The term“Cardiovascular-Kidney-Metabolic(CKM)syndrome”has emerged over the past few years to underscore the close and interactive relationship between diabetes mellitus,dyslipidemia,excess adiposity,hypertension,car...The term“Cardiovascular-Kidney-Metabolic(CKM)syndrome”has emerged over the past few years to underscore the close and interactive relationship between diabetes mellitus,dyslipidemia,excess adiposity,hypertension,cardiovascular complications,and chronic kidney disease(CKD).[1]It is defined and classified into five stages,ranging from the absence of CKM risk factors(Stage 0)to the establishment of clinical cardiovascular disease(CVD)(Stage 4),which highlights the progressive nature of its pathophysiology and the need for early identification for timely management to prevent the progression of CKM syndrome.[1]These CKM conditions often coexist in the same patient,and each exerts a negative impact on the progression of the other conditions,resulting in worsening of a patient’s clinical outcome.The prevalence of patients with CKM abnormalities is rapidly increasing globally,especially in Southeast Asia region,and projected to continue to increase through 2046.[2]In addition to the morbidity,mortality,and suffering imparted on patients and their families,CKM diseases present an escalating healthcare burden to society.展开更多
文摘The term“Cardiovascular-Kidney-Metabolic(CKM)syndrome”has emerged over the past few years to underscore the close and interactive relationship between diabetes mellitus,dyslipidemia,excess adiposity,hypertension,cardiovascular complications,and chronic kidney disease(CKD).[1]It is defined and classified into five stages,ranging from the absence of CKM risk factors(Stage 0)to the establishment of clinical cardiovascular disease(CVD)(Stage 4),which highlights the progressive nature of its pathophysiology and the need for early identification for timely management to prevent the progression of CKM syndrome.[1]These CKM conditions often coexist in the same patient,and each exerts a negative impact on the progression of the other conditions,resulting in worsening of a patient’s clinical outcome.The prevalence of patients with CKM abnormalities is rapidly increasing globally,especially in Southeast Asia region,and projected to continue to increase through 2046.[2]In addition to the morbidity,mortality,and suffering imparted on patients and their families,CKM diseases present an escalating healthcare burden to society.
