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Impact of climate simulation resolutions on future energy system reliability assessment:A Texas case study
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作者 Xiangtian Zheng Le Xie +3 位作者 Kiyeob Lee dan fu Jiahan Wu Ping Chang 《iEnergy》 2023年第3期222-230,共9页
The reliability of energy systems is strongly influenced by the prevailing climate conditions.With the increasing prevalence of renewable energy sources,the interdependence between energy and climate systems has becom... The reliability of energy systems is strongly influenced by the prevailing climate conditions.With the increasing prevalence of renewable energy sources,the interdependence between energy and climate systems has become even stronger.This study examines the impact of different spatial resolutions in climate modeling on energy grid reliability assessment,with the Texas interconnection between 2033 and 2043 serving as a pilot case study.Our preliminary findings indicate that while low-resolution climate simulations can provide a rough estimate of system reliability,high-resolution simulations can provide more informative assessment of low-adequacy extreme events.Furthermore,both high-and low-resolution assessments suggest the need to prepare for severe blackout events in winter due to extremely low temperatures. 展开更多
关键词 High-resolution climate model power system reliability resource adequacy
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Magnesium isoglycyrrhizinate ameliorates isoproterenol-induced myocardial remodeling in mice by regulating oxidative stress and apoptosis via the PI3K/AKT1 signaling pathway 被引量:2
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作者 Xingyu Zhou dan fu +8 位作者 Saige Sun Qiuyan Liu Longxing Liu Jia Shi Zijie Ge Yu Ma Yilin He Li Xu Kai Qian 《Journal of Chinese Pharmaceutical Sciences》 2025年第4期321-333,共13页
The aim of this study is to investigate the mechanism of magnesium isoglycyrrhizinate(MgIG)in the treatment of myocardial remodeling induced by isoproterenol(ISO)in mice.We assessed the impact of MgIG on ISO-induced m... The aim of this study is to investigate the mechanism of magnesium isoglycyrrhizinate(MgIG)in the treatment of myocardial remodeling induced by isoproterenol(ISO)in mice.We assessed the impact of MgIG on ISO-induced myocardial remodeling by activating the PI3K/AKT1 pathway.The cardiac function of mice was evaluated by echocardiography,revealing that MgIG could improve left ventricular function.Pathological staining analysis showed that MgIG could reduce the degree of myocardial injury caused by ISO.Serum data detected by ELISA demonstrated that MgIG could decrease the levels of CK-MB,MDA,and LDH while increasing the activity of GSH-Px.Western blotting analysis revealed that protein expression levels of Collagen I,BNP,Bax,cleaved caspase-3,p-PI3K,and p-AKT1 were decreased,whereas the protein expressions of Bcl-2,COX2,and SOD1 were increased upon MgIG treatment.However,the activation of the PI3K pathway reversed the cardioprotective effects of MgIG,as evidenced by the addition of PI3K activators.Taken together,our comprehensive results suggested that MgIG could improve ISO-induced myocardial remodeling,potentially through its mechanism of inhibiting the PI3K/AKT1 pathway to regulate apoptosis and oxidative stress. 展开更多
关键词 Magnesium isoglycyrrhizinate ISOPROTERENOL Myocardial remodeling PI3K/AKT1 APOPTOSIS Oxidative stress
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Analysis of Emissions Profiles of Hydraulic Fracturing Engine Technologies
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作者 William Nieuwenburg Andrew C. Nix +3 位作者 dan fu Tony Yeung Warren Zemlak Nick Wells 《Energy and Power Engineering》 CAS 2023年第1期1-34,共36页
Today, the oil and gas industry, and in particular hydraulic fracturing operations, have come under increasing pressure from regulators and the public to reduce emissions. As the industry evolves, oil and gas producer... Today, the oil and gas industry, and in particular hydraulic fracturing operations, have come under increasing pressure from regulators and the public to reduce emissions. As the industry evolves, oil and gas producers are in the position of evaluating alternative technologies which will support their objectives of reducing their overall emissions profile and carbon footprint. As a response, the deployment of technology and solutions to reduce emissions related to hydraulic fracturing applications has recently accelerated, creating various options to address these industry challenges. BJ Energy Solutions and West Virginia University have been working on the application and emissions characterization of various hydraulic fracturing technologies. A study was conducted to evaluate the efficiency and resultant emissions from various technologies, including natural gas reciprocating engines, diesel-natural gas dual-fuel engines, large (>24 MW) gas turbines, and direct drive turbines. The study involved the development of an emissions model with the purpose of estimating total emissions of carbon dioxide (CO<sub>2</sub>), nitrous oxide (N2O) and exhaust methane (CH<sub>4</sub>) slip, all Greenhouse Gases (GHGs), and converted to tons of CO<sub>2</sub> equivalent emissions per day of operation. The model inputs are the required Hydraulic Horsepower (HHP) based on pumping rate and pressure for various shale play scenarios. The model calculates emissions from the TITAN, which is a direct-drive turbine model fielded by BJ, using data collected following U.S. Environmental Protection Agency (EPA) testing protocols. The model also calculates and compares other hydraulic fracturing technologies utilizing published Original Equipment Manufacturer (OEM) data. Relevant EPA-regulated criteria emissions of oxides of nitrogen (NO<sub>x</sub>), Carbon Monoxide (CO) and Particulate Matter (PM) are also reported. Modeling results demonstrated that in most cases, the TITAN gas turbine system has lower total GHG emissions than conventional diesel and other next-generation technologies, and also has lower criteria emissions. The benefits of the TITAN gas turbine system compared to the other technologies stems from significantly lower methane slip, and the high-power transfer efficiency resulting from directly connecting a turbine to a reciprocating pump, despite the comparatively lower thermal efficiency. 展开更多
关键词 Hydraulic Fracturing Greenhouse Gas Emissions Gas Turbines Natural Gas Engines Engine Efficiency EPA-Regulated Emissions
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Objective optical quality and visual outcomes after the PresbyMAX monocular ablation profile 被引量:9
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作者 dan fu Jing Zhao Xing-Tao Zhou 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2020年第7期1060-1065,共6页
AIM:To assess objective visual quality after presbyopia correction using the Presby MAX monocular mode.METHODS:This prospective,nonrandomized study included 28 eyes from 18 patients(mean age 50.4±5.6 y)who underw... AIM:To assess objective visual quality after presbyopia correction using the Presby MAX monocular mode.METHODS:This prospective,nonrandomized study included 28 eyes from 18 patients(mean age 50.4±5.6 y)who underwent presbyopia correction with the Presby MAX monocular mode.Monocular and binocular visual acuities were evaluated preoperatively,1 d,1 wk,1,3 mo,and 1 y after surgery.Optical quality was analyzed by HartmannShack wavefront aberration supported cornea ablation.Modulation transfer function(MTF)cutoff frequency,Strehl ratio,and objective scattering index(OSI)were analyzed using an optical quality analysis system.RESULTS:One year after surgery,100%and 94.4%of patients achieved binocular uncorrected distance and near visual acuity of 20/25,respectively.At the last visit Spherical aberration and total higher aberration were higher than the corresponding preoperative levels(P<0.001);however,no significant difference was found in MTF,OSI,or Strehl ratio.Transient decreases in OSI and MTF mainly occurred in the nondominant eyes.There was no significant difference in optical quality between the dominant and nondominant eyes,except for spherical aberration and horizontal coma(P<0.05).CONCLUSION:The Presby MAX monocular mode is safe and effective for presbyopia correction.It has little effect on optical quality,though short-term degraded optical quality occurred mainly in the bi-aspheric ablated eyes. 展开更多
关键词 PRESBYOPIA MONOVISION optical quality PresbyMAX
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Refractive outcomes and optical quality of PRESBYOND laser-blended vision for presbyopia correction 被引量:5
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作者 dan fu Aruma Aruma +3 位作者 Ye Xu Tian Han Fei Xia Xing-Tao Zhou 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第10期1671-1675,共5页
AIM: To investigate the one-year refractive outcomes and optical quality following PRESBYOND laser-blended vision(LBV).METHODS: This retrospective study included 20 patients who underwent PRESBYOND treatment between J... AIM: To investigate the one-year refractive outcomes and optical quality following PRESBYOND laser-blended vision(LBV).METHODS: This retrospective study included 20 patients who underwent PRESBYOND treatment between Jan 2019 and Aug 2020. The patients were asked to attend a followup outpatient visit one year after surgery. Distance and near visual acuity as well as subjective refraction were examined. Optical quality was assessed using wavefront-supported custom ablation. A questionnaire evaluating optical quality and satisfaction was completed at the last visit.RESULTS: The average patient age was 48.1±7.4 y(range, 41 to 58 y). The mean preoperative spherical equivalent was-7.59±2.39D. At the one-year follow-up, two eyes(both dominant eyes) lost one line of corrected distance visual acuity(CDVA), while the remaining eyes(38/40) maintained or gained lines of CDVA. The average binocular uncorrected distance visual acuity improved from 0.15±0.03 to 0.90±0.26(decimal vision;P<0.001). The average binocular uncorrected near visual acuity increased from 0.34±0.28 to 0.97±0.07(P<0.001). The spherical aberration was 0.04±0.06 μm in the nondominant eye and 0.09±0.09 μm in the dominant eye(P=0.02). All patients were satisfied with or accepted the outcomes of the surgery. The primary complaints were related to disturbances in night vision and relatively inferior near vision.CONCLUSION: Over the one-year observation period, PRESBYOND is a safe and effective option for presbyopia correction. The optical quality and near vision deserve further investigation. 展开更多
关键词 PRESBYOND laser-blended vision PRESBYOPIA optical quality
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Cap morphology after small-incision lenticule extraction and its effects on intraocular scattering 被引量:2
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作者 dan fu Lin Wang +1 位作者 Xing-Tao Zhou Zhi-Qiang Yu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第3期456-461,共6页
AIM: To investigate cap morphology after small-incision lenticule extraction (SMILE) and its effects on intraocular scattering. METHODS: Sixty-five eyes of 33 patients undergoing SMILE were enrolled. In addition ... AIM: To investigate cap morphology after small-incision lenticule extraction (SMILE) and its effects on intraocular scattering. METHODS: Sixty-five eyes of 33 patients undergoing SMILE were enrolled. In addition to regular evaluation, Fourier-domain optical coherence tomography was used to investigate cap thickness at ld, lwk, 1 and 3mo postoperatively. The optical quality including modulation transfer function cutoff frequency, Strehl ratio, Optical Quality Analysis System (OQAS) values, and objective scattering index (OSI), were evaluated using OQASTM. RESULTS: Cap thickness decreased from ld to lwk (P〈0.001), but remained higher than intended thickness of 120 μm after 3mo (P〈0.001). Cap thickness in central area was thinner than that of in the paracentral and peripheral areas (P〈0.0001). Total number of microdistortions decreased from ld to 3mo (P〈0.0001). Pearson analysis revealed a weak correlation between OSI and standard deviation of cap thickness at ld and lmo, as well as between range of cap thickness and OSI at 1mo. No correlation was found between microdistortion and OSI, but a negative correlation existed between microdistortion and range at ld and lmoafter surgery. CONCLUSION: The corneal cap tends to be more accurate and regular with time lapse. Better cap morphology tends to contribute less intraocular scattering in the eyes undergoing SMILE. 展开更多
关键词 corneal cap intraocular scattering microdis-tortion small-incision lenticule extraction
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Distinct structural characteristics define a new subfamily of Mycoplasma ferritin 被引量:1
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作者 Wenming Wang Xiaojia Liu +5 位作者 Yajie Wang Yuan Wang dan fu Hongfang Xi Yi Zhao Hongfei Wang 《Chinese Chemical Letters》 SCIE CAS CSCD 2022年第11期4952-4955,共4页
Ferritins can generally be divided into four subfamilies based on their structural characteristics,namely,the classic ferritins(Ftns),bacterioferritins(Bfrs),DNA-binding proteins from starved cells(Dps’),and encapsul... Ferritins can generally be divided into four subfamilies based on their structural characteristics,namely,the classic ferritins(Ftns),bacterioferritins(Bfrs),DNA-binding proteins from starved cells(Dps’),and encapsulated ferritins(Enc Ftns).However,the ferritin from Mycoplasma penetrans(Mpef)possesses a particular ferroxidase center with an extreme low activity and exhibits unusual characteristics,indicating that it could be a member of a quite different subfamily of ferritins.Hereby,the crystal structure of the ferritin from Ureaplasma urealyticum(Uurf)is presented,Mpef and Uurf have very similar properties,though they display very low sequence similarity.Thus,ferritins from Mycoplasma with these unique properties do not belong to any known subfamily,but they should rather be placed in a novel ferritin subfamily,which we term Mycoplasma Ferritin(Mfr). 展开更多
关键词 FERRITIN Ferritin subfamily UREAPLASMA MYCOPLASMA Crystal structure
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An Analysis on Mental Health Education of College Students with Financial Difficulties 被引量:1
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作者 Shuzhen WANG Ling NI +2 位作者 Chaoqiong LI Rui LANG dan fu 《Asian Agricultural Research》 2017年第6期108-109,共2页
With the enrollment expansion of college and continuous reform of college education system and college charging system,the number of college students with financial difficulties is increasing. The college students wit... With the enrollment expansion of college and continuous reform of college education system and college charging system,the number of college students with financial difficulties is increasing. The college students with family financial difficulties not only bear the huge economic burden,but also bear the huge pressure of learning and mental stress,and they have many kinds of psychological problems including psychological distress of tension and anxiety,psychological conflict of self-respect and self-abasement,conflict of desire for interpersonal interaction and self-containment and strong vanity and dependence mentality. This paper puts forward the corresponding recommendations to solve these problems. 展开更多
关键词 COLLEGE Students with financial difficulties Psychological problems Mental health education
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Using data-limited approaches to assess data-rich Indian Ocean bigeye tuna:Data quantity evaluation and critical information for management implications
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作者 Ya'nan Li Jiangfeng Zhu +2 位作者 Xiaojie Dai dan fu Yong Chen 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2022年第3期11-23,共13页
The majority of fishery stocks in the world are data limited,which limits formal stock assessments.Identifying the impacts of input data on stock assessment is critical for improving stock assessment and developing pr... The majority of fishery stocks in the world are data limited,which limits formal stock assessments.Identifying the impacts of input data on stock assessment is critical for improving stock assessment and developing precautionary management strategies.We compare catch advice obtained from applications of various datalimited methods(DLMs)with forecasted catch advice from existing data-rich stock assessment models for the Indian Ocean bigeye tuna(Thunnus obesus).Our goal was to evaluate the consistency of catch advice derived from data-rich methods and data-limited approaches when only a subset of data is available.The Stock Synthesis(SS)results were treated as benchmarks for comparison because they reflect the most comprehensive and best possible scientific information of the stock.This study indicated that although the DLMs examined appeared robust for the Indian Ocean bigeye tuna,the implied catch advice differed between data-limited approaches and the current assessment,due to different data inputs and model assumptions.Most DLMs tended to provide more optimistic catch advice compared with the SS,which was mostly influenced by historical catches,current abundance and depletion estimates,and natural mortality,but was less sensitive to life-history parameters(particularly those related to growth).This study highlights the utility of DLMs and their implications on catch advice for the management of tuna stocks. 展开更多
关键词 stock assessment bigeye tuna data-limited fisheries management Indian Ocean
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An Empirical Analysis on Mental Health of Agricultural College Students
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作者 dan fu Ning MA Shuzhen WANG 《Asian Agricultural Research》 2017年第6期110-112,共3页
Based on the empirical survey of 2013-2016 college students in Northwest A&F University,we analyze the 9260 valid samples,and the survey involves emotional state,self-worth,psychological adjustment capacity and st... Based on the empirical survey of 2013-2016 college students in Northwest A&F University,we analyze the 9260 valid samples,and the survey involves emotional state,self-worth,psychological adjustment capacity and students’ attitude towards mental health education.On the basis of statistical data,we summarize the general situation of agricultural college students’ mental health,analyze the problems in agricultural college students’ psychological development and bring forward the feasible recommendations. 展开更多
关键词 College students Mental health Current situation RECOMMENDATIONS
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155例鎖骨骨折的手術治療
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作者 朱向輝 李衛平 +4 位作者 陳子傑 祁斌時 符丹 曾媛芳 何經緯 《镜湖医学》 2004年第1期25-27,共3页
目的分析本院10年來收治155例鎖骨骨折的手術治療情況。方法本院從1993年2月-2002年12月十年期間收治鎖骨骨折363例,其中155例採用手術治療;分析其療效。結果男:女=126:29;年齡9~78歲-19-40歲佔97例。左:右:雙側=63:89:3。其發病原因以... 目的分析本院10年來收治155例鎖骨骨折的手術治療情況。方法本院從1993年2月-2002年12月十年期間收治鎖骨骨折363例,其中155例採用手術治療;分析其療效。結果男:女=126:29;年齡9~78歲-19-40歲佔97例。左:右:雙側=63:89:3。其發病原因以直接碰傷爲主(108例)。其中交通傷(49例)爲主要損傷原因。新鮮骨折151例,陳舊骨折祗有4例。粉碎性骨折較多,有114例,單純骨折41例:骨折部位分成内:中:外(三段)爲0:145:9(次)。手術治療以克氏針内固定爲主(153例),其中118例加鋼絲結紮粉碎骨片。改進入釘方向,使保留在皮下的釘尾,留在鎖骨的胸骨端皮下,避免病人在側臥時碰撞留在鎖骨的肩胛骨端釘尾產生不舒服感覺。術後除一例感染外,其餘無感染,153例先後回院複查,均能骨性癒合,拆除内固定材料。未發現有不連接者。結論鎖骨骨折是一種常見的創傷性疾病,其發生的主要原因爲直接碰傷-以交通意外爲主。骨折好發在中1/3段。克氏針加鋼絲結紮粉碎骨片是首選的手術治療方法。 展开更多
关键词 鎖骨 骨折 手術治療
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Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding 被引量:4
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作者 dan fu Dongming Zhao +9 位作者 Wei Zhang Guangshun Zhang Mingyu Li Zheng Zhang Yuhui Wang Dongdong Sun Peng Jiao Cheng Chen Yu Guo Zihe Rao 《Protein & Cell》 SCIE CAS CSCD 2020年第8期606-612,共7页
Dear Editor, African swine fever (ASF) is a highly contagious disease of domestic pigs caused by African swine fever virus (ASFV),with mortality rates approaching 90%-100%.The first ASF case was described in 1921 in K... Dear Editor, African swine fever (ASF) is a highly contagious disease of domestic pigs caused by African swine fever virus (ASFV),with mortality rates approaching 90%-100%.The first ASF case was described in 1921 in Kenya.Over the past decades, ASF has spread from Sub-Saharan Africa to Europe and Asia, and pose a huge threat to global food safety.Since the first ASF case reported in August 2018, more than 10 million pigs had been culled in China at an enormous economic loss.The risk of ASFV mutating to infect humans is extremely low.However, ASF not only threatens food security but also severely strikes the world economy in many fields, such as the global supply of the blood thinner heparin,most of which is produced from pigs.Hence, ASF is a strictly monitored infectious animal disease by OIE (World Organization for Animal Health), unfortunately, there is no approved drug or vaccine against this lethal viral disease. 展开更多
关键词 SWINE FEVER AFRICAN
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Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly 被引量:4
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作者 Guobang Li dan fu +10 位作者 Guangshun Zhang Dongming Zhao Mingyu Li Xue Geng Dongdong Sun Yuhui Wang Cheng Chen Peng Jiao Lin Cao Yu Guo Zihe Rao 《Protein & Cell》 SCIE CAS CSCD 2020年第8期600-605,共6页
Dear Editor,The African swine fever(ASF)is a highly contagious hemorrhagic and lethal disease in domestic pigs.The ASF outbreaks of in many Asia countries,including China,Vietnam,Mongolia,and South Korea,have posed a ... Dear Editor,The African swine fever(ASF)is a highly contagious hemorrhagic and lethal disease in domestic pigs.The ASF outbreaks of in many Asia countries,including China,Vietnam,Mongolia,and South Korea,have posed a huge threat to the pig indusry.In the attempt to stop ASF from spreading further in China's Mainland,more than 10 million pigs have been culled since August 2018.The causative agent for ASF is a DNA virus,African swine fever virus(ASFV).Although this deadly disease has been reported in Kenya nearly one hundred years ago,there has been no vaccine for protection from ASFV infection or effective treatments to cure ASF until now. 展开更多
关键词 SWINE FEVER AFRICAN
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