Based on our previous studies of 3D-QSAR, 38 novel objective compounds belonging to 4 series were designed and successfully synthesized directed by the idea of reconstructing the structure of non-pharmacophores while ...Based on our previous studies of 3D-QSAR, 38 novel objective compounds belonging to 4 series were designed and successfully synthesized directed by the idea of reconstructing the structure of non-pharmacophores while reserving essential ones in triazoles. In vitro pilot studies on their antifungal activities showed that most compounds have inhibitory effects on C.albicans and some inhibit S.cerevisiae also. The effects on C.albicans of 5 compounds are more potent than or equal to that of fluconazole or itraconazole.展开更多
In this paper we research the lower bound of the eigenvalue of Spinc Dirac operator on the Spinc manifold. By the Weisenbock formula, we get an estimate of it, then following the idea of Th Friedrich [2] and X Zhang [...In this paper we research the lower bound of the eigenvalue of Spinc Dirac operator on the Spinc manifold. By the Weisenbock formula, we get an estimate of it, then following the idea of Th Friedrich [2] and X Zhang [6]. We get a finer estimate of it. As an application, we give a condition when the Seiberg-Witten equation only has 0 solution.展开更多
文摘Based on our previous studies of 3D-QSAR, 38 novel objective compounds belonging to 4 series were designed and successfully synthesized directed by the idea of reconstructing the structure of non-pharmacophores while reserving essential ones in triazoles. In vitro pilot studies on their antifungal activities showed that most compounds have inhibitory effects on C.albicans and some inhibit S.cerevisiae also. The effects on C.albicans of 5 compounds are more potent than or equal to that of fluconazole or itraconazole.
基金Supported in part by Mathematics Tianyuan Fund(10226002)
文摘In this paper we research the lower bound of the eigenvalue of Spinc Dirac operator on the Spinc manifold. By the Weisenbock formula, we get an estimate of it, then following the idea of Th Friedrich [2] and X Zhang [6]. We get a finer estimate of it. As an application, we give a condition when the Seiberg-Witten equation only has 0 solution.
