selection and biotic competition may simultaneously generate negative BEF patterns.A conceptual model was also proposed in which the BEF relationship followed a quadratic curve that varied with the level of diversity.Microbial diversity is crucial for maintaining the balance of ecological systems because microorganisms play key roles in nutrient cycling and other essential biogeochemical processes.Recent studies have shown that increased diversity may not always lead to improved ecosystem function.The current study indicated that function decreased with species richness in soil Ntransforming bacterial communities.Keystone taxa were positively correlated with species richness but negatively correlated with function.Community complexity decreased with increasing species richness.These findings suggest that both negative selection effects and biotic competition may simultaneously generate negative biodiversity-ecosystem functional relationships.
基金financially supported by grants from the National Natural Science Foundation of China(82174063,82204703)the National Natural Science Foundation of Anhui Province(2008085MH287)the Anhui Province Traditional Chinese Medicine Inheritance and Innovation Scientific Research Project(2020cczd03).
文摘Background and Aims:Cirrhotic cardiomyopathy(CCM)is a significant complication of cirrhosis,but its progression and underlying mechanisms remain incompletely understood.This study aimed to investigate dynamic changes in cardiac function,pathology,inflammation,and mitochondrial damage in a mouse model of CCM,and to compare echocardiographic characteristics in patients with cirrhosis.Methods:Bile duct ligation was performed in male C57BL/6J mice to induce cirrhosis.Longitudinal analyses were conducted over eight weeks.Cardiac function was assessed using serum biomarkers,echocardiography,and electrocardiography.Pathology was examined with hematoxylin and eosin,Masson’s trichrome,Sirius Red,and wheat germ agglutinin staining.Western blotting and immunohistochemistry were used to detect markers of inflammation,fibrosis,apoptosis,and mitochondrial function.Cardiac and liver function markers were also evaluated in patients with cirrhosis.Results:Mice subjected to bile duct ligation developed progressive cardiac dysfunction,including reduced cardiac output and diastolic dysfunction(enddiastolic interventricular septal thickness,left ventricular internal diameters,stroke volume,and left ventricular end-diastolic volume decreased,whereas ejection fraction and fractional shortening increased),as well as cardiac atrophy.Myocardial apoptosis,inflammation(elevated tumor necrosis factor,interleukin-6,and p65),and fibrosis worsened over time.Mitochondrial injury was characterized by reduced carnitine palmitoyltransferase 1A and peroxisome proliferator-activated receptor alpha,with increased hexokinase 2,pyruvate kinase M2,and lactate dehydrogenase A.In patients with cirrhosis,impaired cardiac function and elevated brain natriuretic peptide levels correlated with total bilirubin.Conclusions:The progression of CCM is closely associated with cirrhosis severity and appears to be driven by myocardial atrophy,apoptosis,inflammation,fibrosis,and mitochondrial dysfunction.
