An efficient synthesis of 6-arylindazolo[2,3-a]quinolines starting from 2-aryl-2H-indazoles with sulfoxonium ylides via rhodium(Ⅲ)-catalyzed C-H activation and cyclization reaction has been described.This transformat...An efficient synthesis of 6-arylindazolo[2,3-a]quinolines starting from 2-aryl-2H-indazoles with sulfoxonium ylides via rhodium(Ⅲ)-catalyzed C-H activation and cyclization reaction has been described.This transformation features high efficiency,tolerates various functional groups,avoids external oxidant and produces dimethyl sulfoxide(DMSO)and H2O as the sole by-products.In addition,the scale-up reaction demonstrated the practicability of this protocol in industry.展开更多
文摘An efficient synthesis of 6-arylindazolo[2,3-a]quinolines starting from 2-aryl-2H-indazoles with sulfoxonium ylides via rhodium(Ⅲ)-catalyzed C-H activation and cyclization reaction has been described.This transformation features high efficiency,tolerates various functional groups,avoids external oxidant and produces dimethyl sulfoxide(DMSO)and H2O as the sole by-products.In addition,the scale-up reaction demonstrated the practicability of this protocol in industry.
