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Tau's function and dysfunction in the brain:when small changes have big consequences
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作者 Miguel Portillo debra toiber 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第1期152-153,共2页
With the increase of life expectancy and population growth,neurodegenerative diseases have risen too and are projected to be a major health public concern by 2050.Neurodegenerative diseases are characterized by the pr... With the increase of life expectancy and population growth,neurodegenerative diseases have risen too and are projected to be a major health public concern by 2050.Neurodegenerative diseases are characterized by the progressive decline of cognitive function leading to the subsequent loss of autonomy.Although the underlying causes of neurodegeneration are not well understood,aging is the main risk factor. 展开更多
关键词 DISEASES consequences FUNCTION
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DNA damage and neurodegeneration:the unusual suspect
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作者 Daniel Stein debra toiber 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第9期1441-1442,共2页
Neurodegenerative diseases are caused by the loss of neuro- nal cells. As neurons deteriorate, a patient may experience relatively mild symptoms such as failing to name objects and people. However, with the progressio... Neurodegenerative diseases are caused by the loss of neuro- nal cells. As neurons deteriorate, a patient may experience relatively mild symptoms such as failing to name objects and people. However, with the progression of the disease, symp- toms worsen resulting in loss of independence and a sense of"loss of oneself". Finally, the patient dies from a variety of complications. 展开更多
关键词 DNA damage and neurodegeneration:the unusual suspect
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