The microbiome,particularly the compo-sition and diversity of microbial communi-ties within various tissues,influences cancer development,progression and therapy response across various malignancies.1-5 Understanding ...The microbiome,particularly the compo-sition and diversity of microbial communi-ties within various tissues,influences cancer development,progression and therapy response across various malignancies.1-5 Understanding specific microbial signatures associated with cancers,termed the onco-biome,is crucial for advancing diagnostic and therapeutic strategies.展开更多
基金supported by R01 HL148801-02S1.AmZ is supported by the Prevent Cancer Foundation Grant,and NIH grants R21 CA259921,R01 AI163483,R01 EB030134 and U01 CA265719supported in part by the Department of Veterans Affairs,Veterans Health Administration,Office of Research and Development(VA Merit BLR&D Award I01 BX005707 to AmZ)+4 种基金RL receives funding support from NIH grants U01 DK061734,U01 DK130190,R01 DK106419,R01 DK121378,R01 DK124318 and P01 HL147835,as well as the John C Martin Foundation(RP124)KC is supported by AGA Research Foundation(AGA Research Scholar Award AGA2022-13-05)KC and CG are supported by NIH P30 CA023100 and R01 CA270235.AlZ has received funding support related to this study from NIH UH2 TR002087UH3 TR002087.RK is supported by NIH U24 CA248454,Pioneer DP1 AT010885 and R01 CA241728All authors receive institutional support from NIH P30 DK120515,P30 DK063491,P30 CA014195,P50 AA011999 and UL1 TR001442.
文摘The microbiome,particularly the compo-sition and diversity of microbial communi-ties within various tissues,influences cancer development,progression and therapy response across various malignancies.1-5 Understanding specific microbial signatures associated with cancers,termed the onco-biome,is crucial for advancing diagnostic and therapeutic strategies.