Bloodletting therapy, as an ancient medical technology, has been applied around the world for thousands of years. In Arab region, bloodletting therapy is called Al-Hijamah which is analogous to the bloodletting and cu...Bloodletting therapy, as an ancient medical technology, has been applied around the world for thousands of years. In Arab region, bloodletting therapy is called Al-Hijamah which is analogous to the bloodletting and cupping in traditional Chinese medicine. However, Al-Hijamah therapy has its own characteristics which are analyzed emphatically in this report, including strict operating procedure, prominent mental effect, emphasis on bloodletting time, extensive indications, definite contraindications and so forth.展开更多
2000年8月，Badgujar C D等在印度的马哈拉施特拉邦试验研究了不同种植密度和氮钾肥肥水灌溉水平对Grand Naine（大奈因）香蕉产量等的影响。种植密度处理为：（S1）传统密度。1．8米×1．8米，1穴1株。每公顷种植3086株；（S2）1．...2000年8月，Badgujar C D等在印度的马哈拉施特拉邦试验研究了不同种植密度和氮钾肥肥水灌溉水平对Grand Naine（大奈因）香蕉产量等的影响。种植密度处理为：（S1）传统密度。1．8米×1．8米，1穴1株。每公顷种植3086株；（S2）1．8米×1．8米，1穴2株，每公顷种植6172株。展开更多
In this paper we analyse the motion of an electric vehicle,when there is only the pure rolling of the wheels on the ground.The equations of holonomic and non-holonomic constraints have been rendered explicitly obtaini...In this paper we analyse the motion of an electric vehicle,when there is only the pure rolling of the wheels on the ground.The equations of holonomic and non-holonomic constraints have been rendered explicitly obtaining 27 equations algebraic-differential system with the same number of unknowns.Besides,this system supplies a model to calculate the bonding reaction forces.展开更多
It is observed in clinical practice that worse healing in rotator cuff tear(RCT)is closely associated with osteo-porosis in patients.Herein,from the statistical analysis,we further confirmed that the RCT is significan...It is observed in clinical practice that worse healing in rotator cuff tear(RCT)is closely associated with osteo-porosis in patients.Herein,from the statistical analysis,we further confirmed that the RCT is significantly increased in postmenopausal women who suffer from decreased bone mineral density(BMD),suggesting intervention of osteoporosis as a potential strategy in the management of RCT in aged women.Our previous studies showed that Growth arrest-specific 5(GAS5),a long non-coding RNA(lncRNA),could promote bone formation,and alleviate osteoporosis.Herein,we demonstrated an enhancement of RCT healing by intraarticular administration of the GAS5 delivered with lipid nanoparticles(LNPs).Firstly,different kinds of ionizable lipids were applied to screen the capability of LNPs to deliver GAS5 in vitro to bone marrow mesenchymal stem cells(BMSCs)and the best-performing lipid was applied for in vivo evaluation in treating RCT rat models with osteoporosis by intraarticular injection.We found that GAS5-LNPs could improve bone quality and macrophage transformation into M2 type of the models with osteoporosis and facilitate healing of RCT.The therapeutic outcome with RCT rats demonstrated that tendon morphology,mechanical properties and bone quality of the rotator cuff were greatly improved.Thus,this study provides a new strategy to treat RCT by improving bone quality with formulated GAS5 by LNP,which is promising for clinical application.展开更多
文摘Bloodletting therapy, as an ancient medical technology, has been applied around the world for thousands of years. In Arab region, bloodletting therapy is called Al-Hijamah which is analogous to the bloodletting and cupping in traditional Chinese medicine. However, Al-Hijamah therapy has its own characteristics which are analyzed emphatically in this report, including strict operating procedure, prominent mental effect, emphasis on bloodletting time, extensive indications, definite contraindications and so forth.
文摘2000年8月，Badgujar C D等在印度的马哈拉施特拉邦试验研究了不同种植密度和氮钾肥肥水灌溉水平对Grand Naine（大奈因）香蕉产量等的影响。种植密度处理为：（S1）传统密度。1．8米×1．8米，1穴1株。每公顷种植3086株；（S2）1．8米×1．8米，1穴2株，每公顷种植6172株。
文摘In this paper we analyse the motion of an electric vehicle,when there is only the pure rolling of the wheels on the ground.The equations of holonomic and non-holonomic constraints have been rendered explicitly obtaining 27 equations algebraic-differential system with the same number of unknowns.Besides,this system supplies a model to calculate the bonding reaction forces.
基金supported by the National Natural Science Foundation of China(NO.81972067)the Fundamental Research Funds for the Central Universities,Sun Yat-sen University(NO.2020004)Natural Science Foundation of Guangdong Province(2022A1515012305).
文摘It is observed in clinical practice that worse healing in rotator cuff tear(RCT)is closely associated with osteo-porosis in patients.Herein,from the statistical analysis,we further confirmed that the RCT is significantly increased in postmenopausal women who suffer from decreased bone mineral density(BMD),suggesting intervention of osteoporosis as a potential strategy in the management of RCT in aged women.Our previous studies showed that Growth arrest-specific 5(GAS5),a long non-coding RNA(lncRNA),could promote bone formation,and alleviate osteoporosis.Herein,we demonstrated an enhancement of RCT healing by intraarticular administration of the GAS5 delivered with lipid nanoparticles(LNPs).Firstly,different kinds of ionizable lipids were applied to screen the capability of LNPs to deliver GAS5 in vitro to bone marrow mesenchymal stem cells(BMSCs)and the best-performing lipid was applied for in vivo evaluation in treating RCT rat models with osteoporosis by intraarticular injection.We found that GAS5-LNPs could improve bone quality and macrophage transformation into M2 type of the models with osteoporosis and facilitate healing of RCT.The therapeutic outcome with RCT rats demonstrated that tendon morphology,mechanical properties and bone quality of the rotator cuff were greatly improved.Thus,this study provides a new strategy to treat RCT by improving bone quality with formulated GAS5 by LNP,which is promising for clinical application.
