Inflammation is important in the pathogenesis and development of cardiovascular diseases.Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through“the cholinergic anti-inf...Inflammation is important in the pathogenesis and development of cardiovascular diseases.Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through“the cholinergic anti-inflammatory pathway,”more specifically via theα7 nicotinic acetylcholine receptor(α7nAChR).In the current study,the role of the cholinergic anti-inflammatory pathway during septic shock,hypertension,and myocardial infarction is reviewed,and its possible clinical implications in cardiovascular diseases are discussed.展开更多
文摘Inflammation is important in the pathogenesis and development of cardiovascular diseases.Recent studies show that vagus nerve stimulation inhibits pro-inflammatory cytokine production through“the cholinergic anti-inflammatory pathway,”more specifically via theα7 nicotinic acetylcholine receptor(α7nAChR).In the current study,the role of the cholinergic anti-inflammatory pathway during septic shock,hypertension,and myocardial infarction is reviewed,and its possible clinical implications in cardiovascular diseases are discussed.
