The study area Caofeidian 18-1/2 structure is located in the Shadongnan structural belt at the southeast subduction end of the Shaleitian salient in the western Bohai Sea. The characteristics of reservoirs and fluid i...The study area Caofeidian 18-1/2 structure is located in the Shadongnan structural belt at the southeast subduction end of the Shaleitian salient in the western Bohai Sea. The characteristics of reservoirs and fluid inclusions from 13 core samples near the buried hills in the study area are studied,and regional geology and conditions for reservoir formation are analyzed to reveal the characteristics and the processes of reservoir formation. Phase I oil and gas inclusions are mainly developed,and the abundance of oil and gas inclusions in this period is high( GOI is about 15%). The homogenization temperature of the hydrocarbon-containing brine inclusions accompanying them is mainly 90-120 ℃ . The simulation results of burial history and thermal history show that the main charging period of oil and gas is the present Himalayan tectonic movement period since 8 Ma,and mainly through unconformities,faults,and drainage systems,they are migrated and accumulated into fault anticline traps of Dongying Formation mudstone( E_d).展开更多
Objective To observe the influence of Kaixin Powder on ethology,content of 5-HT in the hippocampus, expression of m RNA, and protein in 5-HT1 A and 5-HT2 A receptors in the hippocampus of depressed rats induced by chr...Objective To observe the influence of Kaixin Powder on ethology,content of 5-HT in the hippocampus, expression of m RNA, and protein in 5-HT1 A and 5-HT2 A receptors in the hippocampus of depressed rats induced by chronic unpredictable mild stress（CUMS）. Methods Twenty-four male Wistar rats were randomly divided into blank,model, Trazodone, and Kaixin Powder groups, six rats in each group. In addition to the blank control group, other groups were established the depression model induced by CUMS combined with isolated feeding. At the same time, Trazodone group and Kaixin Powder group were treated with corresponding drugs for 3 weeks. After 3 weeks of administration, the rats were sacrificed, and a series of indexes were measured such as the contents of 5-HT, m RNA expression levels of 5-HT1 A and 5-HT2 A receptors, protein expression levels of 5-HT1 A and 5-HT2 A receptors, and so on. Results A series of indexes in the model group were decreased significantly such as the body weight growth, the sugar water intake, the score of Open Field Test, the content of5-HT in the hippocampus, expression of m RNA, and protein in 5-HT1 A receptor, while the expression of m RNA and protein in 5-HT2 A receptor were increased significantly.Compared with the model group, the indexes were ameliorated in Trazodone and Kaixin Powder groups. Kaixin Powder is better than Trazodone in decreasing the level of protein in 5-HT2 A receptor. Conclusion The result indicated that the depression performance of depressed rats induced by CUMS can be ameliorated by Kaixin Powder,and the mechanism maybe concerned with increasing the contents of 5-HT, exciting 5-HT1 A receptor, and antagonising 5- HT2 A receptor.展开更多
基金Supported by Tianjin Branch of CNOOC(China)Co.,Ltd.(CCL2014TJX ZSS0870)。
文摘The study area Caofeidian 18-1/2 structure is located in the Shadongnan structural belt at the southeast subduction end of the Shaleitian salient in the western Bohai Sea. The characteristics of reservoirs and fluid inclusions from 13 core samples near the buried hills in the study area are studied,and regional geology and conditions for reservoir formation are analyzed to reveal the characteristics and the processes of reservoir formation. Phase I oil and gas inclusions are mainly developed,and the abundance of oil and gas inclusions in this period is high( GOI is about 15%). The homogenization temperature of the hydrocarbon-containing brine inclusions accompanying them is mainly 90-120 ℃ . The simulation results of burial history and thermal history show that the main charging period of oil and gas is the present Himalayan tectonic movement period since 8 Ma,and mainly through unconformities,faults,and drainage systems,they are migrated and accumulated into fault anticline traps of Dongying Formation mudstone( E_d).
基金National Natural Science Fund of China(NO.81072744)
文摘Objective To observe the influence of Kaixin Powder on ethology,content of 5-HT in the hippocampus, expression of m RNA, and protein in 5-HT1 A and 5-HT2 A receptors in the hippocampus of depressed rats induced by chronic unpredictable mild stress（CUMS）. Methods Twenty-four male Wistar rats were randomly divided into blank,model, Trazodone, and Kaixin Powder groups, six rats in each group. In addition to the blank control group, other groups were established the depression model induced by CUMS combined with isolated feeding. At the same time, Trazodone group and Kaixin Powder group were treated with corresponding drugs for 3 weeks. After 3 weeks of administration, the rats were sacrificed, and a series of indexes were measured such as the contents of 5-HT, m RNA expression levels of 5-HT1 A and 5-HT2 A receptors, protein expression levels of 5-HT1 A and 5-HT2 A receptors, and so on. Results A series of indexes in the model group were decreased significantly such as the body weight growth, the sugar water intake, the score of Open Field Test, the content of5-HT in the hippocampus, expression of m RNA, and protein in 5-HT1 A receptor, while the expression of m RNA and protein in 5-HT2 A receptor were increased significantly.Compared with the model group, the indexes were ameliorated in Trazodone and Kaixin Powder groups. Kaixin Powder is better than Trazodone in decreasing the level of protein in 5-HT2 A receptor. Conclusion The result indicated that the depression performance of depressed rats induced by CUMS can be ameliorated by Kaixin Powder,and the mechanism maybe concerned with increasing the contents of 5-HT, exciting 5-HT1 A receptor, and antagonising 5- HT2 A receptor.
