Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough ...Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough tensile force to keep fibrotic defects larger than 5 mm approximated. Herein we present a case of successful endoscopic closure of a gastrocolic fistula in a severely malnourished patient with complex post-surgical upper GI anatomy. We strongly believe that this device is a major breakthrough for the management of various types of discontinuity defects or fistulas. In addition, we show the usefulness of placing a direct jejunostomy using the double balloon enteroscopy (DBE) technique during the same procedure. The concept of providing direct jejunal feedings while allowing for upper gas-trointestinal bowel rest to promote the healing of the minimally invasive endoscopic operation is novel. Thus, our case is unique and exemplifies the utility of mini-mally invasive endoscopic endoluminal surgery.展开更多
We report an ultrafast laser mode-locked with a graphene saturable absorber.The linear dispersions of the Dirac electrons in graphene enable wideband tunability.We get-1 ps pulses,tunable between 1525 and 1559 nm,with...We report an ultrafast laser mode-locked with a graphene saturable absorber.The linear dispersions of the Dirac electrons in graphene enable wideband tunability.We get-1 ps pulses,tunable between 1525 and 1559 nm,with stable mode-locking,insensitive to environmental perturbations.展开更多
We report bound states of solitons from a harmonic mode-locked fiber laser based on a solution-processed graphene saturable absorber. Stable soliton pairs, 26.2 ps apart, are generated with 720 fs duration. By simply ...We report bound states of solitons from a harmonic mode-locked fiber laser based on a solution-processed graphene saturable absorber. Stable soliton pairs, 26.2 ps apart, are generated with 720 fs duration. By simply increasing the pump power, the laser can also generate harmonic mode-locking with harmonics up to the26 th order(409.6 MHz repetition rate). This is a simple, low-cost, all-fiber, versatile multifunction ultrafast laser that could be used for many applications.展开更多
文摘Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough tensile force to keep fibrotic defects larger than 5 mm approximated. Herein we present a case of successful endoscopic closure of a gastrocolic fistula in a severely malnourished patient with complex post-surgical upper GI anatomy. We strongly believe that this device is a major breakthrough for the management of various types of discontinuity defects or fistulas. In addition, we show the usefulness of placing a direct jejunostomy using the double balloon enteroscopy (DBE) technique during the same procedure. The concept of providing direct jejunal feedings while allowing for upper gas-trointestinal bowel rest to promote the healing of the minimally invasive endoscopic operation is novel. Thus, our case is unique and exemplifies the utility of mini-mally invasive endoscopic endoluminal surgery.
基金We acknowledge funding from a Royal Society Brian Mercer Award for Innovation,the European Research Council(ERC)grant NANOPOTS,Engineering and Physical Sciences Research Council(EPSRC)grants(Nos.EP/GO30480/1 and EP/G042357/1),King’s College and Imperial College.
文摘We report an ultrafast laser mode-locked with a graphene saturable absorber.The linear dispersions of the Dirac electrons in graphene enable wideband tunability.We get-1 ps pulses,tunable between 1525 and 1559 nm,with stable mode-locking,insensitive to environmental perturbations.
基金National Natural Science Foundation of China(NSFC)(61575106)Beihang University(BUAA)+1 种基金Beijing Advanced Innovation Center for Big Data-Based Precision Medicine(Ultrafast Pulsed Fiber Lasers and Applications)School of Instrumentation and Optoelectronic Engineering
文摘We report bound states of solitons from a harmonic mode-locked fiber laser based on a solution-processed graphene saturable absorber. Stable soliton pairs, 26.2 ps apart, are generated with 720 fs duration. By simply increasing the pump power, the laser can also generate harmonic mode-locking with harmonics up to the26 th order(409.6 MHz repetition rate). This is a simple, low-cost, all-fiber, versatile multifunction ultrafast laser that could be used for many applications.
