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Dynamic response of the ground beneath a high-speed railway based on typical upper Shanghai clays involving water table change
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作者 Jing HU Chengming YE +3 位作者 Juntao JIANG Shujing WU david thompson Xuecheng BIAN 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 2025年第8期787-800,共14页
A rising water table increases soil water content,reduces soil strength,and amplifies vibrations under identical train loads,thereby posing greater risks to train operations.To investigate this phenomenon,we used a 2.... A rising water table increases soil water content,reduces soil strength,and amplifies vibrations under identical train loads,thereby posing greater risks to train operations.To investigate this phenomenon,we used a 2.5D finite element(FE)model of a coupled vehicle–embankment–ground system based on Biot’s theory.The ground properties were derived from a typical soil profile of the Yangtze River basin,using geological data from Shanghai,China.The findings indicate that a rise in the water table leads to increased dynamic displacements of both the track and the ground.This amplification effect extends beyond the depth of the water table,impacting the entire embankment–foundation cross-section,and intensifies with higher train speeds.However,the water table rise has a limited impact on the critical speed of trains and dominant frequency contents.The dynamic response of the embankment is more significantly affected by water table rises within the subgrade than by those within the ground.When the water table rises into the subgrade,significant excess pore pressure is generated inside the embankment,causing a substantial drop in effective stress.As a result,the stress path of the soil elements in the subgrade approaches the Mohr-Coulomb failure line,increasing the likelihood of soil failure. 展开更多
关键词 Dynamic response Excess pore pressures Water table rise High-speed train 2.5D finite element(FE)model
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Methods for separating the noise produced by the wheels and track during a train pass‑by
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作者 david thompson Dong Zhao +4 位作者 Giacomo Squicciarini Martin Toward Ester Cierco Erwin Jansen Michael Dittrich 《Railway Engineering Science》 2025年第3期342-358,共17页
Rolling noise is produced by vibration of the wheels and track,induced by their combined surface roughness.It is important to know the relative contributions of the different sources,as this affects noise control stra... Rolling noise is produced by vibration of the wheels and track,induced by their combined surface roughness.It is important to know the relative contributions of the different sources,as this affects noise control strategies as well as acceptance testing of new rolling stock.Three different techniques are described that aim to use pass-by measurements to separate the wheel and track components of rolling noise.One is based on the TWINS model,which is tuned to measured track vibration.The second is based on the advanced transfer path analysis method,which provides an entirely experimental assessment.The third is based on the pass-by analysis method in combination with static vibroacoustic transfer functions which are obtained using a reciprocity method.The development of these methods is described and comparisons between them are presented using the results from three experimental measurement campaigns.These covered a metro train,a regional train and a high-speed train at a range of speeds.The various methods agree reasonably well in terms of overall trends,with moderate agreement in the mid-frequency region,and less consistent results at low and high frequency. 展开更多
关键词 Railway noise Rolling noise Source separation Pass-by tests
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Simplified prediction models for acoustic installation effects of train-mounted equipment
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作者 david thompson Dong Zhao Giacomo Squicciarini 《Railway Engineering Science》 EI 2024年第2期125-143,共19页
Acoustic models of railway vehicles in standstill and pass-by conditions can be used as part of a virtual certification process for new trains.For each piece of auxiliary equipment,the sound power measured on a test b... Acoustic models of railway vehicles in standstill and pass-by conditions can be used as part of a virtual certification process for new trains.For each piece of auxiliary equipment,the sound power measured on a test bench is combined with meas-ured or predicted transfer functions.It is important,however,to allow for installation effects due to shielding by fairings or the train body.In the current work,fast-running analytical models are developed to determine these installation effects.The model for roof-mounted sources takes account of diffraction at the corner of the train body or fairing,using a barrier model.For equipment mounted under the train,the acoustic propagation from the sides of the source is based on free-field Green’s functions.The bottom surfaces are assumed to radiate initially into a cavity under the train,which is modelled with a simple diffuse field approach.The sound emitted from the gaps at the side of the cavity is then assumed to propagate to the receivers according to free-field Green’s functions.Results show good agreement with a 2.5D boundary element model and with measurements.Modelling uncertainty and parametric uncertainty are evaluated.The largest variability occurs due to the height and impedance of the ground,especially for a low receiver.This leads to standard deviations of up to 4 dB at low frequencies.For the roof-mounted sources,uncertainty over the location of the corner used in the equivalent barrier model can also lead to large standard deviations. 展开更多
关键词 Train noise Auxiliary equipment Acoustic installation effects Virtual certification UNCERTAINTY
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Effect of cavity flow control on high-speed train pantograph and roof aerodynamic noise 被引量:12
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作者 Hogun Kim Zhiwei Hu david thompson 《Railway Engineering Science》 2020年第1期54-74,共21页
The pantograph and its recess on the train roof are major aerodynamic noise sources on high-speed trains.Reducing this noise is particularly important because conventional noise barriers usually do not shield the pant... The pantograph and its recess on the train roof are major aerodynamic noise sources on high-speed trains.Reducing this noise is particularly important because conventional noise barriers usually do not shield the pantograph.However,less attention has been paid to the pantograph recess compared with the pantograph.In this paper,the flow features and noise contribution of two types of noise reduction treatments rounded and chamfered edges are studied for a simplified high-speed train pantograph recess,which is represented as a rectangular cavity and numerically investigated at 1/10 scale.Improved delayed detached-eddy simulations are performed for the near-field turbulent flow simulation,and the Ffowcs Williams and Hawkings aeroacoustic analogy is used for far-field noise prediction.The highly unsteady flow over the cavity is significantly reduced by the cavity edge modifications,and consequently,the noise radiated from the cavity is reduced.Furthermore,effects of the rounded cavity edges on the flow and noise of the pantographs(one raised and one folded)are investigated by comparing the flow features and noise contributions from the cases with and without rounding of the cavity edges.Different train running directions are also considered.Flow analysis shows that the highly unsteady flow within the cavity is reduced by rounding the cavity edges and a slightly lower flow speed occurs around the upper parts of the raised pantograph,whereas the flow velocity in the cavity is slightly increased by the rounding.Higher pressure fluctuations occur on the folded pantograph and the lower parts of the raised pantograph,whereas weaker fluctuations are found on the panhead of the raised pantograph.This study shows that by rounding the cavity edges,a reduction in radiated noise at the side and the top receiver positions can be achieved.Noise reductions in the other directions can also be found. 展开更多
关键词 High-speed TRAIN Aeroacoustics PANTOGRAPH PANTOGRAPH RECESS CAVITY flow Noise CONTROL
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LC-MS/MS analysis of 2-aminothiazoline-4-carboxylic acid as a forensic biomarker for cyanide poisoning 被引量:2
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作者 Jorn CC Yu Sarah Martin +3 位作者 Jessica Nasr Katelyn Stafford david thompson Ilona Petrikovics 《World Journal of Methodology》 2012年第5期33-41,共9页
AIM: To demonstrate the potential of using 2-aminothiazoline-4-carboxylic acid(ATCA) as a novel biomarker/forensic biomarker for cyanide poisoning. METHODS: A sensitive method was developed and employed for the identi... AIM: To demonstrate the potential of using 2-aminothiazoline-4-carboxylic acid(ATCA) as a novel biomarker/forensic biomarker for cyanide poisoning. METHODS: A sensitive method was developed and employed for the identification and quantification of ATCA in biological samples, where the sample extraction and clean up were achieved by solid phase extraction(SPE). After optimization of SPE procedures, ATCA was analyzed by high performance liquid chromatographytandem mass spectrometry. ATCA levels following the administration of different doses of potassium cyanide(KCN) to mice were measured and compared to endogenous ATCA levels in order to study the significance of using ATCA as a biomarker for cyanide poisoning.RESULTS: A custom made analytical method was established for a new(mice) model when animals were exposed to increasing KCN doses. The application of this method provided important new information on ATCA as a potential cyanide biomarker. ATCA concentration in mice plasma samples were increased from 189 ± 28 ng/mL(n = 3) to 413 ± 66 ng/mL(n = 3) following a 10 mg/kg body weight dose of KCN introduced subcutaneously. The sensitivity of this analytical method proved to be a tool for measuring endogenous level of ATCA in mice organs as follows: 1.2 ± 0.1 μg/g for kidney samples, 1.6 ± 0.1 μg/g for brain samples, 1.8 ± 0.2 μg/g for lung samples, 2.9 ± 0.1 μg/g for heart samples, and 3.6 ± 0.9 μg/g for liver samples. CONCLUSION: This finding suggests that ATCA has the potential to serve as a plasma biomarker / forensic biomarker for cyanide poisoning. 展开更多
关键词 Forensic science BIOMARKER Cyanide poisoning 2-aminothiazoline-4-carboxylic acid LC-MS/MS
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药物经济学研究结果的本土化:方法学挑战及潜在的解决方法 被引量:1
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作者 Amy O' Sullivan david thompson 汤涵 《中国药物经济学》 2009年第1期81-83,共3页
世界医药市场主要集中在北美、欧洲以及亚太地区,这些地区长期以来一直在开展药物经济学研究。随着研究工作的扩大,在一个国家所开展的严格的科学研究的成果,有可能直接被其他国家应用。本文主要讨论将一国药物经济学研究成果为另外... 世界医药市场主要集中在北美、欧洲以及亚太地区,这些地区长期以来一直在开展药物经济学研究。随着研究工作的扩大,在一个国家所开展的严格的科学研究的成果,有可能直接被其他国家应用。本文主要讨论将一国药物经济学研究成果为另外一个具有不同族群、不同制度、不同卫生筹资特征的国家应用时,可能会面临的方法学挑战以及解决方法。 展开更多
关键词 药物经济学 方法学 本土化 世界医药市场 亚太地区 科学研究 卫生筹资
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Gosport须成为改变医疗卫生行业等级制度的转折点
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作者 Philip Darbyshire david thompson +2 位作者 沈玄韬(翻译) 张瑞明(翻译) 翁建平(校) 《中国医院院长》 2020年第1期19-20,共2页
Gosport报告独立调查了上世纪90年代戈斯波特战争纪念医院(Gosport War Memorial Hospital)大约600名患者的死亡情况,它给每一位医疗专业领域的人员敲响了警钟。这份报告不应该被搁置和遗忘,受这个事件影响的家庭应该得到更多关注。
关键词 医疗卫生行业 医疗专业 纪念医院 等级制度 转折点
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从治理角度看法规遵从
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作者 david thompson 程洁 《中国计算机用户》 2007年第3期46-46,共1页
关键词 IT治理 法规 企业
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心肌梗死患者院外自助式心脏康复的效果研究 被引量:33
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作者 高丽 李峥 +1 位作者 david Arthur david thompson 《中华护理杂志》 CSCD 北大核心 2008年第5期392-396,共5页
目的本研究旨在观察急性心肌梗死患者进行院外自助式心脏康复的效果。方法便利选取136例首次发作的急性心肌梗死患者作为研究对象,随机分为两组,每组各68例。实验组在研究者督导下进行以运动锻炼、饮食控制、心理调适为主要内容的院外... 目的本研究旨在观察急性心肌梗死患者进行院外自助式心脏康复的效果。方法便利选取136例首次发作的急性心肌梗死患者作为研究对象,随机分为两组,每组各68例。实验组在研究者督导下进行以运动锻炼、饮食控制、心理调适为主要内容的院外自助式心脏康复;对照组只接受常规指导。分别在患者出院后3周、6周、12周时评价其康复效果。结果实验组患者较对照组而言,焦虑、抑郁和心理健康状况得到明显改善;某些不良生活方式,如吸烟和缺乏运动得到改善;胸部不适得到缓解;门诊就诊率和再入院率明显降低;但两组自尊状况和生活质量没有显著的差异。结论院外自助式心脏康复对于心肌梗死患者的心脏康复能够起到积极的作用。 展开更多
关键词 心肌梗死 康复护理 生活质量 病人再入院
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Numerical approach for the simulation of flow-induced noise around a structure with complex geometry: High-speed train bogie in a cavity
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作者 Yuan He david thompson Zhiwei Hu 《International Journal of Fluid Engineering》 2024年第3期29-45,共17页
The bogie region is a significant source of aerodynamic noise on high-speed trains. Owing to its complex geometry and flow field, numerical simulations using computational fluid dynamics are especially challenging. Th... The bogie region is a significant source of aerodynamic noise on high-speed trains. Owing to its complex geometry and flow field, numerical simulations using computational fluid dynamics are especially challenging. The main challenge is to achieve a grid with adequate resolution,especially in the boundary layer, while ensuring computational affordability. This challenge is addressed here by employing a hybrid grid,integrating a structured hexahedral mesh near solid surfaces with an unstructured polyhedral mesh in the remaining volume. To limit the number of cells in the boundary layer region, the delayed detached eddy simulation method is adopted. Additionally, to achieve a further reduction in the cell count, the Reynolds number of the model is decreased by scaling down the model size and lowering the inflow speed. The hybrid grid generation and numerical settings are guided by validated simulations of flow over cylinders. A grid sensitivity study, conducted with a simplified half-width bogie model, reveals the meshing requirements for the full-width model. Aerodynamic results highlight the rear section of the cavity and bogie as primary noise sources, emphasizing the critical role of the detached shear layer from upstream components.Time-resolved surface pressure data are input into the Ffowcs Williams–Hawkings equation for far-field noise calculation. The results indicate that the sound energy is concentrated below 200 Hz in the full-scale model, with the cavity contributing more than the bogie. This study provides a practical numerical approach for simulating a structure with complex geometry, offering insights for realistic model simulations. 展开更多
关键词 FLOW GEOMETRY noise
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Gosport必须成为改变医疗卫生行业等级制度的转折点
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作者 Philip Darbyshire david thompson +2 位作者 沈玄韬(译) 张瑞明(译) 翁建平(审校) 《英国医学杂志中文版》 2019年第10期598-600,共3页
"如果要杜绝类似Mid Staffordshire和Morecambe Bay的丑闻,所有医疗行业员工都应有权质疑各级同事的决策,并表达他们的担忧而不会受到任何报复",Philip Darbyshire和David Thompson写道。
关键词 医疗卫生行业 医疗行业 等级制度 转折点
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