Objective: to explore the value of ADC and relative ADC (rADC) in differentiating non lumpy mastitis from non lumpy invasive ductal carcinoma. Methods: 39 cases of breast lesions confirmed by pathology in Cangzhou Peo...Objective: to explore the value of ADC and relative ADC (rADC) in differentiating non lumpy mastitis from non lumpy invasive ductal carcinoma. Methods: 39 cases of breast lesions confirmed by pathology in Cangzhou Peoples Hospital from January 2015 to January 2021 were retrospectively analyzed, including 19 cases of non lumpy mastitis and 20 cases of non lumpy invasive ductal carcinoma. Use Philips ingenia 3.0T superconducting MR scanner to scan, measure the ADC value of the lesion area and its ipsilateral breast normal gland, and calculate the rADC value (lesion ADC value / ipsilateral breast normal gland ADC value). Do independent sample t-test for the ADC value of non lumpy mastitis group and non lumpy invasive ductal carcinoma group, non lumpy mastitis group rADC value and non lumpy invasive ductal carcinoma group rADC value respectively, and draw the ROC curve. Results: ADC value of non lumpy mastitis group was (1.32 ± 0.25) × 10-3mm2/s, ADC value of non mass invasive ductal carcinoma group (0.98 ± 0.13) × 10- 3mm2/s(t 5.179,P <0.001);RADC value in non lumpy mastitis group was 0.73 ± 0.18, and rADC value in non lumpy invasive ductal carcinoma group was 0.55 ± 0.11 (t 3.764, P < 0.001). The best diagnostic cut-off point of ADC value is 1.15 × 10-3mm2/s, the area under the ROC curve is 0.911, the sensitivity is 78.9%, the specificity is 95%, the best diagnostic dividing point of rADC value is 0.655, the area under the ROC curve is 0.791, the sensitivity is 68.4%, and the specificity is 90%. Conclusion: ADC value and rADC value can be used to distinguish non lumpy mastitis from non lumpy invasive ductal carcinoma, and the diagnostic accuracy of ADC value is higher.展开更多
文摘Objective: to explore the value of ADC and relative ADC (rADC) in differentiating non lumpy mastitis from non lumpy invasive ductal carcinoma. Methods: 39 cases of breast lesions confirmed by pathology in Cangzhou Peoples Hospital from January 2015 to January 2021 were retrospectively analyzed, including 19 cases of non lumpy mastitis and 20 cases of non lumpy invasive ductal carcinoma. Use Philips ingenia 3.0T superconducting MR scanner to scan, measure the ADC value of the lesion area and its ipsilateral breast normal gland, and calculate the rADC value (lesion ADC value / ipsilateral breast normal gland ADC value). Do independent sample t-test for the ADC value of non lumpy mastitis group and non lumpy invasive ductal carcinoma group, non lumpy mastitis group rADC value and non lumpy invasive ductal carcinoma group rADC value respectively, and draw the ROC curve. Results: ADC value of non lumpy mastitis group was (1.32 ± 0.25) × 10-3mm2/s, ADC value of non mass invasive ductal carcinoma group (0.98 ± 0.13) × 10- 3mm2/s(t 5.179,P <0.001);RADC value in non lumpy mastitis group was 0.73 ± 0.18, and rADC value in non lumpy invasive ductal carcinoma group was 0.55 ± 0.11 (t 3.764, P < 0.001). The best diagnostic cut-off point of ADC value is 1.15 × 10-3mm2/s, the area under the ROC curve is 0.911, the sensitivity is 78.9%, the specificity is 95%, the best diagnostic dividing point of rADC value is 0.655, the area under the ROC curve is 0.791, the sensitivity is 68.4%, and the specificity is 90%. Conclusion: ADC value and rADC value can be used to distinguish non lumpy mastitis from non lumpy invasive ductal carcinoma, and the diagnostic accuracy of ADC value is higher.
